DE69123012D1 - Rekombinantes Milben-Allergen - Google Patents

Rekombinantes Milben-Allergen

Info

Publication number
DE69123012D1
DE69123012D1 DE69123012T DE69123012T DE69123012D1 DE 69123012 D1 DE69123012 D1 DE 69123012D1 DE 69123012 T DE69123012 T DE 69123012T DE 69123012 T DE69123012 T DE 69123012T DE 69123012 D1 DE69123012 D1 DE 69123012D1
Authority
DE
Germany
Prior art keywords
mite allergen
recombinant mite
recombinant
allergen
mite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69123012T
Other languages
English (en)
Other versions
DE69123012T2 (de
Inventor
Satoru Oka
Kazuhisa Ono
Seiko Shigeta
Takeshi Wada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fumakilla Ltd
Hiroshima University NUC
Original Assignee
Fumakilla Ltd
Hiroshima University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fumakilla Ltd, Hiroshima University NUC filed Critical Fumakilla Ltd
Publication of DE69123012D1 publication Critical patent/DE69123012D1/de
Application granted granted Critical
Publication of DE69123012T2 publication Critical patent/DE69123012T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds
    • Y10S530/858—Proteins from animals other than mammals or birds insects; venom

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69123012T 1990-08-27 1991-08-27 Rekombinantes Milben-Allergen Expired - Lifetime DE69123012T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22588690 1990-08-27
JP32738290 1990-11-27
JP03104949A JP3139777B2 (ja) 1990-08-27 1991-03-09 組換えダニアレルゲン

Publications (2)

Publication Number Publication Date
DE69123012D1 true DE69123012D1 (de) 1996-12-12
DE69123012T2 DE69123012T2 (de) 1997-03-13

Family

ID=27310353

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69123012T Expired - Lifetime DE69123012T2 (de) 1990-08-27 1991-08-27 Rekombinantes Milben-Allergen

Country Status (7)

Country Link
US (2) US5314991A (de)
EP (1) EP0473111B1 (de)
JP (1) JP3139777B2 (de)
KR (1) KR0148020B1 (de)
AU (1) AU649704B2 (de)
CA (1) CA2050058C (de)
DE (1) DE69123012T2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5433948A (en) * 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
JP2596466B2 (ja) * 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するｄｎａおよび該アレルゲンの製造方法
JP3592709B2 (ja) * 1990-09-11 2004-11-24 インスティテュート・フォー・チャイルド・ヘルス・リサーチ ダーマトファゴイデス（家塵ダニ）のアレルゲンのクローニングおよびシークエンシング
JP3068879B2 (ja) * 1991-03-09 2000-07-24 フマキラー株式会社 精製ダニアレルゲン
US7288256B1 (en) * 1991-10-16 2007-10-30 Merck Patent Gmbh T cell epitopes of the major allergens from dermatophagoides (house dust mite)
US6849427B1 (en) * 1993-03-12 2005-02-01 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p VII, and uses therefor
WO1995002412A1 (fr) * 1993-07-16 1995-01-26 Meiji Milk Products Co., Ltd. Agent antiallergie
US6180771B1 (en) 1993-12-08 2001-01-30 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor
WO1995017424A1 (fr) * 1993-12-22 1995-06-29 Asahi Breweries, Ltd. NOUVELLE SUBSTANCE ALLERGENE DerI DE RECOMBINAISON, PRECURSEUR DE LADITE SUBSTANCE ET PROCEDE DE PRODUCTION
US20030202980A1 (en) * 1995-12-29 2003-10-30 Caplan Michael J. Methods and reagents for decreasing clinical reaction to allergy
GB9609252D0 (en) * 1996-05-02 1996-07-03 Mini Agriculture & Fisheries Vaccines
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
WO1999038978A1 (en) * 1998-01-31 1999-08-05 University Of Arkansas Methods and reagents for decreasing allergic reactions
US7879977B2 (en) 1998-01-31 2011-02-01 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
US6225444B1 (en) 1998-02-10 2001-05-01 Protarga, Inc. Neuroprotective peptides and uses thereof
US7128921B1 (en) * 1998-04-17 2006-10-31 Heska Corporation Dermatophagoides proteins and fragments thereof
US6455686B1 (en) 1998-04-17 2002-09-24 Heska Corporation Dermatophagoides nucleic acid molecules, proteins and uses thereof
SE515819C2 (sv) * 1999-02-25 2001-10-15 Statens Veterinaermedicinska A Protein från kvalstret Sarcoptes scabiei
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
DK1272213T3 (da) * 2000-04-06 2006-07-10 Seer Pharmaceuticals Llc Mikrobielt afgivelsessystem
US8246945B2 (en) * 2000-04-06 2012-08-21 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
US20050063994A1 (en) * 2000-04-06 2005-03-24 Caplan Michael J. Methods and reagents for decreasing clinical reaction to allergy
WO2002076402A2 (en) 2001-03-23 2002-10-03 Protarga, Inc. Fatty amine drug conjugates
AU2002305099A1 (en) * 2001-03-23 2002-10-08 Protarga, Inc. Fatty alcohol drug conjugates
KR20020075996A (ko) * 2001-03-27 2002-10-09 (주) 바이오알레텍 잎응애(귤응애, 점박이응애, 사과응애) 조항원을 함유하는피부시험 시약 및 혈청 특이 ＩｇＥ, ＩｇＧ 아형 항체검출 키트
DE10121463A1 (de) * 2001-05-02 2003-02-27 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
JP3977162B2 (ja) * 2002-06-21 2007-09-19 株式会社バンダイナムコゲームス キャラクタ情報管理装置、プログラム及び情報記憶媒体
NZ539061A (en) * 2002-08-29 2008-03-28 Univ Singapore Targeting an allergen to the MHC class II processing and presentation pathway in a vaccination group induces a strong Th1 immune response
WO2004078965A1 (ja) * 2003-03-05 2004-09-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 大腸菌における異種蛋白質の製造方法
KR101222496B1 (ko) 2004-04-09 2013-01-15 니뽄젠야쿠코교 가부시키가이샤 신규한 진드기 알러젠
KR102107056B1 (ko) 2017-09-22 2020-05-29 연세대학교 산학협력단 진드기에 대한 알레르기성 질환 진단용 조성물, 진드기에 대한 알레르기성 진단 방법, 및 진드기에 대한 알레르기성 질환을 예방 또는 치료하기 위한 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU624077B2 (en) * 1987-06-17 1992-06-04 Institute For Child Health Research Cloning of mite allergens

Also Published As

Publication number Publication date
US5405758A (en) 1995-04-11
KR0148020B1 (ko) 1998-08-01
CA2050058A1 (en) 1992-02-28
CA2050058C (en) 2001-06-12
EP0473111A3 (en) 1992-09-02
AU8271091A (en) 1992-03-05
JP3139777B2 (ja) 2001-03-05
EP0473111A2 (de) 1992-03-04
AU649704B2 (en) 1994-06-02
DE69123012T2 (de) 1997-03-13
JPH04288100A (ja) 1992-10-13
EP0473111B1 (de) 1996-11-06
KR920004572A (ko) 1992-03-27
US5314991A (en) 1994-05-24

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