DE69124683D1 - Monoklonale Antikörper gegen Glykolipid-Karbohydratketten - Google Patents

Monoklonale Antikörper gegen Glykolipid-Karbohydratketten

Info

Publication number
DE69124683D1
DE69124683D1 DE69124683T DE69124683T DE69124683D1 DE 69124683 D1 DE69124683 D1 DE 69124683D1 DE 69124683 T DE69124683 T DE 69124683T DE 69124683 T DE69124683 T DE 69124683T DE 69124683 D1 DE69124683 D1 DE 69124683D1
Authority
DE
Germany
Prior art keywords
monoclonal antibodies
antibodies against
carbohydrate chains
glycolipid carbohydrate
against glycolipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69124683T
Other languages
English (en)
Other versions
DE69124683T2 (de
Inventor
Nobuo Hanai
So Ohta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of DE69124683D1 publication Critical patent/DE69124683D1/de
Application granted granted Critical
Publication of DE69124683T2 publication Critical patent/DE69124683T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69124683T 1990-11-30 1991-11-29 Monoklonale Antikörper gegen Glykolipid-Karbohydratketten Expired - Lifetime DE69124683T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33465990 1990-11-30

Publications (2)

Publication Number Publication Date
DE69124683D1 true DE69124683D1 (de) 1997-03-27
DE69124683T2 DE69124683T2 (de) 1997-09-11

Family

ID=18279829

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69124683T Expired - Lifetime DE69124683T2 (de) 1990-11-30 1991-11-29 Monoklonale Antikörper gegen Glykolipid-Karbohydratketten

Country Status (6)

Country Link
EP (1) EP0493686B1 (de)
AT (1) ATE148922T1 (de)
DE (1) DE69124683T2 (de)
DK (1) DK0493686T3 (de)
ES (1) ES2098304T3 (de)
GR (1) GR3023290T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2078539C (en) 1991-09-18 2005-08-02 Kenya Shitara Process for producing humanized chimera antibody
DE4208795A1 (de) * 1992-03-19 1993-09-23 Behringwerke Ag Monoklonaler anti-gangliosid-antikoerper, seine herstellung und verwendung als tumortherapeutikum
AU4801093A (en) * 1992-07-31 1994-03-03 Duke University Monoclonal antibodies specific for 3',6'-isold1 ganglioside
AU784187B2 (en) 1999-09-30 2006-02-16 Kyowa Hakko Kogyo Co. Ltd. Human type complementarity determining region transplantation antibody against ganglioside GD3 and derivatives of antibody against ganglioside GD3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0234122A3 (de) * 1986-02-21 1989-03-22 Oncogen Limited Partnership Tumortherapie mit biologisch aktiven Anti-Tumor-Antikörpern
US4849509A (en) * 1987-02-20 1989-07-18 The Wistar Institute Monoclonal antibodies against melanoma-associated antigens and hybrid cell lines producing these antibodies

Also Published As

Publication number Publication date
EP0493686A1 (de) 1992-07-08
EP0493686B1 (de) 1997-02-12
ES2098304T3 (es) 1997-05-01
ATE148922T1 (de) 1997-02-15
DK0493686T3 (da) 1997-03-10
DE69124683T2 (de) 1997-09-11
JPH05176791A (ja) 1993-07-20
GR3023290T3 (en) 1997-07-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: KYOWA HAKKO KIRIN CO., LTD., TOKYO, JP