DE69127222D1 - Verfahren zur Herstellung von Epoxyalkoholen von hoher optischer Reinheit - Google Patents

Verfahren zur Herstellung von Epoxyalkoholen von hoher optischer Reinheit

Info

Publication number
DE69127222D1
DE69127222D1 DE69127222T DE69127222T DE69127222D1 DE 69127222 D1 DE69127222 D1 DE 69127222D1 DE 69127222 T DE69127222 T DE 69127222T DE 69127222 T DE69127222 T DE 69127222T DE 69127222 D1 DE69127222 D1 DE 69127222D1
Authority
DE
Germany
Prior art keywords
preparation
optical purity
high optical
epoxy alcohols
alcohols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69127222T
Other languages
English (en)
Other versions
DE69127222T2 (de
Inventor
Wilfred Po-Sum Shum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lyondell Chemical Technology LP
Original Assignee
Arco Chemical Technology LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arco Chemical Technology LP filed Critical Arco Chemical Technology LP
Application granted granted Critical
Publication of DE69127222D1 publication Critical patent/DE69127222D1/de
Publication of DE69127222T2 publication Critical patent/DE69127222T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69127222T 1990-04-26 1991-04-25 Verfahren zur Herstellung von Epoxyalkoholen von hoher optischer Reinheit Expired - Fee Related DE69127222T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51600190A 1990-04-26 1990-04-26

Publications (2)

Publication Number Publication Date
DE69127222D1 true DE69127222D1 (de) 1997-09-18
DE69127222T2 DE69127222T2 (de) 1997-12-04

Family

ID=24053692

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69127222T Expired - Fee Related DE69127222T2 (de) 1990-04-26 1991-04-25 Verfahren zur Herstellung von Epoxyalkoholen von hoher optischer Reinheit

Country Status (5)

Country Link
US (1) US5278070A (de)
EP (1) EP0454463B1 (de)
JP (1) JP3131742B2 (de)
CA (1) CA2039857A1 (de)
DE (1) DE69127222T2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI90995C (fi) * 1991-05-16 1994-04-25 Valtion Teknillinen Menetelmä kiraalisten yhdisteiden valmistamiseksi puhtaina optisina isomeereina
US6020174A (en) * 1992-07-27 2000-02-01 The Board Of Governors For Higher Education Chemoenzymatic synthesis of the taxol C-13 side chain N-benzolyl- (2R,3S)-Phenylisoserine
DE4225155C1 (de) * 1992-07-30 1993-08-05 Hoechst Ag, 6230 Frankfurt, De
DE69432576T2 (de) * 1993-02-15 2004-03-18 Daicel Chemical Industries, Ltd., Sakai Verfahren zur Herstellung von optischaktiven Epoxiden
US5354872A (en) * 1993-05-28 1994-10-11 Alcon Laboratories, Inc. Process for preparation of calcitriol lactone and related intermediates
AT401385B (de) * 1994-03-30 1996-08-26 Chemie Linz Gmbh Enzymatische racematspaltung asymmetrischer alkohole mittels vinylestern mehrbasiger carbonsäuren
DE4414273A1 (de) * 1994-04-23 1995-10-26 Chemie Linz Deutschland Enzymatische Racematspaltung asymmetrischer Alkohole mittels Vinylestern mehrbasiger Carbonsäuren
US6133485A (en) * 1998-04-15 2000-10-17 Synphar Laboratories, Inc. Asymmetric synthesis of 2-(2,4-difluorophenyl)-1-heterocycl-1-yl butan-2,3-diols
ES2159231B1 (es) * 1999-04-09 2002-05-16 Smithkline Beecham Sa Procedimiento de resolucion de mezclas enantiomericas de alcoholes catalizada por lipasas.
KR100379756B1 (ko) * 2000-10-02 2003-04-11 한국과학기술연구원 이성질체 분할방법
KR100981555B1 (ko) * 2008-03-18 2010-09-10 경희대학교 산학협력단 (2ｒ,3ｓ)-(3-(치환된메틸)-옥시란-2-일)메탄올의 신규한제조방법
US20150315114A1 (en) * 2012-12-07 2015-11-05 Cayman Chemical Company Incorporated Methods of Synthesizing a Prostacyclin Analog

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594439A (en) * 1980-08-06 1986-06-10 The Board Of Trustees Of The Leland Stanford Jr. University Method for asymmetric epoxidation
US4471130A (en) * 1980-08-06 1984-09-11 The Board Of Trustees Of The Leland Stanford Junior University Method for asymmetric epoxidation
EP0070618A1 (de) * 1981-06-19 1983-01-26 Imperial Chemical Industries Plc Asymmetrisches Epoxidationsverfahren
US4732853A (en) * 1984-11-21 1988-03-22 President And Fellows Of Harvard College Method of making chiral epoxy alcohols
IL78187A (en) * 1985-04-04 1991-05-12 Massachusetts Inst Technology Catalytic asymmetric epoxidation
US4902812A (en) * 1986-07-31 1990-02-20 Nissan Chemical Industries, Ltd. Optically active alcohols, process for producing the same, and process for resolving the same
US4916074A (en) * 1986-10-30 1990-04-10 Chisso Corporation Process for producing optically active compounds
US4764628A (en) * 1987-09-14 1988-08-16 Arco Chemical Company Asymmetric epoxidation of allylic alcohols
CH674649A5 (de) * 1988-03-17 1990-06-29 Lonza Ag
IT1217765B (it) * 1988-06-02 1990-03-30 Montedison Spa Processo per la risoluzione enzimatica degli isomeri ottici di derivati racemi esterei dell,acido 3 mercapto 2 alchilpropionico
DE3819467A1 (de) * 1988-06-08 1989-12-14 Basf Ag Verfahren zur herstellung eines biokatalysators und dessen verwendung zur razematspaltung
US4923810A (en) * 1988-08-24 1990-05-08 Genzyme Corporation Resolution of glycidyl esters to high enantiomeric excess
US5106750A (en) * 1988-08-30 1992-04-21 G. D. Searle & Co. Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
JP3027442B2 (ja) * 1990-10-30 2000-04-04 日東電工株式会社 光学活性エポキシアルコールの製法

Also Published As

Publication number Publication date
DE69127222T2 (de) 1997-12-04
EP0454463A3 (en) 1992-09-23
EP0454463B1 (de) 1997-08-13
JPH04228094A (ja) 1992-08-18
CA2039857A1 (en) 1991-10-27
EP0454463A2 (de) 1991-10-30
JP3131742B2 (ja) 2001-02-05
US5278070A (en) 1994-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee