DE69116552D1 - Verwendung von il-4 zur verstärkung der immunantwort auf infektiöse antigen-herausforderungen - Google Patents

Verwendung von il-4 zur verstärkung der immunantwort auf infektiöse antigen-herausforderungen

Info

Publication number
DE69116552D1
DE69116552D1 DE69116552T DE69116552T DE69116552D1 DE 69116552 D1 DE69116552 D1 DE 69116552D1 DE 69116552 T DE69116552 T DE 69116552T DE 69116552 T DE69116552 T DE 69116552T DE 69116552 D1 DE69116552 D1 DE 69116552D1
Authority
DE
Germany
Prior art keywords
immune response
agents
strengthen
inducing
mammals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69116552T
Other languages
English (en)
Other versions
DE69116552T2 (de
Inventor
Jerome A East Th Stre Schwartz
Claude Nash
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE69116552D1 publication Critical patent/DE69116552D1/de
Publication of DE69116552T2 publication Critical patent/DE69116552T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2026—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69116552T 1990-03-21 1991-03-19 Verwendung von il-4 zur verstärkung der immunantwort auf infektiöse antigen-herausforderungen Expired - Fee Related DE69116552T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49683290A 1990-03-21 1990-03-21
PCT/US1991/001733 WO1991014450A1 (en) 1990-03-21 1991-03-19 Use of il-4 to enhance immune response to infectious antigenic challenges

Publications (2)

Publication Number Publication Date
DE69116552D1 true DE69116552D1 (de) 1996-02-29
DE69116552T2 DE69116552T2 (de) 1996-05-30

Family

ID=23974340

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69116552T Expired - Fee Related DE69116552T2 (de) 1990-03-21 1991-03-19 Verwendung von il-4 zur verstärkung der immunantwort auf infektiöse antigen-herausforderungen

Country Status (19)

Country Link
EP (1) EP0521916B1 (de)
JP (1) JPH05505799A (de)
CN (1) CN1055116A (de)
AT (1) ATE133074T1 (de)
AU (1) AU656889B2 (de)
CA (1) CA2078676A1 (de)
DE (1) DE69116552T2 (de)
DK (1) DK0521916T3 (de)
ES (1) ES2082201T3 (de)
FI (1) FI924215A0 (de)
GR (1) GR3019018T3 (de)
HU (1) HUT63062A (de)
IE (1) IE72204B1 (de)
IL (1) IL97600A0 (de)
MY (1) MY108672A (de)
OA (1) OA09672A (de)
PT (1) PT97082B (de)
WO (1) WO1991014450A1 (de)
ZA (1) ZA912037B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100191223B1 (ko) * 1989-07-28 1999-06-15 둘락 노먼 씨. 인터루킨-4의 정제방법 및 이를 함유하는 약제학적 조성물
US5827670A (en) * 1990-08-02 1998-10-27 Fred Hutchinson Cancer Research Center Methods of isolating and detecting bone marrow stromal cells with VCAM-1-specific antibodies
US7449186B1 (en) 1990-08-02 2008-11-11 Fred Hutchinson Cancer Research Center Methods of blocking the interaction between stromal cells and hemopoietic cells with anti-VCAM-1 antibodies
CA2098726A1 (en) * 1990-12-19 1992-06-20 Edward J. Rozhon Use of il-4 to enhance immune response to immunogens in vaccines
JPH0747545B2 (ja) * 1991-01-10 1995-05-24 シェリング・コーポレーション 創傷治癒及び修復の修復段階を促進し、かつ感染した創傷及び糖尿病哺乳類の創傷の治癒を促進するためのｉｌ−４の用途
GB9124347D0 (en) * 1991-11-15 1992-01-08 Isis Innovation Treatment of macrophages
JP2711182B2 (ja) * 1992-08-19 1998-02-10 シェリング・コーポレーション Ｉｌ−４を用いるｈｉｖ複製を阻害する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80678A (en) * 1985-11-19 1999-05-09 Schering Biotech Corp Human interleukin-4
DE3882611T2 (de) * 1987-08-03 1993-12-23 Tasuku Honjo Menschliches Interleukin-4, Expressionsvektoren dafür und diese enthaltende Transformanten.
JPH0236129A (ja) * 1988-07-22 1990-02-06 Ajinomoto Co Inc ワクチン効果増強剤
EP0454736A4 (en) * 1989-01-20 1993-05-12 The University Of Melbourne Fibrinolysis

Also Published As

Publication number Publication date
OA09672A (en) 1993-05-15
CA2078676A1 (en) 1991-09-22
PT97082A (pt) 1991-11-29
HUT63062A (en) 1993-07-28
IE72204B1 (en) 1997-04-09
IL97600A0 (en) 1992-06-21
EP0521916B1 (de) 1996-01-17
EP0521916A1 (de) 1993-01-13
ATE133074T1 (de) 1996-02-15
ZA912037B (en) 1992-03-25
DE69116552T2 (de) 1996-05-30
PT97082B (pt) 1998-07-31
MY108672A (en) 1996-10-31
JPH05505799A (ja) 1993-08-26
IE910921A1 (en) 1991-09-25
GR3019018T3 (en) 1996-05-31
WO1991014450A1 (en) 1991-10-03
ES2082201T3 (es) 1996-03-16
FI924215A (fi) 1992-09-21
DK0521916T3 (da) 1996-03-04
CN1055116A (zh) 1991-10-09
AU656889B2 (en) 1995-02-23
AU7469091A (en) 1991-10-21
FI924215A0 (fi) 1992-09-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee