DE68907220D1 - Verfahren zur manipulation des zelltyps von eukaryonten. - Google Patents

Verfahren zur manipulation des zelltyps von eukaryonten.

Info

Publication number
DE68907220D1
DE68907220D1 DE8989905491T DE68907220T DE68907220D1 DE 68907220 D1 DE68907220 D1 DE 68907220D1 DE 8989905491 T DE8989905491 T DE 8989905491T DE 68907220 T DE68907220 T DE 68907220T DE 68907220 D1 DE68907220 D1 DE 68907220D1
Authority
DE
Germany
Prior art keywords
gene
cell
eukaryonts
manipulating
cell type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989905491T
Other languages
English (en)
Other versions
DE68907220T2 (de
Inventor
Ronald Mckay
Parmjit Jat
Guillermina Lamazan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of DE68907220D1 publication Critical patent/DE68907220D1/de
Publication of DE68907220T2 publication Critical patent/DE68907220T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Image Processing (AREA)
DE89905491T 1988-04-12 1989-04-12 Verfahren zur manipulation des zelltyps von eukaryonten. Expired - Fee Related DE68907220T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18054888A 1988-04-12 1988-04-12
US20176288A 1988-06-02 1988-06-02

Publications (2)

Publication Number Publication Date
DE68907220D1 true DE68907220D1 (de) 1993-07-22
DE68907220T2 DE68907220T2 (de) 1994-01-27

Family

ID=26876422

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89905491T Expired - Fee Related DE68907220T2 (de) 1988-04-12 1989-04-12 Verfahren zur manipulation des zelltyps von eukaryonten.

Country Status (5)

Country Link
EP (1) EP0428519B1 (de)
JP (1) JPH03504799A (de)
AT (1) ATE90724T1 (de)
DE (1) DE68907220T2 (de)
WO (1) WO1989009816A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4669189A (en) * 1988-11-23 1990-06-12 Baylor College Of Medicine Neural cell transplantation
FR2649721B1 (fr) * 1989-07-13 1994-07-08 Univ Paris Construction immortalisante pour l'immortalisation cellulaire conditionnelle
GB8928884D0 (en) * 1989-12-21 1990-02-28 Feldmann Marc Transformed cell lines
GB9003791D0 (en) * 1990-02-20 1990-04-18 Ludwig Inst Cancer Res Transgenic animals,cell lines therefrom,and their use
FR2670215B1 (fr) * 1990-12-10 2000-10-13 Lignees de cellules immortalisees et leurs applications, notamment a la production de cellules differenciees.
US5866759A (en) * 1991-02-20 1999-02-02 Ludwig Institute For Cancer Research Transgenic mice expressing TSSV40 large T antigen
US5489743A (en) * 1993-01-19 1996-02-06 Amgen Inc. Transgenic animal models for thrombocytopenia
US5753491A (en) * 1993-04-13 1998-05-19 Us Health Use of neuro-derived fetal cell lines for transplantation therapy
EP0696205B1 (de) * 1993-04-13 2002-01-23 GOVERNMENT OF THE UNITED STATES OF AMERICA, as repr. by THE SECR. OF THE DEPT. OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS Verwendung von neuronalen fötalen zellinien für transplantationstherapie
US5514552A (en) * 1993-04-30 1996-05-07 Arch Development Corporation Hybrid neuronal cell lines compositions and methods
US5681701A (en) * 1993-07-12 1997-10-28 Mayo Foundation For Medical Education And Research Immortalized human fetal osteoblastic cells
US5833979A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Methods and compositions of growth control for cells encapsulated within bioartificial organs
US5935849A (en) * 1994-07-20 1999-08-10 Cytotherapeutics, Inc. Methods and compositions of growth control for cells encapsulated within bioartificial organs
GB9422643D0 (en) * 1994-11-08 1995-01-04 Stringer Bradley M J Neural cell lines
US6495364B2 (en) 1995-05-23 2002-12-17 Neurotech, S.A. Mx-1 conditionally immortalized cells
GB9518606D0 (en) 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
GB9607953D0 (en) * 1996-04-17 1996-06-19 Univ Liverpool Transgenic rat
US6713247B1 (en) 1996-09-03 2004-03-30 Signal Pharmaceuticials, Inc. Human CNS cell lines and methods of use therefor
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
DE19816116C2 (de) * 1998-04-09 2000-06-29 Gsf Forschungszentrum Umwelt Verfahren zur Immortalisation von Zellen mit Hilfe konditional transformierter Helferzellen
GB9907243D0 (en) 1999-03-29 1999-05-26 Reneuron Ltd Therapy
GB0005856D0 (en) * 2000-03-10 2000-05-03 Reneuron Ltd Genetic constructs
DE602005002430T2 (de) 2004-09-30 2008-06-19 Reneuron Ltd., Guildford Zelllinie

Also Published As

Publication number Publication date
EP0428519B1 (de) 1993-06-16
DE68907220T2 (de) 1994-01-27
WO1989009816A1 (en) 1989-10-19
ATE90724T1 (de) 1993-07-15
JPH03504799A (ja) 1991-10-24
EP0428519A1 (de) 1991-05-29

Similar Documents

Publication Publication Date Title
DE68907220D1 (de) Verfahren zur manipulation des zelltyps von eukaryonten.
DK15182A (da) Fremgangsmaade til fremstilling af recombinant-dna
DE69011906D1 (de) Verfahren und System zur Aktualisierung des Steuerparameterwertes, der den Punkt des beginnenden Eingriffs der Hauptkupplung anzeigt.
NO951191D0 (no) Oligonukleotider med en konservert G4-kjernesekvens
ATE191513T1 (de) Verfahren zur amplifikation von nukleinsäuren
DE3856362D1 (de) Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen
DK605987A (da) Bestemte dna-sekvenser afledt af et papillomavirus-genom, deres anvendelse til in vitro diagnoseformaal og fremstilling af antigeniske praeparater bestemte dna-sekvenser afledt af et papillomavirus-genom, deres anvendelse til in vitro diagnoseformaal og fremstilling af antigeniske praeparater
ATE318913T1 (de) System zum exprimieren einer hyperthermostabilen protease
DK1015575T3 (da) Shuffling af heterologe DNA-sekvenser
ATE320500T1 (de) Nukleotid-sequenzen zur kontrolle der exprimierung von dns-sequenzen in einem zellulärem wirt
HUP0500699A2 (hu) Zzírszövetből származó stromasejtek endokrin hasnyálmirigy differenciálódása és annak alkalmazása
ATE310812T1 (de) Derivate von zinkfingerproteinen und methoden
ATE330007T1 (de) Verfahren zur erhöhung der expression von endogenen oder exogenen genprodukten in pflanzen
HUP0001660A2 (hu) Megváltoztatott növekedésű növények
DE3888360D1 (de) Hochspannungsschalter und verfahren zur ansteuerung von verbrauchern mittels des hochspannungsschalters.
DK1200561T3 (da) Rekombinant stabil celleklon, dens fremstilling og anvendelse
DE69231567T2 (de) Screeningverfahren von morphogenischen Proteinen
DE3889524D1 (de) Methode zur Stabilisierung von eingesättigten Organosilicium-Zusammensetzungen.
DK0562508T3 (da) Nyt knogle-relateret protein OSF-2, fremgangsmåde til dets fremstilling samt farmaceutisk præparat med indhold deraf
DE60032001D1 (de) Verfahren zur stabilisierung von thrombin
DE69009719D1 (de) Verfahren zur Züchtung von Antimon-dotierten Silizium-Einkristallen.
DE69031694D1 (de) Glutamin zur Behandlung von beeinträchtigten Abwehrkräften
DE69125066D1 (de) cDNS-Sequenz und Detektion des Hepatitis C-Virus
DE3885395D1 (de) Expressionsvektor und Verfahren zur Expression von heterologen Proteinen in Säugerzellen.
ATE31733T1 (de) Verfahren zur herstellung von hybridisierungssonden.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee