DE69015363D1 - Verfahren zur herstellung von methylenbisphosphonsäuren. - Google Patents

Verfahren zur herstellung von methylenbisphosphonsäuren.

Info

Publication number
DE69015363D1
DE69015363D1 DE69015363T DE69015363T DE69015363D1 DE 69015363 D1 DE69015363 D1 DE 69015363D1 DE 69015363 T DE69015363 T DE 69015363T DE 69015363 T DE69015363 T DE 69015363T DE 69015363 D1 DE69015363 D1 DE 69015363D1
Authority
DE
Germany
Prior art keywords
pct
sec
bisphosphonic acids
formula
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69015363T
Other languages
English (en)
Other versions
DE69015363T2 (de
Inventor
Klaus Lampi
Kauko Nieminen
Jarkko Ruohonen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Oy
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8528962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69015363(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Leiras Oy filed Critical Leiras Oy
Application granted granted Critical
Publication of DE69015363D1 publication Critical patent/DE69015363D1/de
Publication of DE69015363T2 publication Critical patent/DE69015363T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Control Of El Displays (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Steroid Compounds (AREA)
DE69015363T 1989-09-08 1990-08-15 Verfahren zur herstellung von methylenbisphosphonsäuren. Expired - Fee Related DE69015363T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI894245A FI83657C (fi) 1989-09-08 1989-09-08 Foerfarande foer framstaellning av metylenbisfosfonsyror.
PCT/FI1990/000197 WO1991003480A1 (en) 1989-09-08 1990-08-15 Process for the preparation of methylenebisphosphonic acids

Publications (2)

Publication Number Publication Date
DE69015363D1 true DE69015363D1 (de) 1995-02-02
DE69015363T2 DE69015363T2 (de) 1995-05-24

Family

ID=8528962

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69015363T Expired - Fee Related DE69015363T2 (de) 1989-09-08 1990-08-15 Verfahren zur herstellung von methylenbisphosphonsäuren.

Country Status (16)

Country Link
US (1) US5237094A (de)
EP (1) EP0490907B1 (de)
JP (1) JP2835651B2 (de)
AT (1) ATE115957T1 (de)
AU (1) AU640884B2 (de)
CA (1) CA2066430C (de)
DE (1) DE69015363T2 (de)
DK (1) DK0490907T3 (de)
ES (1) ES2067040T3 (de)
FI (1) FI83657C (de)
HK (1) HK1007560A1 (de)
NO (1) NO180378C (de)
NZ (1) NZ234965A (de)
RU (1) RU2041230C1 (de)
WO (1) WO1991003480A1 (de)
ZA (1) ZA906720B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903345D0 (sv) * 1999-09-17 1999-09-17 Astra Pharma Prod Novel process
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
GB201200868D0 (en) 2012-01-19 2012-02-29 Depuy Int Ltd Bone filler composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA777769A (en) * 1963-03-18 1968-02-06 H. Roy Clarence Substituted methylene diphosphonic acid compounds and detergent compositions
US3683080A (en) 1970-08-28 1972-08-08 Procter & Gamble Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue
DE2229087B2 (de) * 1972-06-15 1977-02-10 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von phosphon- und phosphinsaeuren durch verseifung von phosphon- und phosphinsaeureestern
DE2813121A1 (de) 1977-03-29 1978-10-12 Procter & Gamble Verwendung von dichlormethan-diphosphonatverbindungen bei der bekaempfung von collagen-erkrankungen und zur wundheilung
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1200462B (it) * 1985-04-30 1989-01-18 Gentili Ist Spa Procedimento d'idrolisi degli esteri di acidi metilendifosfonici sostituiti
US4902679A (en) * 1985-12-13 1990-02-20 Norwich Eaton Pharmaceuticals, Inc. Methods of treating diseases with certain geminal diphosphonates

Also Published As

Publication number Publication date
ZA906720B (en) 1991-06-26
FI894245A0 (fi) 1989-09-08
DK0490907T3 (da) 1995-05-08
FI83657C (fi) 1991-08-12
HK1007560A1 (en) 1999-04-16
CA2066430A1 (en) 1991-03-09
JPH05504943A (ja) 1993-07-29
FI83657B (fi) 1991-04-30
EP0490907B1 (de) 1994-12-21
EP0490907A1 (de) 1992-06-24
WO1991003480A1 (en) 1991-03-21
NO180378B (no) 1996-12-30
JP2835651B2 (ja) 1998-12-14
DE69015363T2 (de) 1995-05-24
ATE115957T1 (de) 1995-01-15
ES2067040T3 (es) 1995-03-16
US5237094A (en) 1993-08-17
NO920892L (no) 1992-03-06
NO920892D0 (no) 1992-03-06
CA2066430C (en) 1999-02-02
RU2041230C1 (ru) 1995-08-09
AU6158290A (en) 1991-04-08
FI894245A (fi) 1991-03-09
NO180378C (no) 1997-04-09
NZ234965A (en) 1991-09-25
AU640884B2 (en) 1993-09-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings
8339 Ceased/non-payment of the annual fee