DE69029884D1 - 5-Methylisoxazol-4-carbonsäure-anilide und 2-Hydroxyethyliden-cyanoessigsäure-anilide zur Behandlung von Augenkrankheiten - Google Patents

5-Methylisoxazol-4-carbonsäure-anilide und 2-Hydroxyethyliden-cyanoessigsäure-anilide zur Behandlung von Augenkrankheiten

Info

Publication number
DE69029884D1
DE69029884D1 DE69029884T DE69029884T DE69029884D1 DE 69029884 D1 DE69029884 D1 DE 69029884D1 DE 69029884 T DE69029884 T DE 69029884T DE 69029884 T DE69029884 T DE 69029884T DE 69029884 D1 DE69029884 D1 DE 69029884D1
Authority
DE
Germany
Prior art keywords
acid anilides
hydroxyethylidene
methylisoxazole
treatment
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029884T
Other languages
English (en)
Other versions
DE69029884T2 (de
Inventor
Stella M Robertson
Laura Smith Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of DE69029884D1 publication Critical patent/DE69029884D1/de
Application granted granted Critical
Publication of DE69029884T2 publication Critical patent/DE69029884T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
DE69029884T 1989-08-18 1990-08-16 5-Methylisoxazol-4-carbonsäure-anilide und 2-Hydroxyethyliden-cyanoessigsäure-anilide zur Behandlung von Augenkrankheiten Expired - Fee Related DE69029884T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39586089A 1989-08-18 1989-08-18

Publications (2)

Publication Number Publication Date
DE69029884D1 true DE69029884D1 (de) 1997-03-20
DE69029884T2 DE69029884T2 (de) 1997-08-14

Family

ID=23564835

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029884T Expired - Fee Related DE69029884T2 (de) 1989-08-18 1990-08-16 5-Methylisoxazol-4-carbonsäure-anilide und 2-Hydroxyethyliden-cyanoessigsäure-anilide zur Behandlung von Augenkrankheiten

Country Status (15)

Country Link
EP (1) EP0413329B1 (de)
JP (1) JP3131693B2 (de)
KR (1) KR100192745B1 (de)
AT (1) ATE148628T1 (de)
AU (1) AU633346B2 (de)
CA (1) CA2023560C (de)
DD (1) DD297328A5 (de)
DE (1) DE69029884T2 (de)
DK (1) DK0413329T3 (de)
ES (1) ES2099700T3 (de)
HU (1) HU215959B (de)
IE (1) IE902978A1 (de)
IL (1) IL95412A (de)
TW (1) TW287948B (de)
ZA (1) ZA906544B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0538783T3 (da) * 1991-10-23 1996-02-05 Hoechst Ag N-Phenyl-2-cyano-3-hydroxycrotonsyreamidderivater og deres anvendelse i lægemidler med immunmodulato riske egenskaber
TW314467B (de) * 1993-03-31 1997-09-01 Hoechst Ag
US5700823A (en) * 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
US5610173A (en) * 1994-01-07 1997-03-11 Sugen, Inc. Formulations for lipophilic compounds
US6335356B1 (en) 1994-01-07 2002-01-01 Sugen, Inc. Method of treating a patient by parenteral administration of a lipophilic compound
WO1996011682A1 (fr) * 1994-10-17 1996-04-25 Hoechst Pharmaceuticals & Chemicals K.K. Composition preventive et remede pour les maladies allergiques de type i
US5721277A (en) * 1995-04-21 1998-02-24 Sugen, Inc. Compounds and methods for inhibiting hyper-proliferative cell growth
US6331555B1 (en) 1995-06-01 2001-12-18 University Of California Treatment of platelet derived growth factor related disorders such as cancers
US6011051A (en) * 1996-07-31 2000-01-04 Hoechst Aktiengesellschaft Use of isoxazole and crotonamide derivatives for the modulation of apoptosis
US6316479B1 (en) 1997-05-19 2001-11-13 Sugen, Inc. Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders
DE102006017896A1 (de) † 2006-04-13 2007-10-25 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Leflunomid enthaltende pharmazeutische Zusammensetzungen
ES2960598T3 (es) 2014-05-08 2024-03-05 Kiora Pharmaceuticals Gmbh Compuestos para el tratamiento de enfermedades y trastornos oftálmicos
KR20230140410A (ko) * 2022-03-25 2023-10-06 바스테라 주식회사 3-페닐이속사졸 유도체 및 이를 유효성분으로 함유하는 안질환 예방 또는 치료용 약학 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
NL178596C (nl) * 1975-06-05 1986-04-16 Hoechst Ag Werkwijze voor het bereiden van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor het bereiden van daarin als geneeskrachtige verbindingen te gebruiken 5-methylisoxazool-4-carbonzuuraniliden.
DE2854439A1 (de) 1978-12-16 1980-07-03 Hoechst Ag Ein isoxazolderivat, verfahren zu seiner herstellung, diese verbindung enthaltende mittel und verwendung
DE3534440A1 (de) * 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
KR910004193A (ko) 1991-03-28
EP0413329A3 (en) 1992-04-15
JP3131693B2 (ja) 2001-02-05
CA2023560C (en) 2000-12-12
AU6110490A (en) 1991-02-21
CA2023560A1 (en) 1991-02-19
DK0413329T3 (da) 1997-08-18
EP0413329A2 (de) 1991-02-20
DE69029884T2 (de) 1997-08-14
TW287948B (de) 1996-10-11
DD297328A5 (de) 1992-01-09
IL95412A (en) 1996-01-31
AU633346B2 (en) 1993-01-28
IE902978A1 (en) 1991-02-27
ZA906544B (en) 1991-06-26
ES2099700T3 (es) 1997-06-01
HU215959B (hu) 1999-03-29
IL95412A0 (en) 1991-06-30
JPH0390024A (ja) 1991-04-16
ATE148628T1 (de) 1997-02-15
EP0413329B1 (de) 1997-02-05
HU905064D0 (en) 1991-01-28
HUT59600A (en) 1992-06-29
KR100192745B1 (ko) 1999-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee