DE68927669T2 - Verfahren zur herstellung von in lösungsmitteln verdünnbaren mikroträgern - Google Patents

Verfahren zur herstellung von in lösungsmitteln verdünnbaren mikroträgern

Info

Publication number
DE68927669T2
DE68927669T2 DE68927669T DE68927669T DE68927669T2 DE 68927669 T2 DE68927669 T2 DE 68927669T2 DE 68927669 T DE68927669 T DE 68927669T DE 68927669 T DE68927669 T DE 68927669T DE 68927669 T2 DE68927669 T2 DE 68927669T2
Authority
DE
Germany
Prior art keywords
sdmc
solvent
diluted
carriers
solvents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927669T
Other languages
English (en)
Other versions
DE68927669D1 (de
Inventor
Michael W Fountain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fountain Pharmaceuticals Inc
Original Assignee
Fountain Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fountain Pharmaceuticals Inc filed Critical Fountain Pharmaceuticals Inc
Application granted granted Critical
Publication of DE68927669D1 publication Critical patent/DE68927669D1/de
Publication of DE68927669T2 publication Critical patent/DE68927669T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/72—Encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Birds (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Materials For Medical Uses (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE68927669T 1988-06-08 1989-06-08 Verfahren zur herstellung von in lösungsmitteln verdünnbaren mikroträgern Expired - Fee Related DE68927669T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20421488A 1988-06-08 1988-06-08
PCT/US1989/002454 WO1989011850A1 (en) 1988-06-08 1989-06-08 Method for making solvent dilution microcarriers

Publications (2)

Publication Number Publication Date
DE68927669D1 DE68927669D1 (de) 1997-02-27
DE68927669T2 true DE68927669T2 (de) 1997-05-07

Family

ID=22757075

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927669T Expired - Fee Related DE68927669T2 (de) 1988-06-08 1989-06-08 Verfahren zur herstellung von in lösungsmitteln verdünnbaren mikroträgern

Country Status (13)

Country Link
EP (1) EP0372070B1 (de)
JP (1) JP2934889B2 (de)
KR (1) KR900701257A (de)
AT (1) ATE147622T1 (de)
AU (2) AU628355B2 (de)
CA (1) CA1340241C (de)
DE (1) DE68927669T2 (de)
ES (1) ES2013531A6 (de)
HK (1) HK1007498A1 (de)
IL (1) IL90561A (de)
NO (1) NO180771C (de)
SG (1) SG45461A1 (de)
WO (1) WO1989011850A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
DE4136553A1 (de) * 1991-11-06 1993-05-13 Biotechnolog Forschung Gmbh Impfstoff gegen schleimhauterreger und herstellungsverfahren
EP0621773B1 (de) * 1992-01-16 1998-11-25 The Board Of Regents, The University Of Texas System Formulierung und verwendung von carotenoiden in der krebsbehandlung
DE69424279T2 (de) * 1993-02-26 2000-12-21 Fountain Pharm Inc Abgabesystem für impfstoffe und lagerstabile vorstufenlösung zur nachträglichen verkapselung von aktivstoffen
EP0706374B1 (de) * 1993-06-30 1997-12-10 Genentech, Inc. Verfahren zur herstellung von liposomen
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
US5660854A (en) * 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
US5902604A (en) 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
IL160570A0 (en) 2001-09-26 2004-07-25 Baxter Int Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
JP5669058B2 (ja) * 2010-05-10 2015-02-12 独立行政法人科学技術振興機構 リポソームの製造方法
US9433580B2 (en) 2011-07-21 2016-09-06 Sun Pharmaceutical Industries Limited Topical pharmaceutical composition comprising nanonized silver sulfadiazine
US20130267490A1 (en) * 2010-08-02 2013-10-10 Ranbaxy Laboratories Limited Topical pharmaceutical composition comprising nanonized silver sulfadiazine and chlorhexidine gluconate
EP3283045B1 (de) 2015-04-13 2021-02-17 Fountain Technologies International, LLC Einstufiges verfahren zur herstellung von ultrakleinen lipidstrukturen

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
US4556554A (en) * 1981-06-01 1985-12-03 Germaine Monteil Cosmetiques Corp. Immobilized enzymes
DE3204124A1 (de) * 1982-02-06 1983-08-18 Bayer Ag, 5090 Leverkusen Antimykotische tampons mit hoher wirkstoff-freisetzung
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4599226A (en) * 1983-03-31 1986-07-08 Genetic Laboratories, Inc. Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
JPH0753661B2 (ja) * 1984-03-08 1995-06-07 フアレス フアーマスーチカル リサーチ エヌブイ プロ―リポソーム組成物及びリポソームの水性分散物を作る方法
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
FR2573308B1 (fr) * 1984-11-22 1987-01-09 Besins Iscovesco Laboratoires Procede de solubilisation, au moment de l'emploi, d'un principe actif lipophile dans une solution aqueuse, en vue de son administration par voie intraveineuse
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
US4752572A (en) * 1985-08-30 1988-06-21 Eastman Kodak Company Lipid vesicles containing labeled species and their analytical uses
ES2036593T3 (es) * 1986-06-12 1993-06-01 The Liposome Company, Inc. Composiciones que utilizan medicamentos antiinflamatorios no esteroidales encapsulados en liposomas.
US4839175A (en) * 1986-07-28 1989-06-13 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
EP0295248B2 (de) * 1986-12-23 1999-04-28 The Liposome Company, Inc. Liposomes präparat und antibiotikum

Also Published As

Publication number Publication date
JP2934889B2 (ja) 1999-08-16
IL90561A0 (en) 1990-01-18
IL90561A (en) 1993-08-18
NO180771B (no) 1997-03-10
NO180771C (no) 1997-06-18
EP0372070B1 (de) 1997-01-15
AU3777789A (en) 1990-01-05
ES2013531A6 (es) 1990-05-01
KR900701257A (ko) 1990-12-01
ATE147622T1 (de) 1997-02-15
SG45461A1 (en) 1998-01-16
HK1007498A1 (en) 1999-04-16
WO1989011850A1 (en) 1989-12-14
NO900591D0 (no) 1990-02-07
AU628355B2 (en) 1992-09-17
EP0372070A1 (de) 1990-06-13
NO900591L (no) 1990-02-07
DE68927669D1 (de) 1997-02-27
JPH02504642A (ja) 1990-12-27
EP0372070A4 (en) 1992-01-15
CA1340241C (en) 1998-12-15
AU2719492A (en) 1993-01-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee