DE69020676T2 - Tricyclische Carbapenemverbindungen. - Google Patents

Tricyclische Carbapenemverbindungen.

Info

Publication number
DE69020676T2
DE69020676T2 DE69020676T DE69020676T DE69020676T2 DE 69020676 T2 DE69020676 T2 DE 69020676T2 DE 69020676 T DE69020676 T DE 69020676T DE 69020676 T DE69020676 T DE 69020676T DE 69020676 T2 DE69020676 T2 DE 69020676T2
Authority
DE
Germany
Prior art keywords
carbapenem compounds
substituted
tricyclic carbapenem
tricyclic
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69020676T
Other languages
English (en)
Other versions
DE69020676D1 (de
Inventor
Michiyuki Sendai
Tetsuo Miwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69020676D1 publication Critical patent/DE69020676D1/de
Publication of DE69020676T2 publication Critical patent/DE69020676T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D497/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
DE69020676T 1989-10-11 1990-10-09 Tricyclische Carbapenemverbindungen. Expired - Fee Related DE69020676T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26434589 1989-10-11
JP17711890 1990-07-03

Publications (2)

Publication Number Publication Date
DE69020676D1 DE69020676D1 (de) 1995-08-10
DE69020676T2 true DE69020676T2 (de) 1995-12-14

Family

ID=26497770

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69020676T Expired - Fee Related DE69020676T2 (de) 1989-10-11 1990-10-09 Tricyclische Carbapenemverbindungen.

Country Status (10)

Country Link
US (1) US5393751A (de)
EP (1) EP0422596B1 (de)
KR (1) KR910007935A (de)
AT (1) ATE124699T1 (de)
AU (1) AU636913B2 (de)
CA (1) CA2027237A1 (de)
DE (1) DE69020676T2 (de)
HU (1) HU210141B (de)
IE (1) IE903586A1 (de)
NO (1) NO904377L (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ285778B6 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
GB9015485D0 (en) * 1990-07-13 1990-08-29 Glaxo Spa Heterocyclic derivatives
AP238A (en) * 1990-08-21 1993-02-04 Glaxo Spa Heterocyclic compounds.
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104832D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104769D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
EP0507313A1 (de) * 1991-04-05 1992-10-07 Takeda Chemical Industries, Ltd. Polycyclische Carbapenem-Verbindungen, ihre Herstellung und Verwendung
TW198035B (de) * 1991-05-29 1993-01-11 Hoechst Ag
GB9218240D0 (en) * 1992-08-27 1992-10-14 Glaxo Spa Heterocyclic compounds
GB9218781D0 (en) * 1992-09-04 1992-10-21 Glaxo Spa Heterocyclic derivatives
GB9305806D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical compounds
GB9305805D0 (en) * 1993-03-20 1993-05-05 Glaxo Spa Chemical process
US5372993A (en) * 1993-06-10 1994-12-13 Merck & Co., Inc. Bridged carbapenem compounds, compositions containing such compounds and methods of use
US5374630A (en) * 1993-06-10 1994-12-20 Merck & Co., Inc. Bridged carbapenem antibacterial compounds
US5384317A (en) * 1993-08-02 1995-01-24 Merck & Co., Inc. Bridged biphenyl carbapenem compounds, compositions containing such compounds and methods of use
US5401735A (en) * 1993-08-02 1995-03-28 Merck & Co., Inc. Bridged biphenyl carbapenem antibacterial compounds
US20020147333A1 (en) 1993-10-29 2002-10-10 Smithkline Beecham P.L.C. 2-(pyrazol-3-yl)carbapenem derivatives
GB9406074D0 (en) * 1994-03-26 1994-05-18 Glaxo Spa Chemical process
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
AU682287B2 (en) * 1995-05-10 1997-09-25 Morton International, Inc. Latent mercaptans as multi-functional additives for halogen-containing polymer compositions
AU5985596A (en) * 1995-05-31 1996-12-18 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6410775B1 (en) * 1995-06-07 2002-06-25 La Jolla Pharmaceutical Company APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
GB9516118D0 (en) * 1995-08-05 1995-10-04 Glaxo Spa Chemical process
GB9623684D0 (en) * 1996-11-14 1997-01-08 Glaxo Wellcome Spa Chemical compounds
US6531466B2 (en) 1996-11-14 2003-03-11 Glaxosmithkline Spa Tricyclic carbapenem compounds
JPH10168057A (ja) * 1996-12-12 1998-06-23 Takasago Internatl Corp シクロヘキシルアゼチジノン誘導体の製造法
SI9600371B (sl) * 1996-12-18 2005-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Etilidenski derivati tricikličnih karbapenemov
TW498096B (en) * 1997-07-09 2002-08-11 Morton Int Inc Stabilizer composition comprising a blocked mercaptan and polymer composition comprising said stabilizer composition
AU716724B2 (en) * 1998-03-26 2000-03-02 Morton International, Inc. A latent mercaptan as a heat stabilizer
KR200450569Y1 (ko) * 2008-03-03 2010-10-12 전오근 회전하는 갑판이 구비되며 돛의 양력을 이용하여 항주하는레저기구

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600713A (en) * 1979-12-03 1986-07-15 Merck & Co., Inc. 1-, 6- and 2-substituted-1-carba-2-penem-3-carboxylic acids
US4374848A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-(1-Hydroxyethyl)cyclonocardicin
DE68929227T2 (de) * 1988-10-24 2001-05-31 Procter & Gamble Pharma Antimikrobielle Quinolonyllactamester
CZ285778B6 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem

Also Published As

Publication number Publication date
HU906402D0 (en) 1991-04-29
HUT56370A (en) 1991-08-28
NO904377D0 (no) 1990-10-10
HU210141B (en) 1995-02-28
ATE124699T1 (de) 1995-07-15
EP0422596A3 (en) 1992-03-11
US5393751A (en) 1995-02-28
AU636913B2 (en) 1993-05-13
NO904377L (no) 1991-04-12
AU6379290A (en) 1991-04-18
EP0422596A2 (de) 1991-04-17
CA2027237A1 (en) 1991-04-12
DE69020676D1 (de) 1995-08-10
JPH04178389A (ja) 1992-06-25
IE903586A1 (en) 1991-04-24
KR910007935A (ko) 1991-05-30
EP0422596B1 (de) 1995-07-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee