DE69021296T2 - Salze von optisch aktiven 4-Hydroxy-8-(3-niederalkoxy-4-phenylsulfonylphenyl)pyrazolo [1,5-a]-1,3,5-triazinen und Verfahren zu ihrer Herstellung. - Google Patents

Salze von optisch aktiven 4-Hydroxy-8-(3-niederalkoxy-4-phenylsulfonylphenyl)pyrazolo [1,5-a]-1,3,5-triazinen und Verfahren zu ihrer Herstellung.

Info

Publication number
DE69021296T2
DE69021296T2 DE69021296T DE69021296T DE69021296T2 DE 69021296 T2 DE69021296 T2 DE 69021296T2 DE 69021296 T DE69021296 T DE 69021296T DE 69021296 T DE69021296 T DE 69021296T DE 69021296 T2 DE69021296 T2 DE 69021296T2
Authority
DE
Germany
Prior art keywords
phenylsulfonylphenyl
triazines
pyrazolo
hydroxy
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69021296T
Other languages
English (en)
Other versions
DE69021296D1 (de
Inventor
Kinji Hashimoto
Masatoshi Inai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69021296D1 publication Critical patent/DE69021296D1/de
Publication of DE69021296T2 publication Critical patent/DE69021296T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69021296T 1989-08-25 1990-08-21 Salze von optisch aktiven 4-Hydroxy-8-(3-niederalkoxy-4-phenylsulfonylphenyl)pyrazolo [1,5-a]-1,3,5-triazinen und Verfahren zu ihrer Herstellung. Expired - Fee Related DE69021296T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21918189 1989-08-25
JP2179852A JP2691317B2 (ja) 1989-08-25 1990-07-06 ４―ヒドロキシ―８―（３―低級アルコキシ―４―フェニルスルフィニルフェニル）ピラゾロ〔１，５―ａ〕―１，３，５―トリアジン光学活性体の塩類及びその製造方法

Publications (2)

Publication Number Publication Date
DE69021296D1 DE69021296D1 (de) 1995-09-07
DE69021296T2 true DE69021296T2 (de) 1996-02-01

Family

ID=26499580

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021296T Expired - Fee Related DE69021296T2 (de) 1989-08-25 1990-08-21 Salze von optisch aktiven 4-Hydroxy-8-(3-niederalkoxy-4-phenylsulfonylphenyl)pyrazolo [1,5-a]-1,3,5-triazinen und Verfahren zu ihrer Herstellung.

Country Status (10)

Country Link
US (1) US5137887A (de)
EP (1) EP0414200B1 (de)
JP (1) JP2691317B2 (de)
KR (1) KR960002851B1 (de)
CN (1) CN1028528C (de)
AU (1) AU630489B2 (de)
CA (1) CA2023430C (de)
DE (1) DE69021296T2 (de)
DK (1) DK0414200T3 (de)
ES (1) ES2075860T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420128A (en) * 1990-10-09 1995-05-30 Otsuka Pharmaceutical Co., Ltd. Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor
DE69307999T2 (de) * 1992-11-27 1997-08-14 Sumitomo Spec Metals Herstellungsverfahren für einen auf Seltenerd-Eisen-Stickstoff basierter Dauermagnet
PL195762B1 (pl) * 1996-07-24 2007-10-31 Bristol Myers Squibb Pharma Co Związki [1,5-a]pirazolo-1,3,5-triazynowe, środek farmaceutyczny i zastosowanie związków [1,5-a]pirazolo-1,3,5-triazynowych do wytwarzania leku
US6124289A (en) 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
US6191131B1 (en) 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
US7094782B1 (en) 1996-07-24 2006-08-22 Bristol-Myers Squibb Company Azolo triazines and pyrimidines
US6313124B1 (en) 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
AU4331500A (en) * 1999-04-06 2000-10-23 Du Pont Pharmaceuticals Company Pyrazolotriazines as crf antagonists
WO2000059908A2 (en) 1999-04-06 2000-10-12 Du Pont Pharmaceuticals Company Pyrazolopyrimidines as crf antagonists
MXPA02002111A (es) * 1999-08-27 2002-10-31 Abbott Lab Compuestos de sulfonilfenilpirazol utiles como inhibidores de cox-2.
US6630476B2 (en) 2000-07-07 2003-10-07 Bristol-Myers Squibb Pharma Company Pyrrolo [3,4-d] pyrimidines as corticotropin releasing factor (CRF) antagonists
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7208596B2 (en) * 2003-11-25 2007-04-24 Bristol-Myers Squibb Pharma Company Processes for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof
US7153961B2 (en) * 2003-11-25 2006-12-26 Bristol-Myers Squibb Pharma Co. Salt and crystalline form thereof of a corticotropin releasing factor receptor antagonist
JP4914210B2 (ja) * 2004-06-14 2012-04-11 日本ケミファ株式会社 縮合ピリミジン誘導体、及びキサンチンオキシダーゼ阻害剤
US20090149452A1 (en) * 2005-07-01 2009-06-11 Nippon Chemiphar Co., Ltd. Xanthine oxidase inhibitor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824834A (en) * 1986-10-31 1989-04-25 Otsuka Pharmaceutical Company, Limited Pyrazolotriazine compounds

Also Published As

Publication number Publication date
CA2023430C (en) 1997-11-11
EP0414200B1 (de) 1995-08-02
KR910004623A (ko) 1991-03-29
CN1049664A (zh) 1991-03-06
AU630489B2 (en) 1992-10-29
AU6098590A (en) 1991-02-28
US5137887A (en) 1992-08-11
KR960002851B1 (ko) 1996-02-27
CN1028528C (zh) 1995-05-24
JPH03163082A (ja) 1991-07-15
EP0414200A3 (en) 1991-11-13
EP0414200A2 (de) 1991-02-27
JP2691317B2 (ja) 1997-12-17
DK0414200T3 (da) 1995-12-27
CA2023430A1 (en) 1991-02-26
ES2075860T3 (es) 1995-10-16
DE69021296D1 (de) 1995-09-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee