DE69012141D1 - Ortsspezifische modifikation des candida tropicalis genomes. - Google Patents

Ortsspezifische modifikation des candida tropicalis genomes.

Info

Publication number
DE69012141D1
DE69012141D1 DE69012141T DE69012141T DE69012141D1 DE 69012141 D1 DE69012141 D1 DE 69012141D1 DE 69012141 T DE69012141 T DE 69012141T DE 69012141 T DE69012141 T DE 69012141T DE 69012141 D1 DE69012141 D1 DE 69012141D1
Authority
DE
Germany
Prior art keywords
genomes
location
candida tropicalis
specific modification
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69012141T
Other languages
English (en)
Other versions
DE69012141T2 (de
Inventor
Stephen Picataggio
Kristine Deanda
L Eirich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cognis IP Management GmbH
Original Assignee
Henkel Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Research Corp filed Critical Henkel Research Corp
Application granted granted Critical
Publication of DE69012141D1 publication Critical patent/DE69012141D1/de
Publication of DE69012141T2 publication Critical patent/DE69012141T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/165—Yeast isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/72—Candida
    • C12R2001/74—Candida tropicalis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/921—Candida
    • Y10S435/924—Candida tropicalis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69012141T 1989-11-06 1990-11-06 Ortsspezifische modifikation des candida tropicalis genomes. Expired - Lifetime DE69012141T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/432,091 US5254466A (en) 1989-11-06 1989-11-06 Site-specific modification of the candida tropicals genome
PCT/US1990/006427 WO1991006660A1 (en) 1989-11-06 1990-11-06 Site-specific modification of the candida tropicalis genome

Publications (2)

Publication Number Publication Date
DE69012141D1 true DE69012141D1 (de) 1994-10-06
DE69012141T2 DE69012141T2 (de) 1995-04-06

Family

ID=23714740

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69012141T Expired - Lifetime DE69012141T2 (de) 1989-11-06 1990-11-06 Ortsspezifische modifikation des candida tropicalis genomes.

Country Status (8)

Country Link
US (1) US5254466A (de)
EP (1) EP0499622B1 (de)
JP (1) JP3023984B2 (de)
AU (1) AU6741490A (de)
CA (1) CA2072977A1 (de)
DE (1) DE69012141T2 (de)
WO (1) WO1991006660A1 (de)
ZA (1) ZA908653B (de)

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US6245538B1 (en) 1996-08-28 2001-06-12 Henkel Corporation Process for recovering carboxylic acids from a fermentation broth
EP1273663A3 (de) * 1997-07-21 2004-02-04 E.I. Dupont De Nemours And Company Transformierte Hefestämme und ihre Verwendung zur Herstellung von mono- und di-terminalen aliphatischen Carboxylaten
WO1999004014A2 (en) * 1997-07-21 1999-01-28 E.I. Du Pont De Nemours And Company Transformed yeast strains and their use for the production of monoterminal and diterminal aliphatic carboxylates
US20040146999A1 (en) * 1997-07-21 2004-07-29 E.I. Du Pont De Nemours And Company Transformed yeast strains and their use for the production of monoterminal and diterminal aliphatic carboxylates
JP2002512037A (ja) * 1998-04-20 2002-04-23 フォルスカルパテント イー エスイーデー アクティエボラーグ リグノセルロース加水分解産物の効率の良い発酵のための遺伝子操作された酵母及びその突然変異体
US20030077795A1 (en) * 1999-03-10 2003-04-24 Wilson C. Ron Cytochrome P450 monooxygenase and NADPH Cytochrome P450 oxidoreductase genes and proteins related to the omega hydroxylase complex of candida tropicals and methods relating thereto
US6331420B1 (en) 1998-05-01 2001-12-18 C. Ron Wilson Cytochrome P450 monooxygenase and NADPH cytochrome P450 oxidoreductase genes and proteins related to the omega hydroxylase complex of Candida tropicalis and methods relating thereto
US6004784A (en) * 1998-09-14 1999-12-21 General Electric Co. Fermentation medium and method for producing α, ω -alkanedicarboxylic acids
US6066480A (en) * 1998-09-21 2000-05-23 General Electric Company Method for high specific bioproductivity of α,ω-alkanedicarboxylic acids
EP1148134B1 (de) 1998-10-05 2009-10-28 Cognis IP Management GmbH Cytochrom P450 Monooxygenase Gen und Protein des Omega-Hydroxylase-Komplexes von Candida Tropicalis und darauf bezogene Verfahren
AU6387199A (en) * 1998-10-05 2000-04-26 Cognis Corporation Process for recovering carboxylic acides from a fermentation broth
US6288275B1 (en) * 1999-07-09 2001-09-11 Henkel Corporation Separation and purification of carboxylic acids from fermentation broths
US6376223B1 (en) 1999-08-04 2002-04-23 Cognis Corporation Process for purifying polycarboxylic acids
WO2001021572A1 (en) * 1999-09-22 2001-03-29 Cognis Corporation Purification and recovery of dicarboxylic acids using melt crystallization
CA2386169A1 (en) * 1999-09-30 2001-04-12 Cognis Corporation Improved fermentation process
US6569670B2 (en) * 1999-09-30 2003-05-27 Cognis Corporation Fermentation process
US20020061566A1 (en) * 2000-03-20 2002-05-23 Eirich L. Dudley Biooxidation capabilities of candida sp
US6673613B2 (en) 2000-07-26 2004-01-06 Cognis Corporation Use of CYP52A2A promoter to increase gene expression in yeast
US20020193530A1 (en) * 2001-03-12 2002-12-19 Gates Jeffrey A. Acrylic powder coating resin having low volatility
US7211140B1 (en) 2001-12-14 2007-05-01 Cognis Corporation Low temperature plasticizers for flexible polyvinyl chloride resin applications
AU2003247411A1 (en) * 2002-05-23 2003-12-12 Cognis Corporation NON-REVERTIBLE Beta-OXIDATION BLOCKED CANDIDA TROPICALIS
US20040265980A1 (en) * 2002-08-05 2004-12-30 Yeyan Zhang Use of POX4 promoter to increase gene expression in Candida tropicalis
US7388084B2 (en) * 2002-08-16 2008-06-17 Cognis Corporation Promoter motifs in Candida tropicalis
US6777213B2 (en) * 2002-10-29 2004-08-17 Cognis Corporation Isolation of carboxylic acids from fermentation broth
US7270947B2 (en) * 2003-01-14 2007-09-18 Cognis Corporation Method for controlling biooxidation reactions
US8183190B2 (en) * 2003-08-20 2012-05-22 Cognis Ip Management Gmbh Complex polyol esters with improved performance
FR2879215B1 (fr) * 2004-12-15 2010-08-20 Inst Francais Du Petrole Production d'acides dicarboxyliques par des souches mutantes ameliorees de yarrowia lipolytica
FR2921363B1 (fr) 2007-09-20 2009-11-06 Arkema France Procedes de synthese de diacides gras par metathese de diacides insatures obtenus par fermentation d'acides gras naturels
FR2921362B1 (fr) * 2007-09-20 2012-09-21 Arkema France Procede de synthese d'acides gras omega-insatures
EP2231750A2 (de) * 2007-11-26 2010-09-29 Cognis IP Management GmbH Aus langkettigen dicarbonsäuren hergestellte polyamide und verfahren zur herstellung der polyamide
US8530206B2 (en) * 2008-05-21 2013-09-10 Ecover Coordination Center N.V. Method for the production of medium-chain sophorolipids
FR2932807B1 (fr) 2008-06-20 2011-12-30 Arkema France Polyamide, composition comprenant un tel polyamide et leurs utilisations.
FR2932808B1 (fr) 2008-06-20 2010-08-13 Arkema France Copolyamide, composition comprenant un tel copolyamide et leurs utilisations.
FR2933415B1 (fr) * 2008-07-07 2010-08-13 Arkema France Polyamide, composition comprenant un tel polyamide et leurs utilisations
FR2933696B1 (fr) * 2008-07-10 2010-08-20 Arkema France Procede de synthese d'acides omega-amino-alcanoiques ou de leurs esters a partir d'acides gras naturels.
EP2310517B1 (de) * 2008-07-11 2016-03-16 Institut National De La Recherche Agronomique (INRA) Neue hefestammmutanten mit fähigkeit zur anhäufung grosser lipidmengen
KR20110101198A (ko) 2008-12-12 2011-09-15 이 아이 듀폰 디 네모아 앤드 캄파니 재생 가능 자원으로부터의 선형 다이카르복실산의 제조 방법
FR2941694B1 (fr) 2009-02-05 2011-02-11 Arkema France Procede de synthese d'un omega-aminoacide ou ester a partir d'un acide ou ester gras mono-insature.
US8158391B2 (en) 2009-05-06 2012-04-17 Dna Twopointo, Inc. Production of an α-carboxyl-ω-hydroxy fatty acid using a genetically modified Candida strain
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CN102617320A (zh) * 2012-02-08 2012-08-01 上海凯赛生物技术研发中心有限公司 一种对含长链二元酸盐的反应液进行处理的方法
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US5204252A (en) * 1989-02-08 1993-04-20 Henkel Research Corporation Candida tropicalis transformation system

Also Published As

Publication number Publication date
JPH05501501A (ja) 1993-03-25
ZA908653B (en) 1991-08-28
DE69012141T2 (de) 1995-04-06
EP0499622B1 (de) 1994-08-31
US5254466A (en) 1993-10-19
WO1991006660A1 (en) 1991-05-16
AU6741490A (en) 1991-05-31
CA2072977A1 (en) 1991-05-07
EP0499622A1 (de) 1992-08-26
JP3023984B2 (ja) 2000-03-21

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Owner name: COGNIS CORP. (N.D. GES. D. STAATES DELAWARE), SANT

8327 Change in the person/name/address of the patent owner

Owner name: COGNIS IP MANAGEMENT GMBH, 40589 DUESSELDORF, DE