DE69011410T2 - In einer evaluierten Röhre zentrifugierte Material-Schicht-Messungen. - Google Patents

In einer evaluierten Röhre zentrifugierte Material-Schicht-Messungen.

Info

Publication number
DE69011410T2
DE69011410T2 DE69011410T DE69011410T DE69011410T2 DE 69011410 T2 DE69011410 T2 DE 69011410T2 DE 69011410 T DE69011410 T DE 69011410T DE 69011410 T DE69011410 T DE 69011410T DE 69011410 T2 DE69011410 T2 DE 69011410T2
Authority
DE
Germany
Prior art keywords
centrifuged
evaluated
tube
layer measurements
measurements
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69011410T
Other languages
English (en)
Other versions
DE69011410D1 (de
Inventor
Robert Aaron Levine
Stephen Clark Wardlaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69011410D1 publication Critical patent/DE69011410D1/de
Publication of DE69011410T2 publication Critical patent/DE69011410T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • B01L3/50215Test tubes specially adapted for centrifugation purposes using a float to separate phases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/042Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69011410T 1989-05-24 1990-02-28 In einer evaluierten Röhre zentrifugierte Material-Schicht-Messungen. Expired - Fee Related DE69011410T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35607789A 1989-05-24 1989-05-24

Publications (2)

Publication Number Publication Date
DE69011410D1 DE69011410D1 (de) 1994-09-15
DE69011410T2 true DE69011410T2 (de) 1994-12-15

Family

ID=23400019

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69011410T Expired - Fee Related DE69011410T2 (de) 1989-05-24 1990-02-28 In einer evaluierten Röhre zentrifugierte Material-Schicht-Messungen.

Country Status (15)

Country Link
US (1) US5086784A (de)
EP (1) EP0399151B1 (de)
JP (1) JPH0721492B2 (de)
CN (1) CN1023153C (de)
AR (1) AR242902A1 (de)
AT (1) ATE109643T1 (de)
AU (1) AU620213B2 (de)
BR (1) BR9002418A (de)
CA (1) CA2011100C (de)
DE (1) DE69011410T2 (de)
DK (1) DK0399151T3 (de)
ES (1) ES2057214T3 (de)
FI (2) FI100436B (de)
NO (1) NO179394C (de)
RU (2) RU2052186C1 (de)

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AU644037B2 (en) * 1992-01-21 1993-12-02 Robert A. Levine Constituent layer harvesting from a centrifuged sample in a tube
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US5533518A (en) * 1994-04-22 1996-07-09 Becton, Dickinson And Company Blood collection assembly including mechanical phase separating insert
GB9703185D0 (en) * 1997-02-15 1997-04-02 Thurnall Plc Individual septum capped microtubes
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US5938621A (en) * 1997-09-12 1999-08-17 Becton Dickinson And Company Collection container assembly
US6197523B1 (en) 1997-11-24 2001-03-06 Robert A. Levine Method for the detection, identification, enumeration and confirmation of circulating cancer and/or hematologic progenitor cells in whole blood
US6911315B2 (en) * 1997-11-24 2005-06-28 David L. Rimm Method for the detection, identification, enumeration and confirmation of virally infected cells and other epitopically defined cells in whole blood
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
US20030133845A1 (en) * 2002-01-14 2003-07-17 Eureka Group Identification device for explosives or other materials
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20030205538A1 (en) * 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
AU2003249642A1 (en) 2002-05-24 2003-12-12 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7074577B2 (en) * 2002-10-03 2006-07-11 Battelle Memorial Institute Buffy coat tube and float system and method
US7220593B2 (en) 2002-10-03 2007-05-22 Battelle Memorial Institute Buffy coat separator float system and method
EP2264512B1 (de) * 2004-11-24 2014-06-04 Battelle Memorial Institute Verfahren und Vorrichtung zur Detektion von seltenen Zellen
JP4609323B2 (ja) * 2006-01-06 2011-01-12 ニプロ株式会社 検体採取液容器
JP4609252B2 (ja) * 2005-09-07 2011-01-12 ニプロ株式会社 検体採取液容器
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
WO2008127639A1 (en) 2007-04-12 2008-10-23 Biomet Biologics, Llc Buoy suspension fractionation system
EP2620139B1 (de) 2008-02-27 2016-07-20 Biomet Biologics, LLC Interleukin-1-Rezeptorantagonisten-reiche Lösungen
EP2254991B1 (de) 2008-02-29 2018-08-22 Biomet Manufacturing, LLC System und verfahren zur trennung eines materials
CA2819470C (en) 2008-07-21 2016-05-10 Becton, Dickinson And Company Density phase separation device
JP5385383B2 (ja) 2008-07-21 2014-01-08 ベクトン・ディキンソン・アンド・カンパニー 密度相分離装置
EP2517793B1 (de) 2008-07-21 2013-09-11 Becton, Dickinson and Company Dichtephasentrennvorrichtung
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
BR122021008538B1 (pt) 2009-05-15 2022-05-24 Becton, Dickinson And Company Conjunto de separação para separar uma amostra de fluido em primeira e segunda fases
WO2010148135A2 (en) * 2009-06-16 2010-12-23 Levine Robert A Harvesting target materials from centrifuged suspensions
US9011800B2 (en) * 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US20120016320A1 (en) * 2010-07-13 2012-01-19 Lin Michael T Method and Device for Liquid Delivery
US20120308447A1 (en) * 2011-05-31 2012-12-06 Timothy Alan Abrahamson Tube and float systems for density-based fluid separation
ES2437541B1 (es) * 2012-07-03 2014-11-25 Biotechnology Institute, I Mas D, S.L. Dispositivo para la extracción, el almacenamiento y/o el procesado de sangre u otras sustancias de origen humano o animal, y para la aplicación de compuestos sanguíneos u otros compuestos biológicos
US8984932B2 (en) 2012-07-18 2015-03-24 Theranos, Inc. Rapid measurement of formed blood component sedimentation rate from small sample volumes
SG10201605479QA (en) 2012-07-18 2016-08-30 Theranos Inc Rapid measurement of formed blood component sedimentation rate from small sample volumes
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
WO2014130426A1 (en) 2013-02-21 2014-08-28 Regenerative Sciences, Llc Blood and marrow draw processing devices and methods
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
RU2548787C1 (ru) * 2014-04-09 2015-04-20 Александр Георгиевич Рожков Кювета для исследования коллоидных свойств жидкостных сред организма человека (варианты)
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
ES2593042B1 (es) * 2015-06-03 2017-10-03 Biotechnology Institute, I Mas D, S.L. Dispositivo de recolección de sangre o de un compuesto sanguíneo
RU176274U1 (ru) * 2017-07-10 2018-01-15 Виктор Андреевич Линд Устройство для пробоподготовки крови для определения концентрации глюкозы в плазме крови
US20220088589A1 (en) 2019-01-21 2022-03-24 Eclipse Medcorp, Llc Methods, Systems and Apparatus for Separating Components of a Biological Sample
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Also Published As

Publication number Publication date
AU5017790A (en) 1990-11-29
JPH02311761A (ja) 1990-12-27
CA2011100A1 (en) 1990-11-24
CA2011100C (en) 1996-06-11
CN1023153C (zh) 1993-12-15
ES2057214T3 (es) 1994-10-16
NO179394B (no) 1996-06-24
NO179394C (no) 1996-10-02
DK0399151T3 (da) 1994-10-03
FI902200A0 (fi) 1990-05-02
AR242902A1 (es) 1993-06-30
FI972084A0 (fi) 1997-05-15
CN1047570A (zh) 1990-12-05
NO902289D0 (no) 1990-05-23
EP0399151A1 (de) 1990-11-28
RU2095024C1 (ru) 1997-11-10
EP0399151B1 (de) 1994-08-10
RU2052186C1 (ru) 1996-01-10
RU94024565A (ru) 1996-09-27
AU620213B2 (en) 1992-02-13
FI100436B (fi) 1997-11-28
FI972084A (fi) 1997-05-15
NO902289L (no) 1990-11-26
US5086784A (en) 1992-02-11
ATE109643T1 (de) 1994-08-15
BR9002418A (pt) 1991-08-06
DE69011410D1 (de) 1994-09-15
JPH0721492B2 (ja) 1995-03-08

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee