GB2259093A - Modified antibodies - Google Patents

Modified antibodies

Info

Publication number
GB2259093A
GB2259093A GB9223676A GB9223676A GB2259093A GB 2259093 A GB2259093 A GB 2259093A GB 9223676 A GB9223676 A GB 9223676A GB 9223676 A GB9223676 A GB 9223676A GB 2259093 A GB2259093 A GB 2259093A
Authority
GB
United Kingdom
Prior art keywords
antibodies
modified
precipitate
modified antibodies
aqueous solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9223676A
Other versions
GB2259093B (en
GB9223676D0 (en
Inventor
Philip Allan Judson
Jonathan Spencer Smythe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Central Blood Laboratories Authority
Original Assignee
Central Blood Laboratories Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Central Blood Laboratories Authority filed Critical Central Blood Laboratories Authority
Publication of GB9223676D0 publication Critical patent/GB9223676D0/en
Publication of GB2259093A publication Critical patent/GB2259093A/en
Application granted granted Critical
Publication of GB2259093B publication Critical patent/GB2259093B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to modified forms of antibodies having specificities against polysaccharide antigenic determinants which antibodies in the native form produce a precipitate on storage at 4 DEG C in aqueous solution said modified antibodies carrying modified glycosyl groups and on storage in aqueous solution at 4 DEG C producing substantially no precipitate.
GB9223676A 1990-05-16 1992-11-12 Antibodies comprising modified glycosyl groups Expired - Fee Related GB2259093B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909010944A GB9010944D0 (en) 1990-05-16 1990-05-16 Chemical compounds
PCT/EP1991/000921 WO1991018106A1 (en) 1990-05-16 1991-05-15 Modified antibodies

Publications (3)

Publication Number Publication Date
GB9223676D0 GB9223676D0 (en) 1993-01-06
GB2259093A true GB2259093A (en) 1993-03-03
GB2259093B GB2259093B (en) 1994-04-06

Family

ID=10676067

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909010944A Pending GB9010944D0 (en) 1990-05-16 1990-05-16 Chemical compounds
GB9223676A Expired - Fee Related GB2259093B (en) 1990-05-16 1992-11-12 Antibodies comprising modified glycosyl groups

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909010944A Pending GB9010944D0 (en) 1990-05-16 1990-05-16 Chemical compounds

Country Status (3)

Country Link
AU (1) AU7862291A (en)
GB (2) GB9010944D0 (en)
WO (1) WO1991018106A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5452835B2 (en) 2003-07-15 2014-03-26 中外製薬株式会社 Production of IgM by transformed cells and its quantification method
JP4671864B2 (en) 2003-10-09 2011-04-20 中外製薬株式会社 Method for stabilizing protein solutions
ATE518888T1 (en) 2003-10-09 2011-08-15 Chugai Pharmaceutical Co Ltd STABILIZED SOLUTION WITH HIGH IGM CONCENTRATION

Also Published As

Publication number Publication date
AU7862291A (en) 1991-12-10
GB9010944D0 (en) 1990-07-04
GB2259093B (en) 1994-04-06
WO1991018106A1 (en) 1991-11-28
GB9223676D0 (en) 1993-01-06

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20100515