DE68905552T2 - Immunostimulierende peptide, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Immunostimulierende peptide, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
DE68905552T2
DE68905552T2 DE8989113447T DE68905552T DE68905552T2 DE 68905552 T2 DE68905552 T2 DE 68905552T2 DE 8989113447 T DE8989113447 T DE 8989113447T DE 68905552 T DE68905552 T DE 68905552T DE 68905552 T2 DE68905552 T2 DE 68905552T2
Authority
DE
Germany
Prior art keywords
arg
ala
formula
peptides
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989113447T
Other languages
English (en)
Other versions
DE68905552D1 (de
Inventor
Brunetto Brunetti
Marco Prada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ellem Industria Farmaceutica SpA
Original Assignee
Ellem Industria Farmaceutica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ellem Industria Farmaceutica SpA filed Critical Ellem Industria Farmaceutica SpA
Application granted granted Critical
Publication of DE68905552D1 publication Critical patent/DE68905552D1/de
Publication of DE68905552T2 publication Critical patent/DE68905552T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/66Thymopoietins
    • C07K14/662Thymopoietins at least 1 amino acid in D-form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE8989113447T 1988-07-29 1989-07-21 Immunostimulierende peptide, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen. Expired - Fee Related DE68905552T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821556A IT1226552B (it) 1988-07-29 1988-07-29 Peptidi immunostimolanti.

Publications (2)

Publication Number Publication Date
DE68905552D1 DE68905552D1 (de) 1993-04-29
DE68905552T2 true DE68905552T2 (de) 1993-07-15

Family

ID=11183555

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8989113447T Expired - Fee Related DE68905552T2 (de) 1988-07-29 1989-07-21 Immunostimulierende peptide, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DE198989113447T Pending DE353565T1 (de) 1988-07-29 1989-07-21 Immunostimulierende peptide, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE198989113447T Pending DE353565T1 (de) 1988-07-29 1989-07-21 Immunostimulierende peptide, deren verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (9)

Country Link
US (1) US5079231A (de)
EP (1) EP0353565B1 (de)
JP (1) JPH0288595A (de)
AT (1) ATE87315T1 (de)
DE (2) DE68905552T2 (de)
ES (1) ES2013584A4 (de)
GR (1) GR900300062T1 (de)
HU (1) HU204071B (de)
IT (1) IT1226552B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992009628A1 (en) * 1990-11-23 1992-06-11 Immunodynamics, Inc. Synthetic immunoactive peptides having immunomodulating and therapeutic activities
US5492894A (en) * 1991-03-21 1996-02-20 The Procter & Gamble Company Compositions for treating wrinkles comprising a peptide
BR9306984A (pt) 1992-08-27 1999-01-12 Deakin Res Ltd Análogo de antígeno de peptídeo de um antígeno de peptídeo nativo vacina anticorpo processo para vacinar um hospedeiro necessitando deste tratamento estojo diagnóstico processos para preparar um análogo de um antiígeno de um antígeno de peptídeo nativo para preparar uma vacina para analisar uma amostra para um antígeno de peptídeo nativo e para analisar uma amostra para um anticorpo
US6080719A (en) * 1996-02-23 2000-06-27 Hoechst Aktiengesellschaft Cyclohexapeptides and their mixtures, a process for preparing them, and their use
AU8912698A (en) 1997-08-19 1999-03-08 University Of Medicine And Dentistry Of New Jersey Inhibition of hiv-1 replication using d-amino acid peptides
FR2806727A1 (fr) * 2000-03-23 2001-09-28 Pf Medicament Molecule d'interet pharmaceutique comprotant en son extremite n-terminale un acide glutamique ou une glutamine sous forme de sel d'addition d'acide fort physiologiquement acceptable
JP2006508049A (ja) * 2002-08-13 2006-03-09 ワイエス 増殖因子βタンパク質を形質転換するための可溶化賦形剤としてのペプチド
US20100260680A1 (en) * 2007-06-05 2010-10-14 Oriental Yeast Co., Ltd. Novel bone mass increasing agent
CN103554221B (zh) * 2010-04-29 2015-09-02 上海医药工业研究院 一组蛇毒来源的活性肽的制备方法
KR101791526B1 (ko) * 2016-02-18 2017-11-01 (주)케어젠 발모 촉진 활성을 나타내는 펩타이드 및 이의 용도
EP3794015A4 (de) * 2018-05-15 2022-03-30 InterK Peptide Therapeutics Limited Aktivierungsmittel
KR20210021984A (ko) * 2018-05-15 2021-03-02 인터크 펩타이드 테라퓨틱스 리미티드 펩타이드 활성화 제제

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH551948A (de) * 1969-04-05 1974-07-31 Hoechst Ag Verfahren zur herstellung von peptiden.
CH665645A5 (fr) * 1981-07-09 1988-05-31 Michel Flork Derives de dipeptides et leur procede de preparation.
US4581168A (en) * 1983-02-21 1986-04-08 Sanofi Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides
DE3401545A1 (de) * 1983-08-03 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue peptide mit immunstimulierender wirkung, verfahren zu deren herstellung und deren verwendung
US4505853A (en) * 1983-11-18 1985-03-19 Ortho Pharmaceutical Corporation Enzyme-resistant immunomodulatory peptides
FR2567524B1 (fr) * 1984-07-10 1987-11-27 Sanofi Sa Procede de synthese de la somatocrinine en phase liquide et peptides intermediaires
US4654419A (en) * 1984-08-08 1987-03-31 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen
WO1987002775A1 (en) * 1985-10-24 1987-05-07 Southwest Foundation For Biomedical Research Synthetic peptides and use for diagnosis and vaccination for aids and arc
IT1188645B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
IT1222437B (it) * 1987-08-04 1990-09-05 Ellem Ind Farmaceutica Tripeptidi utili come immunostimolanti e nella prevenzione delle metastasi e relativo procedimento di preparazione

Also Published As

Publication number Publication date
EP0353565A1 (de) 1990-02-07
DE353565T1 (de) 1990-06-13
HU204071B (en) 1991-11-28
GR900300062T1 (en) 1991-07-31
US5079231A (en) 1992-01-07
HUT53914A (en) 1990-12-28
ES2013584A4 (es) 1990-05-16
DE68905552D1 (de) 1993-04-29
IT8821556A0 (it) 1988-07-29
JPH0288595A (ja) 1990-03-28
IT1226552B (it) 1991-01-24
EP0353565B1 (de) 1993-03-24
ATE87315T1 (de) 1993-04-15

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee