DE68915350D1 - Verfahren zur enzymatischen Auflösung. - Google Patents

Verfahren zur enzymatischen Auflösung.

Info

Publication number
DE68915350D1
DE68915350D1 DE68915350T DE68915350T DE68915350D1 DE 68915350 D1 DE68915350 D1 DE 68915350D1 DE 68915350 T DE68915350 T DE 68915350T DE 68915350 T DE68915350 T DE 68915350T DE 68915350 D1 DE68915350 D1 DE 68915350D1
Authority
DE
Germany
Prior art keywords
enzymatic dissolution
enzymatic
dissolution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68915350T
Other languages
English (en)
Other versions
DE68915350T2 (de
Inventor
Jeffrey M Howell
Ramesh N Patel
Lazlo J Szarka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of DE68915350D1 publication Critical patent/DE68915350D1/de
Application granted granted Critical
Publication of DE68915350T2 publication Critical patent/DE68915350T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
DE1989615350 1988-07-14 1989-07-07 Verfahren zur enzymatischen Auflösung. Expired - Fee Related DE68915350T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21962488A 1988-07-14 1988-07-14

Publications (2)

Publication Number Publication Date
DE68915350D1 true DE68915350D1 (de) 1994-06-23
DE68915350T2 DE68915350T2 (de) 1994-08-25

Family

ID=22820042

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1989615350 Expired - Fee Related DE68915350T2 (de) 1988-07-14 1989-07-07 Verfahren zur enzymatischen Auflösung.

Country Status (6)

Country Link
EP (1) EP0350811B1 (de)
JP (1) JP2769194B2 (de)
CA (1) CA1318627C (de)
DE (1) DE68915350T2 (de)
ES (1) ES2052826T3 (de)
IE (1) IE64487B1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914331A (en) * 1990-02-01 1999-06-22 Emory University Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
US5728575A (en) 1990-02-01 1998-03-17 Emory University Method of resolution of 1,3-oxathiolane nucleoside enantiomers
EP0538693A3 (en) * 1991-10-23 1994-08-17 Squibb & Sons Inc Stereoselective preparation of halophenyl alcohols
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
US5420337A (en) * 1992-11-12 1995-05-30 E. R. Squibb & Sons, Inc. Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
ES2120881B1 (es) * 1996-02-05 1999-11-16 Dsm Deretil S A Enantiomeros de 5-metil-1, 3-tiazin-2, 4-diona y su empleo en la sintesis de intermedios de farmacos quirales.
AU4250501A (en) * 2000-04-06 2001-10-23 Societe Des Produits Nestle S.A. Preparation of thiols and derivatives by bio-conversion

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0130752B1 (de) * 1983-07-04 1991-02-27 Mitsubishi Rayon Co., Ltd. Verfahren zur Herstellung von optisch aktiven Carbonsäuren und von Antipodenestern
JPH06740B2 (ja) * 1984-08-16 1994-01-05 三菱レイヨン株式会社 光学活性カルボン酸アミドの製造法
WO1987005328A1 (en) * 1986-03-07 1987-09-11 Wisconsin Alumni Research Foundation Process for preparing optically-active 3-acylthio-2-methylpropionic acid derivatives
DE3740165A1 (de) * 1986-11-27 1988-06-09 Sumitomo Chemical Co Verfahren zur herstellung von hydroxycyclopentenonen

Also Published As

Publication number Publication date
JPH0260599A (ja) 1990-03-01
EP0350811A3 (de) 1991-04-10
DE68915350T2 (de) 1994-08-25
IE64487B1 (en) 1995-08-09
IE892110L (en) 1990-01-14
EP0350811B1 (de) 1994-05-18
EP0350811A2 (de) 1990-01-17
JP2769194B2 (ja) 1998-06-25
CA1318627C (en) 1993-06-01
ES2052826T3 (es) 1994-07-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee