DE69112376D1 - Verbesserte Therapiemethode. - Google Patents

Verbesserte Therapiemethode.

Info

Publication number
DE69112376D1
DE69112376D1 DE69112376T DE69112376T DE69112376D1 DE 69112376 D1 DE69112376 D1 DE 69112376D1 DE 69112376 T DE69112376 T DE 69112376T DE 69112376 T DE69112376 T DE 69112376T DE 69112376 D1 DE69112376 D1 DE 69112376D1
Authority
DE
Germany
Prior art keywords
agent
therapy method
improved therapy
antifolate
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69112376T
Other languages
English (en)
Other versions
DE69112376T3 (de
DE69112376T2 (de
Inventor
Gerald Burr Grindey
Shih Chuan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24717023&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69112376(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69112376D1 publication Critical patent/DE69112376D1/de
Application granted granted Critical
Publication of DE69112376T2 publication Critical patent/DE69112376T2/de
Publication of DE69112376T3 publication Critical patent/DE69112376T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69112376T 1991-03-29 1991-09-17 Verbesserte Therapiemethode. Expired - Fee Related DE69112376T3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67703191A 1991-03-29 1991-03-29

Publications (3)

Publication Number Publication Date
DE69112376D1 true DE69112376D1 (de) 1995-09-28
DE69112376T2 DE69112376T2 (de) 1996-03-14
DE69112376T3 DE69112376T3 (de) 2002-08-14

Family

ID=24717023

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69112376T Expired - Fee Related DE69112376T3 (de) 1991-03-29 1991-09-17 Verbesserte Therapiemethode.

Country Status (12)

Country Link
EP (1) EP0505640B2 (de)
JP (1) JP3468534B2 (de)
AT (1) ATE126700T1 (de)
AU (1) AU640524B2 (de)
CA (1) CA2051520C (de)
CY (1) CY1888A (de)
DE (1) DE69112376T3 (de)
DK (1) DK0505640T4 (de)
ES (1) ES2077808T5 (de)
GR (1) GR3017774T3 (de)
HK (1) HK161495A (de)
ZA (1) ZA917406B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226842D0 (en) 1992-12-23 1993-02-17 Wellcome Found Pharmaceutical compounds
ES2284660T3 (es) * 2000-06-30 2007-11-16 Eli Lilly And Company Composicion que contiene un antiofolato y un agente que rebaja el acido metilmalonico.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931441A (en) † 1988-11-09 1990-06-05 Luitpold Pharmaceuticals, Inc. Stabilized aqueous leucovorin calcium compositions
US4999424A (en) * 1988-11-10 1991-03-12 The Pennsylvania State University GAR transformylase inhibitor
CH676981A5 (de) † 1988-11-11 1991-03-28 Eprova Ag
US5008391A (en) * 1989-07-07 1991-04-16 Eli Lilly And Company Enantioselective synthesis of antifolates

Also Published As

Publication number Publication date
DE69112376T3 (de) 2002-08-14
JP3468534B2 (ja) 2003-11-17
AU640524B2 (en) 1993-08-26
ATE126700T1 (de) 1995-09-15
DE69112376T2 (de) 1996-03-14
ES2077808T5 (es) 2002-10-16
CY1888A (en) 1996-04-05
HK161495A (en) 1995-10-20
EP0505640B2 (de) 2002-02-27
JPH0597705A (ja) 1993-04-20
EP0505640A1 (de) 1992-09-30
DK0505640T4 (da) 2002-12-16
CA2051520A1 (en) 1992-09-30
DK0505640T3 (da) 1995-12-27
AU8457091A (en) 1992-10-01
ES2077808T3 (es) 1995-12-01
ZA917406B (en) 1993-03-17
EP0505640B1 (de) 1995-08-23
CA2051520C (en) 2003-02-18
GR3017774T3 (en) 1996-01-31

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8339 Ceased/non-payment of the annual fee