DE69003693D1 - Verfahren zur Expression von Biotin in Bacillus sphaericus. - Google Patents

Verfahren zur Expression von Biotin in Bacillus sphaericus.

Info

Publication number
DE69003693D1
DE69003693D1 DE90400129T DE69003693T DE69003693D1 DE 69003693 D1 DE69003693 D1 DE 69003693D1 DE 90400129 T DE90400129 T DE 90400129T DE 69003693 T DE69003693 T DE 69003693T DE 69003693 D1 DE69003693 D1 DE 69003693D1
Authority
DE
Germany
Prior art keywords
biotin
expression
bacillus sphaericus
sphaericus
bacillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90400129T
Other languages
English (en)
Other versions
DE69003693T2 (de
Inventor
Denis Speck
Remi Gloeckler
Yves Lemoine
Ikuro Ohsawa
Tugio Kisou
Kouichi Kamogawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Zeon Corp
Original Assignee
Transgene SA
Nippon Zeon Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA, Nippon Zeon Co Ltd filed Critical Transgene SA
Publication of DE69003693D1 publication Critical patent/DE69003693D1/de
Application granted granted Critical
Publication of DE69003693T2 publication Critical patent/DE69003693T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
    • C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE1990603693 1989-01-19 1990-01-17 Verfahren zur Expression von Biotin in Bacillus sphaericus. Expired - Fee Related DE69003693T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8900597A FR2642768B1 (fr) 1989-01-19 1989-01-19 Procede perfectionne pour l'expression de la biotine dans bacillus sphaericus

Publications (2)

Publication Number Publication Date
DE69003693D1 true DE69003693D1 (de) 1993-11-11
DE69003693T2 DE69003693T2 (de) 1994-02-24

Family

ID=9377861

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1990603693 Expired - Fee Related DE69003693T2 (de) 1989-01-19 1990-01-17 Verfahren zur Expression von Biotin in Bacillus sphaericus.

Country Status (4)

Country Link
EP (1) EP0379428B1 (de)
JP (1) JPH03180174A (de)
DE (1) DE69003693T2 (de)
FR (1) FR2642768B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277609B1 (en) 1993-01-06 2001-08-21 Basf Aktiengesellschaft Method to produce biotin
EP0635572A3 (de) 1993-06-25 1995-03-08 Hoffmann La Roche Biotinbiosynthese in Bacillus subtilis.
JP3764166B2 (ja) * 1994-09-28 2006-04-05 ノボザイムス アクティーゼルスカブ 二次代謝産物を産生するための方法
US6361978B1 (en) 1996-05-06 2002-03-26 Roche Vitamins, Inc. Production of biotin

Also Published As

Publication number Publication date
JPH03180174A (ja) 1991-08-06
FR2642768A1 (fr) 1990-08-10
DE69003693T2 (de) 1994-02-24
EP0379428B1 (de) 1993-10-06
FR2642768B1 (fr) 1991-05-17
EP0379428A1 (de) 1990-07-25

Similar Documents

Publication Publication Date Title
DE69019074D1 (de) Verfahren zur Fraktionierung von Plasmaproteinen.
DE69007691D1 (de) Verfahren zur Herstellung von Alkylaluminoxanen.
DE68916523D1 (de) Verfahren zur Vorbehandlung von Kunststoffsubstraten.
DE59003481D1 (de) Verfahren zur formgebenden bearbeitung von werkstücken.
DE3750076D1 (de) Verfahren zur Veränderung der Eigenschften von Halbleitern.
DE69016529D1 (de) Verfahren zur Elektroporation und dafür verwendeter Puffer.
DE69004594D1 (de) Verfahren zur Verbrennung von Kohlenstaub.
DE68912114D1 (de) Verfahren zur Trennung von 1,1-Dichlor-1-fluorethan und 1,1,1,3,3-Pentafluorbutan.
DE3888372D1 (de) Verfahren zur Reinigung von Hexamethyldisiloxan.
DE69003423D1 (de) Verfahren zur Reinigung von 1,1,1,2-Tetrafluorethan.
DE69004229D1 (de) Verfahren zur Reinigung von 1,1-Dichlor-1-fluorethan.
DE58906148D1 (de) Verfahren zur Herstellung von Aminen.
DE69305411D1 (de) Verfahren zur Beseitigung von Mikroorganismen
DE68914485D1 (de) Verfahren zur Metallisierung von Fasergegenständen.
DE59002817D1 (de) Verfahren zur kontinuierlichen Reinigung von Caprolactam.
DE69009952D1 (de) Verfahren zur Verbrennung von feuchten Abfällen.
DE59003282D1 (de) Verfahren zur Herstellung von Dawsonit.
DE69012896D1 (de) Verfahren zur Zersetzung von Chlorfluorkohlenstoffen.
DE59005265D1 (de) Verfahren zur Herstellung von Aminen.
DE3769024D1 (de) Verfahren und vorrichtung zur uebertragung von artikeln.
DE68924225D1 (de) Verfahren zur Erhöhung der Wiederbenetzbarkeit von Textilien.
DE69016382D1 (de) Verfahren zur Herstellung von Polyimiden.
DE3850513D1 (de) Apparat zur Verarbeitung von Briefen.
DE68918000D1 (de) Verfahren zur Entfernung von Rückständen.
DE68915350D1 (de) Verfahren zur enzymatischen Auflösung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee