DE60336546D1 - Testagentien zur beurteilung der pharmakologischen wirkung eines arzneistoffs sowie verfahren und reagentien zum screening eines arzneistoffs mit ausgezeichneter verabreichungswirkung und/oder geringer nebenwirkung aus enzyme, enzyminhibitoren oder rezeptorliganden umfassenden arzneistoffen und/oder prodrugs davon - Google Patents
Testagentien zur beurteilung der pharmakologischen wirkung eines arzneistoffs sowie verfahren und reagentien zum screening eines arzneistoffs mit ausgezeichneter verabreichungswirkung und/oder geringer nebenwirkung aus enzyme, enzyminhibitoren oder rezeptorliganden umfassenden arzneistoffen und/oder prodrugs davonInfo
- Publication number
- DE60336546D1 DE60336546D1 DE60336546T DE60336546T DE60336546D1 DE 60336546 D1 DE60336546 D1 DE 60336546D1 DE 60336546 T DE60336546 T DE 60336546T DE 60336546 T DE60336546 T DE 60336546T DE 60336546 D1 DE60336546 D1 DE 60336546D1
- Authority
- DE
- Germany
- Prior art keywords
- enzyme
- medicament
- pharmaceutical agent
- medicine
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
- A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1206—Administration of radioactive gases, aerosols or breath tests
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/40—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Dispersion Chemistry (AREA)
- Atmospheric Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002044526 | 2002-02-21 | ||
JP2002044791 | 2002-02-21 | ||
PCT/JP2003/001868 WO2003071271A1 (fr) | 2002-02-21 | 2003-02-20 | Agents de tests pour evaluer l'effet pharmacologique de medicaments, et procede et reactifs pour selectionner des medicaments ayant un excellent effet d'administration et/ou peu d'effets secondaires parmi des medicaments avec enzymes, inhibiteurs d'enzymes ou ligands de recepteurs et/ou promedicaments de ceux-ci |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60336546D1 true DE60336546D1 (de) | 2011-05-12 |
Family
ID=27759664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60336546T Expired - Lifetime DE60336546D1 (de) | 2002-02-21 | 2003-02-20 | Testagentien zur beurteilung der pharmakologischen wirkung eines arzneistoffs sowie verfahren und reagentien zum screening eines arzneistoffs mit ausgezeichneter verabreichungswirkung und/oder geringer nebenwirkung aus enzyme, enzyminhibitoren oder rezeptorliganden umfassenden arzneistoffen und/oder prodrugs davon |
Country Status (12)
Country | Link |
---|---|
US (1) | US7404945B2 (de) |
EP (1) | EP1486785B1 (de) |
JP (1) | JPWO2003071271A1 (de) |
AT (1) | ATE503998T1 (de) |
AU (1) | AU2003211602B2 (de) |
CA (1) | CA2474993A1 (de) |
DE (1) | DE60336546D1 (de) |
MX (1) | MXPA04008180A (de) |
NO (1) | NO20043756L (de) |
NZ (1) | NZ534462A (de) |
PT (1) | PT1486785E (de) |
WO (1) | WO2003071271A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3640342A1 (de) | 2004-05-13 | 2020-04-22 | Nanobiosym, Inc. | Nano-pcr: verfahren und vorrichtung zur amplifikation und detektion von nukleinsäuren |
ES2450690T3 (es) | 2005-06-30 | 2014-03-25 | Otsuka America Pharmaceutical, Inc. | Método para individualizar la terapia con levodopa/carbidopa utilizando una prueba respiratoria |
JP2009534033A (ja) | 2006-04-21 | 2009-09-24 | ナノバイオシン,インコーポレイテッド | 薬物発見のための単一分子プラットホーム:抗癌剤および抗ウイルス剤の発見を含む薬物発見のための方法および装置 |
US10717965B2 (en) | 2013-01-10 | 2020-07-21 | Gloriana Therapeutics, Inc. | Mammalian cell culture-produced neublastin antibodies |
US10933417B2 (en) | 2013-03-15 | 2021-03-02 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
EP3083933A1 (de) | 2013-12-20 | 2016-10-26 | Biogen MA Inc. | Verwendung von perfusionssaatkulturen zur verbesserung der biopharmazeutischen fed-batch-produktionskapazitäten und der produktqualität |
WO2020086408A1 (en) | 2018-10-26 | 2020-04-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A high-yield perfusion-based transient gene expression bioprocess |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5625125A (en) | 1994-08-09 | 1997-04-29 | Dnx Biotherapeutics | Phospholipase A2 expressing transgenic animals |
JPH1180034A (ja) * | 1997-09-12 | 1999-03-23 | Tokyo Gas Co Ltd | フェニルアラニン水酸化酵素活性検査剤 |
JP3340699B2 (ja) * | 1998-06-05 | 2002-11-05 | 東京瓦斯株式会社 | 膵外分泌機能診断剤 |
US6284219B1 (en) * | 1998-06-30 | 2001-09-04 | Phenome Sciences Inc. | In vivo determination of metabolic function for use in therapy management |
GB9826899D0 (en) | 1998-12-08 | 1999-01-27 | Knoll Ag | Methods to treat depression and other psychiatric disorders and assays for compounds |
WO2000053800A1 (en) | 1999-03-09 | 2000-09-14 | Flohe Leopold | METHOD TO SEARCH FOR MALE ANTIFERTILITY DRUGS BASED ON PHGPx ACTIVITY DETERMINATION |
AU2001261394A1 (en) * | 2000-05-18 | 2001-11-26 | Metabolic Solutions, Inc. | Reverse isotope dilution assay and lactose intolerance assay |
-
2003
- 2003-02-20 EP EP03705358A patent/EP1486785B1/de not_active Expired - Lifetime
- 2003-02-20 AT AT03705358T patent/ATE503998T1/de not_active IP Right Cessation
- 2003-02-20 PT PT03705358T patent/PT1486785E/pt unknown
- 2003-02-20 MX MXPA04008180A patent/MXPA04008180A/es active IP Right Grant
- 2003-02-20 WO PCT/JP2003/001868 patent/WO2003071271A1/ja active Application Filing
- 2003-02-20 JP JP2003570123A patent/JPWO2003071271A1/ja active Pending
- 2003-02-20 US US10/503,557 patent/US7404945B2/en not_active Expired - Fee Related
- 2003-02-20 NZ NZ534462A patent/NZ534462A/en not_active IP Right Cessation
- 2003-02-20 AU AU2003211602A patent/AU2003211602B2/en not_active Ceased
- 2003-02-20 CA CA002474993A patent/CA2474993A1/en not_active Abandoned
- 2003-02-20 DE DE60336546T patent/DE60336546D1/de not_active Expired - Lifetime
-
2004
- 2004-09-08 NO NO20043756A patent/NO20043756L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MXPA04008180A (es) | 2005-05-16 |
AU2003211602A1 (en) | 2003-09-09 |
NO20043756L (no) | 2004-09-08 |
US7404945B2 (en) | 2008-07-29 |
PT1486785E (pt) | 2011-05-12 |
EP1486785A4 (de) | 2008-03-05 |
US20050079564A1 (en) | 2005-04-14 |
JPWO2003071271A1 (ja) | 2005-06-16 |
EP1486785B1 (de) | 2011-03-30 |
AU2003211602B2 (en) | 2008-05-22 |
EP1486785A1 (de) | 2004-12-15 |
NZ534462A (en) | 2007-06-29 |
ATE503998T1 (de) | 2011-04-15 |
CA2474993A1 (en) | 2003-08-28 |
WO2003071271A1 (fr) | 2003-08-28 |
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