DE68916504D1 - Azetidinone als Zwischenprodukte für Carbacephalosporine und Verfahren. - Google Patents

Azetidinone als Zwischenprodukte für Carbacephalosporine und Verfahren.

Info

Publication number
DE68916504D1
DE68916504D1 DE68916504T DE68916504T DE68916504D1 DE 68916504 D1 DE68916504 D1 DE 68916504D1 DE 68916504 T DE68916504 T DE 68916504T DE 68916504 T DE68916504 T DE 68916504T DE 68916504 D1 DE68916504 D1 DE 68916504D1
Authority
DE
Germany
Prior art keywords
intermediates
beta
acid esters
carbacephalosporins
azetidinones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68916504T
Other languages
English (en)
Other versions
DE68916504T2 (de
Inventor
John Paul Gardner
Billy Grinnell Jackson
James Aikins
Eddie V Tao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE68916504D1 publication Critical patent/DE68916504D1/de
Publication of DE68916504T2 publication Critical patent/DE68916504T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE68916504T 1988-10-11 1989-10-09 Azetidinone als Zwischenprodukte für Carbacephalosporine und Verfahren. Expired - Fee Related DE68916504T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25653888A 1988-10-11 1988-10-11

Publications (2)

Publication Number Publication Date
DE68916504D1 true DE68916504D1 (de) 1994-08-04
DE68916504T2 DE68916504T2 (de) 1994-11-24

Family

ID=22972608

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68916504T Expired - Fee Related DE68916504T2 (de) 1988-10-11 1989-10-09 Azetidinone als Zwischenprodukte für Carbacephalosporine und Verfahren.

Country Status (7)

Country Link
EP (1) EP0365190B1 (de)
JP (1) JP3001910B2 (de)
KR (1) KR0169096B1 (de)
AT (1) ATE107928T1 (de)
DE (1) DE68916504T2 (de)
ES (1) ES2055087T3 (de)
IL (1) IL91932A0 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453503A (en) * 1988-10-11 1995-09-26 Eli Lilly And Company Azetidinone intermediates to carbacephalosporins and process
US5521307A (en) * 1992-02-18 1996-05-28 Eli Lilly And Company Methods and compounds for the preparation of carbacephems
FR2977830B1 (fr) 2011-07-12 2013-07-12 Michelin Soc Tech Bande de roulement de pneu pourvue d'incisions comprenant des parties larges et des parties etroites

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics

Also Published As

Publication number Publication date
ATE107928T1 (de) 1994-07-15
IL91932A0 (en) 1990-06-10
JP3001910B2 (ja) 2000-01-24
ES2055087T3 (es) 1994-08-16
KR0169096B1 (ko) 1999-01-15
DE68916504T2 (de) 1994-11-24
EP0365190B1 (de) 1994-06-29
JPH02157278A (ja) 1990-06-18
KR900006329A (ko) 1990-05-07
EP0365190A1 (de) 1990-04-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee