DE68927348D1 - Künstlicher impfstoff gegen aids-virus - Google Patents

Künstlicher impfstoff gegen aids-virus

Info

Publication number
DE68927348D1
DE68927348D1 DE68927348T DE68927348T DE68927348D1 DE 68927348 D1 DE68927348 D1 DE 68927348D1 DE 68927348 T DE68927348 T DE 68927348T DE 68927348 T DE68927348 T DE 68927348T DE 68927348 D1 DE68927348 D1 DE 68927348D1
Authority
DE
Germany
Prior art keywords
vaccine against
aids virus
against aids
artificial
artificial vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927348T
Other languages
English (en)
Other versions
DE68927348T2 (de
Inventor
Jay Berzofsky
Paula Hale
Anne Hosmalin
Hanah Margalit
John Spouge
James Cornette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
US Department of Commerce
Original Assignee
US Department of Health and Human Services
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, US Department of Commerce filed Critical US Department of Health and Human Services
Publication of DE68927348D1 publication Critical patent/DE68927348D1/de
Application granted granted Critical
Publication of DE68927348T2 publication Critical patent/DE68927348T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/22—Viral peptide or viral protein
    • Y10S930/221—Retrovirus related, or human immunodeficiency virus related, or simian immunodeficiency virus related
DE68927348T 1988-07-21 1989-07-19 Künstlicher impfstoff gegen aids-virus Expired - Fee Related DE68927348T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/222,684 US5030449A (en) 1988-07-21 1988-07-21 Synthetic vaccine against AIDS virus
PCT/US1989/003123 WO1990000901A1 (en) 1988-07-21 1989-07-19 Synthetic vaccine against aids virus

Publications (2)

Publication Number Publication Date
DE68927348D1 true DE68927348D1 (de) 1996-11-21
DE68927348T2 DE68927348T2 (de) 1997-02-13

Family

ID=22833252

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927348T Expired - Fee Related DE68927348T2 (de) 1988-07-21 1989-07-19 Künstlicher impfstoff gegen aids-virus

Country Status (9)

Country Link
US (1) US5030449A (de)
EP (1) EP0429477B1 (de)
JP (1) JP2676166B2 (de)
AT (1) ATE144143T1 (de)
AU (1) AU624628B2 (de)
CA (1) CA1339240C (de)
DE (1) DE68927348T2 (de)
IL (1) IL91007A (de)
WO (1) WO1990000901A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939074A (en) * 1986-12-30 1999-08-17 The United States Of America As Represented By The Department Of Health And Human Services Multideterminant peptide antigens
US5128319A (en) * 1987-08-28 1992-07-07 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
US6210873B1 (en) 1987-08-28 2001-04-03 Board Of Regents, The University Of Texas System Methods and compositions for the priming of specific cytotoxic T-lymphocyte response
US5456924A (en) * 1988-12-23 1995-10-10 Immunotec Research Corporation Ltd. Method of treatment of HIV-seropositive individuals with dietary whey proteins
EP0362909A3 (de) * 1988-08-26 1990-11-14 Akzo N.V. Synthetische Polypeptide, immunochemisch aktiv mit HIV-Antikörpern
CA2035576A1 (en) * 1990-02-07 1991-08-08 Alexander R. Neurath Conformational epitopes of human immunodeficiency virus envelope glycoprotein gp120 hiv-1
JPH05506669A (ja) * 1990-09-25 1993-09-30 ペプテック　（ユーケイ）　リミテッド エイズ治療法及びワクチン
CA2106567A1 (en) * 1991-03-22 1992-09-23 William V. Williams Method of modulating mammalian t-cell response
US6419931B1 (en) * 1991-08-26 2002-07-16 Epimmune Inc. Compositions and methods for eliciting CTL immunity
WO1993004697A1 (en) * 1991-08-29 1993-03-18 The Government Of The United States Of America As Represented By The Department Of Health And Human Services Multideterminant peptide antigens that stimulate helper t lymphocyte response to hiv in a range of human subjects
EP0671947B1 (de) * 1991-12-02 2000-03-08 The Board Of Regents, The University Of Texas System Zusammensetzungen zum auslösen cytotoxischer t-lymphozyten gegen viren
WO1993019775A1 (en) * 1992-03-31 1993-10-14 Medimmune, Inc. Administration of liposomes containing peptides or proteins including ctl eptitopes of hiv proteins
EP0652895B1 (de) * 1992-07-20 1999-08-18 Duke University Zusammensetzungen die die hiv replikation inhibieren
DE4228787A1 (de) * 1992-08-29 1994-03-03 Chemotherapeutisches Forschungsinstitut Georg Speyer Haus Neue HIV-1-Virusisolate eines Subtyps, Vakzine gegen HIV-1-Virusinfektionen dieses Subtyps und Verfahren zu ihrer Herstellung, Verwendung der HIV-1-Virusisolate
JP3277045B2 (ja) * 1992-10-06 2002-04-22 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング Ｈｉｖ−グループのレトロウイルスおよびその使用
US5607914A (en) * 1993-01-13 1997-03-04 Pioneer Hi-Bred International, Inc. Synthetic antimicrobial peptides
US5869624A (en) * 1993-03-26 1999-02-09 Progenics Pharmaceuticals, Inc. HIV-1 vaccines, antibody compositions related thereto, and therapeutic and prophylactic uses thereof
US5603933A (en) * 1993-08-31 1997-02-18 Board Of Regents, The University Of Texas CD4 peptides for binding to viral envelope proteins
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
US6749856B1 (en) 1997-09-11 2004-06-15 The United States Of America, As Represented By The Department Of Health And Human Services Mucosal cytotoxic T lymphocyte responses
BR0108210A (pt) 2000-02-04 2002-10-22 Univ Duke Vacina contra o vìrus da imunodeficiência humana
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
CN101146550B (zh) * 2004-12-29 2013-04-17 曼康公司 免疫原性组合物用于制备引发和增强免疫应答的试剂盒的用途
CA2793959C (en) 2010-03-25 2019-06-04 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
US20140065601A1 (en) * 2011-03-23 2014-03-06 Tamar Jehuda-Cohen Method and kit for estimating human immunodeficiency virus (hiv) incidence
ES2667425T3 (es) 2011-06-10 2018-05-10 Oregon Health & Science University Glucoproteínas y vectores recombinantes de CMV
EP2568289A3 (de) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunselektion von rekombinantem vesikulärem Stomatitisvirus mit Expression von HIV-1-Proteinen durch Breitbandneutralisierungs-Antikörper
EP2586461A1 (de) 2011-10-27 2013-05-01 Christopher L. Parks Von einem eingehüllten Virus abgeleitete Virenpartikel
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
EP2873423B1 (de) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
WO2015195812A1 (en) 2014-06-17 2015-12-23 The Research Foundation For The State University Of New York Ship inhibition to induce activation of natural killer cells
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63501716A (ja) * 1985-10-24 1988-07-14 サウスウエスト・ファウンデ−ション・フォア・バイオメディカル・リサ−チ 合成ペプチドおよびａｉｄｓおよびａｒｃの診断ならびにワクチン注射へのその使用
DE3787002T2 (de) * 1986-12-30 1993-11-25 Us Health Synthetische Peptide, die zelluläre Immunität gegen den AIDS-Virus und dessen Proteine erzeugen.
EP0400076B1 (de) * 1988-01-26 1996-05-15 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Synthetisches antigen zum bewirken einer anti-hiv-reaktion
EP0330359A3 (de) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Zusammensetzung, verwendbar zur Diagnose und Behandlung von HIV-I-Infektion

Also Published As

Publication number Publication date
AU624628B2 (en) 1992-06-18
WO1990000901A1 (en) 1990-02-08
EP0429477A4 (en) 1991-11-13
DE68927348T2 (de) 1997-02-13
CA1339240C (en) 1997-08-05
ATE144143T1 (de) 1996-11-15
JP2676166B2 (ja) 1997-11-12
JPH03504384A (ja) 1991-09-26
EP0429477B1 (de) 1996-10-16
IL91007A (en) 1995-08-31
AU3967089A (en) 1990-02-19
IL91007A0 (en) 1990-02-09
EP0429477A1 (de) 1991-06-05
US5030449A (en) 1991-07-09

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8339 Ceased/non-payment of the annual fee