GB2259093A - Modified antibodies - Google Patents
Modified antibodiesInfo
- Publication number
- GB2259093A GB2259093A GB9223676A GB9223676A GB2259093A GB 2259093 A GB2259093 A GB 2259093A GB 9223676 A GB9223676 A GB 9223676A GB 9223676 A GB9223676 A GB 9223676A GB 2259093 A GB2259093 A GB 2259093A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antibodies
- modified
- precipitate
- modified antibodies
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention relates to modified forms of antibodies having specificities against polysaccharide antigenic determinants which antibodies in the native form produce a precipitate on storage at 4 DEG C in aqueous solution said modified antibodies carrying modified glycosyl groups and on storage in aqueous solution at 4 DEG C producing substantially no precipitate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909010944A GB9010944D0 (en) | 1990-05-16 | 1990-05-16 | Chemical compounds |
PCT/EP1991/000921 WO1991018106A1 (en) | 1990-05-16 | 1991-05-15 | Modified antibodies |
Publications (3)
Publication Number | Publication Date |
---|---|
GB9223676D0 GB9223676D0 (en) | 1993-01-06 |
GB2259093A true GB2259093A (en) | 1993-03-03 |
GB2259093B GB2259093B (en) | 1994-04-06 |
Family
ID=10676067
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB909010944A Pending GB9010944D0 (en) | 1990-05-16 | 1990-05-16 | Chemical compounds |
GB9223676A Expired - Fee Related GB2259093B (en) | 1990-05-16 | 1992-11-12 | Antibodies comprising modified glycosyl groups |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB909010944A Pending GB9010944D0 (en) | 1990-05-16 | 1990-05-16 | Chemical compounds |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU7862291A (en) |
GB (2) | GB9010944D0 (en) |
WO (1) | WO1991018106A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5452835B2 (en) | 2003-07-15 | 2014-03-26 | 中外製薬株式会社 | Production of IgM by transformed cells and its quantification method |
ATE518888T1 (en) | 2003-10-09 | 2011-08-15 | Chugai Pharmaceutical Co Ltd | STABILIZED SOLUTION WITH HIGH IGM CONCENTRATION |
JP4671864B2 (en) | 2003-10-09 | 2011-04-20 | 中外製薬株式会社 | Method for stabilizing protein solutions |
-
1990
- 1990-05-16 GB GB909010944A patent/GB9010944D0/en active Pending
-
1991
- 1991-05-15 AU AU78622/91A patent/AU7862291A/en not_active Abandoned
- 1991-05-15 WO PCT/EP1991/000921 patent/WO1991018106A1/en unknown
-
1992
- 1992-11-12 GB GB9223676A patent/GB2259093B/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB2259093B (en) | 1994-04-06 |
GB9010944D0 (en) | 1990-07-04 |
WO1991018106A1 (en) | 1991-11-28 |
AU7862291A (en) | 1991-12-10 |
GB9223676D0 (en) | 1993-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20100515 |