DE69029738T2 - Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's - Google Patents

Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's

Info

Publication number
DE69029738T2
DE69029738T2 DE69029738T DE69029738T DE69029738T2 DE 69029738 T2 DE69029738 T2 DE 69029738T2 DE 69029738 T DE69029738 T DE 69029738T DE 69029738 T DE69029738 T DE 69029738T DE 69029738 T2 DE69029738 T2 DE 69029738T2
Authority
DE
Germany
Prior art keywords
double
stranded rna
damage
protection against
shock due
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029738T
Other languages
English (en)
Other versions
DE69029738D1 (de
Inventor
Leo Einck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HEM PHARMACEUTICALS CORP ROCKVILLE MD US
HEM Pharmaceuticals Corp
Original Assignee
HEM PHARMACEUTICALS CORP ROCKVILLE MD US
HEM Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HEM PHARMACEUTICALS CORP ROCKVILLE MD US, HEM Pharmaceuticals Corp filed Critical HEM PHARMACEUTICALS CORP ROCKVILLE MD US
Application granted granted Critical
Publication of DE69029738D1 publication Critical patent/DE69029738D1/de
Publication of DE69029738T2 publication Critical patent/DE69029738T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
DE69029738T 1989-10-11 1990-10-09 Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's Expired - Fee Related DE69029738T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41966389A 1989-10-11 1989-10-11
US57452490A 1990-08-28 1990-08-28
PCT/US1990/005816 WO1991005560A1 (en) 1989-10-11 1990-10-09 PROTECTION FROM SHOCK SUBSEQUENT TO INJURY BY DOUBLE-STRANDED RNAs

Publications (2)

Publication Number Publication Date
DE69029738D1 DE69029738D1 (de) 1997-02-27
DE69029738T2 true DE69029738T2 (de) 1997-08-14

Family

ID=27024574

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029738T Expired - Fee Related DE69029738T2 (de) 1989-10-11 1990-10-09 Schutz gegen schock infolge einer schädigung durch doppelsträngige rna's

Country Status (12)

Country Link
EP (1) EP0495919B1 (de)
JP (1) JP3150967B2 (de)
CN (1) CN1056421A (de)
AT (1) ATE147630T1 (de)
AU (2) AU6740590A (de)
BR (1) BR9007741A (de)
DE (1) DE69029738T2 (de)
HU (1) HUT65404A (de)
IE (1) IE903622A1 (de)
NZ (1) NZ235636A (de)
TW (1) TW206154B (de)
WO (1) WO1991005560A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4409245B2 (ja) * 2003-10-20 2010-02-03 株式会社荏原製作所 耐食性及び耐摩耗性を有する被覆用合金を用いた装置
WO2008014979A2 (en) 2006-07-31 2008-02-07 Curevac Gmbh NUCLEIC ACID OF FORMULA (I): GIXmGn, OR (II): CIXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT
WO2009030254A1 (en) 2007-09-04 2009-03-12 Curevac Gmbh Complexes of rna and cationic peptides for transfection and for immunostimulation
AU2009210266B2 (en) 2008-01-31 2015-01-29 CureVac SE Nucleic acids comprising formula (NuGlXmGmGnNv)a and derivatives thereof as an immunostimulating agents/adjuvants
WO2010037408A1 (en) 2008-09-30 2010-04-08 Curevac Gmbh Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
US20110053829A1 (en) 2009-09-03 2011-03-03 Curevac Gmbh Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
AU2011285200B2 (en) 2010-07-30 2014-08-21 CureVac SE Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
WO2013113326A1 (en) 2012-01-31 2013-08-08 Curevac Gmbh Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
SG10201801431TA (en) 2013-08-21 2018-04-27 Curevac Ag Respiratory syncytial virus (rsv) vaccine
CA2936286A1 (en) 2014-04-01 2015-10-08 Curevac Ag Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1916332A1 (de) * 1969-03-29 1970-10-08 Bayer Ag Xenologe Nucleinsaeuren als immunsupressive Wirkstoffe
DE2046506A1 (en) * 1970-09-21 1972-03-23 Brendel, Walter, Prof. Dr.; Seinfeld, Hugo; 8000 München Xenologous nucleic acids as immunosupressors - for extending the survival time of transplantates
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)
IL86863A0 (en) * 1987-07-03 1988-11-30 Nippon Shinyaku Co Ltd Nucleic acid derivatives
AU1820588A (en) * 1987-07-17 1989-01-19 Hem Research, Inc. Double-stranded rna correction of abnormalities in circulating immune complexes and monocyte function
AU1820388A (en) * 1987-07-17 1989-01-19 Hem Research, Inc. Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles
IE72103B1 (en) * 1987-08-12 1997-03-12 Hem Res Inc Promotion of host defense by systemic dsRNA treatment
EP0306347B1 (de) * 1987-09-04 1995-05-10 Hem Pharmaceuticals Corp. Diagnose von Mangelzuständen doppelsträngiger RNS

Also Published As

Publication number Publication date
DE69029738D1 (de) 1997-02-27
AU6740590A (en) 1991-05-16
EP0495919A4 (en) 1993-03-03
AU678250B2 (en) 1997-05-22
JPH05500960A (ja) 1993-02-25
EP0495919A1 (de) 1992-07-29
WO1991005560A1 (en) 1991-05-02
IE903622A1 (en) 1991-04-24
EP0495919B1 (de) 1997-01-15
CN1056421A (zh) 1991-11-27
ATE147630T1 (de) 1997-02-15
AU6751294A (en) 1994-12-08
JP3150967B2 (ja) 2001-03-26
HUT65404A (en) 1994-06-28
BR9007741A (pt) 1992-08-11
NZ235636A (en) 1997-02-24
HU9201197D0 (en) 1992-08-28
TW206154B (de) 1993-05-21

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Legal Events

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8339 Ceased/non-payment of the annual fee