DE69017144T2 - Vorrichtung zum Zählen und zur Bestimmung mindestens einer Leukozytensubpopulation. - Google Patents

Vorrichtung zum Zählen und zur Bestimmung mindestens einer Leukozytensubpopulation.

Info

Publication number
DE69017144T2
DE69017144T2 DE69017144T DE69017144T DE69017144T2 DE 69017144 T2 DE69017144 T2 DE 69017144T2 DE 69017144 T DE69017144 T DE 69017144T DE 69017144 T DE69017144 T DE 69017144T DE 69017144 T2 DE69017144 T2 DE 69017144T2
Authority
DE
Germany
Prior art keywords
counting
determining
electrodes
sample
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69017144T
Other languages
English (en)
Other versions
DE69017144D1 (de
Inventor
Didier Lefevre
Henri Champseix
Serge Champseix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ABX SA
Original Assignee
ABX SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ABX SA filed Critical ABX SA
Application granted granted Critical
Publication of DE69017144D1 publication Critical patent/DE69017144D1/de
Publication of DE69017144T2 publication Critical patent/DE69017144T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/34—Processes using foam culture
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/016—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1024—Counting particles by non-optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1413—Hydrodynamic focussing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69017144T 1989-10-27 1990-10-25 Vorrichtung zum Zählen und zur Bestimmung mindestens einer Leukozytensubpopulation. Expired - Fee Related DE69017144T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8914120A FR2653885B1 (fr) 1989-10-27 1989-10-27 Appareil pour le comptage et la determination d'au moins une sous-population leucocytaire.

Publications (2)

Publication Number Publication Date
DE69017144D1 DE69017144D1 (de) 1995-03-30
DE69017144T2 true DE69017144T2 (de) 1995-06-22

Family

ID=9386856

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69017144T Expired - Fee Related DE69017144T2 (de) 1989-10-27 1990-10-25 Vorrichtung zum Zählen und zur Bestimmung mindestens einer Leukozytensubpopulation.

Country Status (17)

Country Link
US (1) US5138181A (de)
EP (1) EP0425381B1 (de)
JP (1) JP3069795B2 (de)
KR (1) KR0164208B1 (de)
AT (1) ATE118888T1 (de)
AU (1) AU628679B2 (de)
CA (1) CA2028474C (de)
DE (1) DE69017144T2 (de)
DK (1) DK0425381T3 (de)
ES (1) ES2071061T3 (de)
FI (1) FI102324B1 (de)
FR (1) FR2653885B1 (de)
HK (1) HK53796A (de)
IE (1) IE67378B1 (de)
NO (1) NO312487B1 (de)
PT (1) PT95709B (de)
ZA (1) ZA908601B (de)

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JP3052665B2 (ja) * 1993-01-26 2000-06-19 株式会社日立製作所 フローセル装置
US5601234A (en) * 1994-08-01 1997-02-11 Abbott Laboratories Fluid nozzle and method of introducing a fluid
US5530540A (en) * 1994-08-03 1996-06-25 Wyatt Technology Corporation Light scattering measurement cell for very small volumes
FR2733835B1 (fr) * 1995-05-03 1997-07-18 Hycel Groupe Lisabio Procede et dispositif de detection du point de lyse de globules rouges
FR2734636B1 (fr) * 1995-05-24 1997-07-11 Abx Sa Dispositif d'inspection optique d'un fluide, notamment pour analyses hematologiques
FR2734637B1 (fr) * 1995-05-24 1997-08-14 Abx Sa Dispositif d'inspection optique d'un fluide, notamment pour analyses hematologiques
JP3587607B2 (ja) * 1995-12-22 2004-11-10 シスメックス株式会社 粒子測定装置およびその方法
US6819411B1 (en) 1997-01-31 2004-11-16 Xy, Inc. Optical apparatus
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
KR100346118B1 (ko) * 1998-07-13 2002-10-25 삼성전자 주식회사 하드디스크드라이브에서커버의전기적노이즈제거장치및방법
US6473171B1 (en) * 1999-01-15 2002-10-29 Coors Brewing Company Biocompatible apparatus for ultrasensitive and rapid detection of contaminants in liquids
US6507400B1 (en) 1999-02-27 2003-01-14 Mwi, Inc. Optical system for multi-part differential particle discrimination and an apparatus using the same
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US6646742B1 (en) 2000-02-19 2003-11-11 Mwi, Inc. Optical device and method for multi-angle laser light scatter
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
BRPI0115792B1 (pt) 2000-11-29 2020-05-05 Colorado State Univ sistema para separação de espermatozóides congelados/descongelados em populações portadoras de cromossomo-x e portadoras de cromossomo-y
CA2532376C (en) 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
AU2003265471B2 (en) 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
US8323984B2 (en) * 2002-12-19 2012-12-04 Beckman Coulter, Inc. Method and apparatus for mixing blood samples for cell analysis
CN102818761B (zh) 2003-03-28 2015-07-01 英格朗公司 用于分拣颗粒和提供性别分拣的动物精子的设备、方法和程序
DE10320870A1 (de) * 2003-05-09 2004-12-09 Evotec Technologies Gmbh Partikelinjektor für einen Zellsortierer
AU2004242121B2 (en) 2003-05-15 2010-06-24 Xy, Llc. Efficient haploid cell sorting for flow cytometer systems
EP1729789A2 (de) 2004-03-29 2006-12-13 Monsanto Technology, LLC Spermasuspensionen zur verwendung bei der befruchtung
US7833147B2 (en) 2004-07-22 2010-11-16 Inguran, LLC. Process for enriching a population of sperm cells
FR2878032B1 (fr) * 2004-11-18 2007-03-02 Horiba Abx Sa Sa Dispositif d'inspection d'un fluide par illumination uniforme au moyen d'un guide de lumiere conforme
US7355696B2 (en) 2005-02-01 2008-04-08 Arryx, Inc Method and apparatus for sorting cells
US7580120B2 (en) * 2005-04-07 2009-08-25 Sysmex Corporation Blood analyzer, sample analyzer, and flow cytometer
WO2008061058A2 (en) * 2006-11-10 2008-05-22 Luminex Corporation Flow cytometer and fluidic line assembly with multiple injection needles
US7804594B2 (en) * 2006-12-29 2010-09-28 Abbott Laboratories, Inc. Method and apparatus for rapidly counting and identifying biological particles in a flow stream
JP4994920B2 (ja) * 2007-02-01 2012-08-08 シスメックス株式会社 検体分析装置
EP3260842B1 (de) * 2007-02-01 2022-04-13 Sysmex Corporation Hämatologischer analysator und verfahren zur analyse einer probe
EP4027130B1 (de) 2007-02-01 2022-11-02 Sysmex Corporation Probenanalysator
US8159670B2 (en) * 2007-11-05 2012-04-17 Abbott Laboratories Method and apparatus for rapidly counting and identifying biological particles in a flow stream
FR2933192B1 (fr) * 2008-06-25 2010-09-17 Horiba Abx Sas Dispositif et procede de mesure electro optique destines a la classification et au comptage d'elements microscopiques.
FR2939199B1 (fr) 2008-12-02 2011-02-11 C2 Diagnostics Procede et dispositif de cytometrie en flux sans fluide de gainage
US8906309B2 (en) * 2009-04-27 2014-12-09 Abbott Laboratories Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer
FR2956207B1 (fr) * 2010-02-10 2012-05-04 Horiba Abx Sas Dispositif et procede de mesures multiparametriques de microparticules dans un fluide
US9097704B2 (en) 2010-05-05 2015-08-04 Abbott Laboratories Method for hematology analysis
FR2971337B1 (fr) 2011-02-04 2013-03-01 Horiba Abx Sas Dispositif et procede de mesures multiparametriques de microparticules dans un fluide
CN103575637B (zh) * 2013-11-12 2016-02-10 桂林优利特医疗电子有限公司 一种鞘流阻抗、光学同步计数装置
FR3022998B1 (fr) * 2014-06-30 2016-07-15 Alain Rousseau Techniques & Innovations Arteion Systeme et ensemble de cytometrie en flux, dispositif d’analyse comprenant un tel ensemble de cytometrie et ensemble comprenant un tel systeme de cytometrie
FR3034198B1 (fr) 2015-03-26 2019-05-31 C2 Diagnostics Appareil hydrofocus a solution d'analyse unique
FR3034520B1 (fr) 2015-04-02 2020-02-14 Horiba Abx Sas Dispositif de comptage de particules
FR3068469B1 (fr) * 2017-06-28 2020-09-11 Diagdev Cuve de mesure pour le denombrement et/ou la caracterisation de cellules
FR3106408A1 (fr) 2020-01-17 2021-07-23 Horiba Abx Sas Dispositif électro-optique de mesures en flux
FR3138211A1 (fr) 2022-07-25 2024-01-26 Horiba Abx Sas Dispositif pour le comptage et la différenciation de particules d’un flux d’échantillon

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US3781112A (en) * 1972-12-15 1973-12-25 Technicon Instr Method and apparatus for analysis of leukocytes using light scattered by each leukocyte at absorbing and non-absorbing wavelength
DE2943116C2 (de) * 1979-10-25 1986-06-19 Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München Einrichtung zur durchflußcytometrischen Reaktions- und/oder Diffusionsmessung
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JPS59184841A (ja) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− サンプル中の白血球のサブクラスを識別する方法および装置
FR2566543B1 (fr) * 1984-06-20 1988-02-26 Commissariat Energie Atomique Dispositif optique a rendement de collection eleve et cytofluorimetre en faisant application
JPS63262565A (ja) * 1987-04-20 1988-10-28 Hitachi Ltd フロ−セル
FR2621123B1 (fr) * 1987-09-30 1989-12-01 Commissariat Energie Atomique Procede de fabrication d'un dispositif d'analyse optique d'un flux de microparticules et application a la fabrication d'un cytofluorimetre
US5030002A (en) * 1989-08-11 1991-07-09 Becton, Dickinson And Company Method and apparatus for sorting particles with a moving catcher tube

Also Published As

Publication number Publication date
ATE118888T1 (de) 1995-03-15
EP0425381A1 (de) 1991-05-02
KR910007483A (ko) 1991-05-30
JP3069795B2 (ja) 2000-07-24
DK0425381T3 (da) 1995-05-01
ZA908601B (en) 1991-08-28
ES2071061T3 (es) 1995-06-16
AU628679B2 (en) 1992-09-17
NO904640L (no) 1991-04-29
FI102324B (fi) 1998-11-13
CA2028474A1 (en) 1991-04-28
FI102324B1 (fi) 1998-11-13
AU6550290A (en) 1991-05-02
PT95709B (pt) 1998-07-31
FI905296A0 (fi) 1990-10-26
FR2653885A1 (fr) 1991-05-03
KR0164208B1 (ko) 1999-01-15
CA2028474C (en) 2002-06-11
JPH03170843A (ja) 1991-07-24
NO312487B1 (no) 2002-05-13
DE69017144D1 (de) 1995-03-30
IE903847A1 (en) 1991-05-08
US5138181A (en) 1992-08-11
IE67378B1 (en) 1996-03-20
EP0425381B1 (de) 1995-02-22
HK53796A (en) 1996-04-03
FR2653885B1 (fr) 1994-01-14
NO904640D0 (no) 1990-10-26
PT95709A (pt) 1991-09-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee