DE68921153D1 - Chemisches Verfahren zur Herstellung von Purinderivaten. - Google Patents

Chemisches Verfahren zur Herstellung von Purinderivaten.

Info

Publication number
DE68921153D1
DE68921153D1 DE68921153T DE68921153T DE68921153D1 DE 68921153 D1 DE68921153 D1 DE 68921153D1 DE 68921153 T DE68921153 T DE 68921153T DE 68921153 T DE68921153 T DE 68921153T DE 68921153 D1 DE68921153 D1 DE 68921153D1
Authority
DE
Germany
Prior art keywords
production
chemical process
purine derivatives
purine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68921153T
Other languages
English (en)
Other versions
DE68921153T2 (de
Inventor
Graham Richard Beecham Ph Geen
John Christopher Beecha Hanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis International Pharmaceutical Ltd
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE68921153D1 publication Critical patent/DE68921153D1/de
Publication of DE68921153T2 publication Critical patent/DE68921153T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE68921153T 1988-09-21 1989-09-18 Chemisches Verfahren zur Herstellung von Purinderivaten. Expired - Lifetime DE68921153T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888822236A GB8822236D0 (en) 1988-09-21 1988-09-21 Chemical process

Publications (2)

Publication Number Publication Date
DE68921153D1 true DE68921153D1 (de) 1995-03-23
DE68921153T2 DE68921153T2 (de) 1995-07-27

Family

ID=10644039

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68921153T Expired - Lifetime DE68921153T2 (de) 1988-09-21 1989-09-18 Chemisches Verfahren zur Herstellung von Purinderivaten.

Country Status (8)

Country Link
US (1) US5138057A (de)
EP (1) EP0369583B1 (de)
JP (1) JP3089354B2 (de)
DE (1) DE68921153T2 (de)
ES (1) ES2067549T3 (de)
GB (1) GB8822236D0 (de)
GR (1) GR3015327T3 (de)
PT (1) PT91749B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
GB9407698D0 (en) * 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
US5606100A (en) * 1994-12-21 1997-02-25 Lonza Ltd. Process for the preparation of trialkyl ester derivatives
GB9615275D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
ES2138535B1 (es) * 1996-07-20 2000-11-16 Smithkline Beecham Plc Procedimiento para la preparacion de los compuestos antivirales penciclovir y famciclovir.
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
CA2251481A1 (en) * 1997-11-12 1999-05-12 Junichi Yasuoka Purine derivatives having cyclopropane ring
AU7214198A (en) * 1998-04-02 1999-10-25 Lonza A.G. Carboxylic acid-2-acyloxymethyl-4-aminobutyl esters and method for producing same
KR100573859B1 (ko) * 2002-07-15 2006-04-25 경동제약 주식회사 9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의제조방법
WO2004018470A2 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
TW200510415A (en) * 2003-04-30 2005-03-16 Teva Pharma Process for the preparation of famciclovir
KR100573860B1 (ko) * 2003-06-13 2006-04-25 경동제약 주식회사 2-아미노-9-(2-치환에틸)푸린을 이용한 9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의 제조방법
WO2005026167A1 (en) * 2003-09-04 2005-03-24 Teva Pharmaceutical Industries Ltd. Process for preparing famciclovir
JP2007538087A (ja) * 2004-05-18 2007-12-27 テバ ファーマシューティカル インダストリーズ リミティド 結晶固形ファムシクロビルを調製するための乾燥方法
JP4887500B2 (ja) * 2004-09-16 2012-02-29 国立大学法人岐阜大学 ヌクレオシド類似体またはその塩
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
WO2008155613A1 (en) * 2007-06-21 2008-12-24 Aurobindo Pharma Ltd An improved process for preparing purine derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347187A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein
US4347185A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0182024B1 (de) * 1984-09-20 1991-04-03 Beecham Group Plc Purin-Derivate und ihre pharmazeutische Verwendung
GB8507606D0 (en) * 1985-03-23 1985-05-01 Beecham Group Plc Process
EP0302644B1 (de) * 1987-08-01 1997-01-29 Beecham Group Plc Purinverbindungen und ihre Herstellung
GB8817270D0 (en) * 1988-07-20 1988-08-24 Beecham Group Plc Novel process
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process

Also Published As

Publication number Publication date
GB8822236D0 (en) 1988-10-26
DE68921153T2 (de) 1995-07-27
PT91749B (pt) 1995-05-31
EP0369583A1 (de) 1990-05-23
GR3015327T3 (en) 1995-06-30
US5138057A (en) 1992-08-11
PT91749A (pt) 1990-03-30
EP0369583B1 (de) 1995-02-15
JPH02121992A (ja) 1990-05-09
ES2067549T3 (es) 1995-04-01
JP3089354B2 (ja) 2000-09-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD., HAMILT