CA2060490A1 - Protection from shock subsequent to injury by double-stranded rnas - Google Patents

Protection from shock subsequent to injury by double-stranded rnas

Info

Publication number
CA2060490A1
CA2060490A1 CA002060490A CA2060490A CA2060490A1 CA 2060490 A1 CA2060490 A1 CA 2060490A1 CA 002060490 A CA002060490 A CA 002060490A CA 2060490 A CA2060490 A CA 2060490A CA 2060490 A1 CA2060490 A1 CA 2060490A1
Authority
CA
Canada
Prior art keywords
injury
double
protection
stranded rnas
dsrna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002060490A
Other languages
French (fr)
Other versions
CA2060490C (en
Inventor
Leo Einck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hem Research Inc
Original Assignee
Hem Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Research Inc filed Critical Hem Research Inc
Priority to CA002060490A priority Critical patent/CA2060490C/en
Publication of CA2060490A1 publication Critical patent/CA2060490A1/en
Application granted granted Critical
Publication of CA2060490C publication Critical patent/CA2060490C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention details the use of double stranded RNA (dsRNA) for reactivation of natural defense systems within human cells, tissues and organs reduced to inadequate function subsequent to injury. Specific treatments for acquired immune deficient states are described. dsRNA stimulates the release of an immune lymphokine, tumor necrosis factor (TNF) and protects against the toxic effects associated with increased TNF levels.
CA002060490A 1992-01-31 1992-01-31 Protection from shock subsequent to injury by double-stranded rnas Expired - Fee Related CA2060490C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002060490A CA2060490C (en) 1992-01-31 1992-01-31 Protection from shock subsequent to injury by double-stranded rnas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002060490A CA2060490C (en) 1992-01-31 1992-01-31 Protection from shock subsequent to injury by double-stranded rnas

Publications (2)

Publication Number Publication Date
CA2060490A1 true CA2060490A1 (en) 1993-08-01
CA2060490C CA2060490C (en) 2002-07-30

Family

ID=4149195

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002060490A Expired - Fee Related CA2060490C (en) 1992-01-31 1992-01-31 Protection from shock subsequent to injury by double-stranded rnas

Country Status (1)

Country Link
CA (1) CA2060490C (en)

Also Published As

Publication number Publication date
CA2060490C (en) 2002-07-30

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