DE69013314T2 - Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol. - Google Patents

Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol.

Info

Publication number
DE69013314T2
DE69013314T2 DE69013314T DE69013314T DE69013314T2 DE 69013314 T2 DE69013314 T2 DE 69013314T2 DE 69013314 T DE69013314 T DE 69013314T DE 69013314 T DE69013314 T DE 69013314T DE 69013314 T2 DE69013314 T2 DE 69013314T2
Authority
DE
Germany
Prior art keywords
sugar alcohol
uniformly dispersed
crystalline sugar
alcohol containing
dispersed particulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69013314T
Other languages
English (en)
Other versions
DE69013314D1 (de
Inventor
James Wix Duross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SPI Polyols Inc
Original Assignee
ICI Americas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23751666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69013314(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ICI Americas Inc filed Critical ICI Americas Inc
Publication of DE69013314D1 publication Critical patent/DE69013314D1/de
Application granted granted Critical
Publication of DE69013314T2 publication Critical patent/DE69013314T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69013314T 1989-11-22 1990-11-22 Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol. Revoked DE69013314T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/441,131 US5075291A (en) 1989-11-22 1989-11-22 Crystalline sugar alcohol containing uniformly dispersed particulate pharmaceutical compound

Publications (2)

Publication Number Publication Date
DE69013314D1 DE69013314D1 (de) 1994-11-17
DE69013314T2 true DE69013314T2 (de) 1995-02-16

Family

ID=23751666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69013314T Revoked DE69013314T2 (de) 1989-11-22 1990-11-22 Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol.

Country Status (14)

Country Link
US (1) US5075291A (de)
EP (1) EP0435450B1 (de)
JP (1) JP3307925B2 (de)
AT (1) ATE112676T1 (de)
AU (1) AU638074B2 (de)
CA (1) CA2030670C (de)
DE (1) DE69013314T2 (de)
ES (1) ES2065499T3 (de)
FI (1) FI95657C (de)
IE (1) IE904219A1 (de)
NO (1) NO905075L (de)
PT (1) PT95964A (de)
TW (1) TW217386B (de)
ZA (1) ZA909313B (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158789A (en) * 1991-08-09 1992-10-27 Ici Americas Inc. Melt cocrystallized sorbitol/xylitol compositions
US5139795A (en) * 1991-08-09 1992-08-18 Ici Americas Inc. Melt crystallized xylitol
JPH069382A (ja) * 1992-04-17 1994-01-18 Takeda Chem Ind Ltd 安定化された固型製剤およびその製造方法
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
US5405623A (en) * 1993-09-22 1995-04-11 Wm. Wrigley Jr. Company Chewing gum compositions and methods for manufacturing same
US5397580A (en) * 1993-10-22 1995-03-14 Wm. Wrigley Jr. Company Continuous gum base manufacture using sequential mixers
US5773053A (en) * 1993-09-24 1998-06-30 Wm. Wrigley Jr. Company Chewing gum base manufacturing process using plurality of softening agents inlets
US5419919A (en) * 1993-10-22 1995-05-30 Wm. Wrigley Jr. Company Continuous gum base manufacture using paddle mixing
US6004589A (en) * 1993-09-24 1999-12-21 Wm. Wrigley Jr. Company Chewing gum base manufacturing process using plurality of filler feed inlet locations
US6086925A (en) * 1993-09-24 2000-07-11 Wm. Wrigley Jr. Company Chewing gum base manufacturing process using plurality of lubricating agents feed inlets
US5543160A (en) * 1994-09-13 1996-08-06 Wm. Wrigley Jr. Company Total chewing gum manufacture using high efficiency continuous mixing
US5549757A (en) * 1994-06-10 1996-08-27 Ingredient Technology Corporation Process for recrystallizing sugar and product thereof
US6586006B2 (en) * 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
WO1996008165A1 (en) * 1994-09-13 1996-03-21 Wm. Wrigley Jr. Company Continuous chewing gum manufacture from base concentrate
JPH10502541A (ja) 1994-09-13 1998-03-10 ダブリューエム リグリー ジュニア カンパニー ガムベースの連続製造方法
DE69506119T2 (de) * 1994-09-15 1999-06-24 Procter & Gamble Orale zusammensetzungen
US5976581A (en) * 1995-09-12 1999-11-02 Wm. Wrigley Jr. Company Continuous chewing gum manufacturing process using rework gum
US5827549A (en) * 1996-02-21 1998-10-27 Wm. Wrigley, Jr. Company Process control system for automated continuous production of chewing gum
US6017565A (en) * 1996-02-21 2000-01-25 Wm. Wrigley Jr. Company Method for automated continuous production of chewing gum
DE19617487A1 (de) † 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
KR100473990B1 (ko) 1997-03-31 2005-03-14 가부시키가이샤 가네보케쇼힝 멜라닌 생성 억제제, 피부 화장료 조성물 및 목욕용제
US5840334A (en) * 1997-08-20 1998-11-24 Fuisz Technologies Ltd. Self-binding shearform compositions
US6123980A (en) * 1997-12-01 2000-09-26 Imperial Sugar Company Preparing granulated sugar blends and products
NZ333474A (en) 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US5948388A (en) * 1998-06-12 1999-09-07 Soft Gel Technologies, Inc. Chewable softgel oral hygiene product
US20020098264A1 (en) * 1998-11-27 2002-07-25 Cherukuri Subraman R. Medicated chewing gum delivery system for nicotine
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
AT407111B (de) * 1998-12-22 2000-12-27 Gergely Dr & Co Zucker- und/oder zuckeralkoholhältiges matrixmaterial und verfahren zu seiner herstellung
WO2000076480A2 (en) * 1999-06-11 2000-12-21 Eli Lilly And Company Pharmaceutical materials and methods for their preparation and use
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
JP4588818B2 (ja) * 1999-09-16 2010-12-01 日本化学機械製造株式会社 錠剤用賦形剤及び錠剤
US6793934B1 (en) 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
US6602912B2 (en) * 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US20070092583A1 (en) * 2003-04-30 2007-04-26 Tim Clarot Cold remedy composition comprising zinc salts
US20070092552A1 (en) * 2003-04-30 2007-04-26 Tim Clarot Chewable lozenge cold remedy composition and method for making same
US20070059358A1 (en) * 2003-07-02 2007-03-15 Tianjin Tasly Pharmaceutical Co., Ltd., China Matrix adjuvants and the drop pills prepared with them
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
AT500101A1 (de) * 2004-02-04 2005-10-15 Tritthart Thomas Verkapselungsprozess
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
MX2007001597A (es) * 2004-08-12 2007-05-23 Reckitt Benckiser Healthcare Granulos que comprenden paracetamol, un farmaco antiinflamatorio no esteroidal y un alcohol de azucar hecho por extrusion por fusion.
WO2006131806A2 (en) * 2005-06-07 2006-12-14 Pfizer Products Inc. Multiparticulates comprising low-solubility drugs and carriers that result in rapid drug release
CA2629904C (en) 2005-11-28 2018-07-10 Imaginot Pty Ltd. Oral therapeutic compound delivery system
EP1832281A1 (de) * 2006-03-10 2007-09-12 Abbott GmbH & Co. KG Verfahren zur Herstellung einer Feststoffdispersion eines aktiven Wirkstoffes
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
AU2008312321A1 (en) * 2007-10-19 2009-04-23 Purdue Research Foundation Solid formulations of crystalline compounds
GB0813709D0 (en) * 2008-07-26 2008-09-03 Univ Dundee Method and product
ES2542238T3 (es) 2009-12-22 2015-08-03 Firmenich S.A. Sistema de administración de principios activos
JP5330320B2 (ja) * 2010-06-09 2013-10-30 日本化学機械製造株式会社 錠剤用賦形剤及び錠剤
DE102010033527A1 (de) 2010-08-05 2012-02-09 Acino Pharma Ag Quetiapin-Tabletten
DE102011115690A1 (de) 2011-10-11 2013-04-11 Acino Pharma Ag Quetiapin enthaltende Formulierungen
US20150080567A1 (en) * 2013-09-04 2015-03-19 Nalas Engineering Services Inc. Method to Produce and Scale-Up Cocrystals and Salts Via Resonant Acoustic Mixing
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
DE102014104676A1 (de) * 2014-04-02 2015-10-08 Heraeus Medical Gmbh Fosfomycin-Zubereitung, ein Verfahren zur Herstellung der Zubereitung und ein die Zubereitung enthaltendes Polymethylmethacrylat-Knochenzementpulver
CN112999181B (zh) * 2019-12-19 2023-11-14 鲁南制药集团股份有限公司 一种富马酸沃诺拉赞片剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200039A (en) * 1962-05-28 1965-08-10 Pfizer & Co C Non-granulated tablets with 20% sorbitol in a particle size of from about 100mu to about 2000mu
US3341415A (en) * 1964-02-12 1967-09-12 Warner Lambert Pharmaceutical Pharmaceutical tablet excipients of solid particles of a binary solid solution of mannitol with a sugar
US4252794A (en) * 1979-12-20 1981-02-24 Ici Americas Inc. Gamma-sorbitol polymorph
US4870059A (en) * 1985-11-27 1989-09-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Dehydration of hydrous matter with anhydrous maltose
JPH0728671B2 (ja) * 1987-08-21 1995-04-05 三菱化学株式会社 チュ−インガムの製造方法
US5017400A (en) * 1988-06-10 1991-05-21 Suomen Xyrofin Oy Non-cariogenic sweetener
US5023092A (en) * 1988-06-16 1991-06-11 Ici Americas Inc. Mannitol having gamma sorbitol polymorph
JPH075624B2 (ja) * 1989-01-31 1995-01-25 東和化成工業株式会社 ラクチトール三水和物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法

Also Published As

Publication number Publication date
FI905781A0 (fi) 1990-11-22
FI905781A (fi) 1991-05-23
JP3307925B2 (ja) 2002-07-29
EP0435450B1 (de) 1994-10-12
CA2030670A1 (en) 1991-05-23
DE69013314D1 (de) 1994-11-17
AU6676990A (en) 1991-05-30
EP0435450A2 (de) 1991-07-03
NO905075D0 (no) 1990-11-22
EP0435450A3 (en) 1991-09-04
PT95964A (pt) 1991-10-15
IE904219A1 (en) 1991-05-22
ZA909313B (en) 1991-10-30
AU638074B2 (en) 1993-06-17
TW217386B (de) 1993-12-11
NO905075L (no) 1991-05-23
JPH03209336A (ja) 1991-09-12
ES2065499T3 (es) 1995-02-16
FI95657B (fi) 1995-11-30
FI95657C (fi) 1996-03-11
ATE112676T1 (de) 1994-10-15
CA2030670C (en) 2000-08-08
US5075291A (en) 1991-12-24

Similar Documents

Publication Publication Date Title
DE69013314D1 (de) Einen gleichmässig dispergierten partikulären Arzneistoff enthaltender kristalliner Zuckeralkohol.
FI945476A0 (fi) Hitaasti vapautuvat koostumukset ja menetelmä farmaseuttisten koostumusten valmistamiseksi
OA07282A (fr) Composition pharmaceutique lyophilisée contenant de l'interféron procédé pour la préparation et procédé pour sa stabilisation.
HUT50339A (en) Process for producing benzoxazole derivatives and pharmaceutical compositions comprising the compounds
HUT49113A (en) Process for producing 2-/2-hydroxy-3-phenoxy-propyl-amino/-ethyl-phenoxy-methyl-amido derivatives and pharmaceutical compositions containing them as active components
ES2032295T3 (es) Acetaminofeno secado por atomizacion.
RU93045145A (ru) Замещенные производные циклогексана и их применение для лечения заболеваний, содержащее их лекарственное средство
PT84526B (pt) Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno
DK102081A (da) Adjuvans til antibiotikum
DK101981A (da) Adjuvans til antibiotikum
AU438622B2 (en) Optical isomer of alpha-racemate 2 (2 ethyl phenyl 1, 3 dioxo-lan-4 yl)-piperidine its use asan intravenous anesthetic and process for production
AU6600569A (en) Optical isomer of alpha-racemate 2 (2 ethyl phenyl 1, 3 dioxo-lan-4 yl)-piperidine its use asan intravenous anesthetic and process for production

Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: SPI POLYOLS, INC., WILMINGTON, DEL., US

8331 Complete revocation