DE60334144D1 - Verfahren und proben zur detektion des tumor spezifische fusion proteinen - Google Patents
Verfahren und proben zur detektion des tumor spezifische fusion proteinenInfo
- Publication number
- DE60334144D1 DE60334144D1 DE60334144T DE60334144T DE60334144D1 DE 60334144 D1 DE60334144 D1 DE 60334144D1 DE 60334144 T DE60334144 T DE 60334144T DE 60334144 T DE60334144 T DE 60334144T DE 60334144 D1 DE60334144 D1 DE 60334144D1
- Authority
- DE
- Germany
- Prior art keywords
- fusion proteins
- detecting
- samples
- tumor specific
- specific fusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y20/00—Nanooptics, e.g. quantum optics or photonic crystals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Mathematical Physics (AREA)
- Optics & Photonics (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02079666 | 2002-11-07 | ||
PCT/NL2003/000776 WO2004042398A1 (en) | 2002-11-07 | 2003-11-06 | Method and probes for the detection of a tunor specific fusion protein |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60334144D1 true DE60334144D1 (de) | 2010-10-21 |
Family
ID=32309413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60334144T Expired - Lifetime DE60334144D1 (de) | 2002-11-07 | 2003-11-06 | Verfahren und proben zur detektion des tumor spezifische fusion proteinen |
Country Status (13)
Country | Link |
---|---|
US (2) | US7575874B2 (de) |
EP (1) | EP1565746B1 (de) |
JP (1) | JP4594733B2 (de) |
CN (1) | CN1735805A (de) |
AT (1) | ATE480774T1 (de) |
AU (1) | AU2003279618B2 (de) |
CA (1) | CA2505509C (de) |
DE (1) | DE60334144D1 (de) |
DK (1) | DK1565746T3 (de) |
ES (1) | ES2352050T3 (de) |
NZ (1) | NZ540218A (de) |
PT (1) | PT1565746E (de) |
WO (1) | WO2004042398A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1565746E (pt) | 2002-11-07 | 2010-12-07 | Univ Erasmus | Método e sondas para a detecção de uma proteína de fusão específica a um tumor |
JP2007040834A (ja) * | 2005-08-03 | 2007-02-15 | Japan Science & Technology Agency | 免疫測定用試薬 |
US8124351B2 (en) | 2005-11-18 | 2012-02-28 | Board Of Regents, The University Of Texas System | Quantification of fusion proteins and their activity from chromosomal translocation |
US8134743B2 (en) * | 2007-07-18 | 2012-03-13 | Xerox Corporation | Methods and systems for routing and processing jobs in a production environment |
WO2009021026A1 (en) * | 2007-08-06 | 2009-02-12 | University Of Kentucky Research Foundation | Semi-synthetic antibodies as recognition elements |
BRPI0819739A2 (pt) * | 2007-11-21 | 2017-05-09 | Univ Erasmus Med Ct Rotterdam | sondas de fret otimizadas e usos das mesmas |
WO2012057689A1 (en) * | 2010-10-29 | 2012-05-03 | Ge Healthcare Bio-Sciences Ab | Proximity ligation technology for western blot applications |
US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
CN104155452A (zh) * | 2013-05-15 | 2014-11-19 | 复旦大学 | 一种检测细胞内蛋白质降解的方法 |
CN107209101B (zh) * | 2014-10-30 | 2019-10-25 | 鹿特丹伊拉斯谟大学医疗中心 | 用于诊断原发性免疫缺陷的试剂、方法和试剂盒 |
US20160146799A1 (en) * | 2014-11-05 | 2016-05-26 | Nirmidas Biotech, Inc. | Metal composites for enhanced imaging |
CN106124500B (zh) * | 2016-08-29 | 2019-09-03 | 华北理工大学 | 一种用菁染料可视化识别转铁蛋白的方法 |
CN110407918B (zh) * | 2019-07-22 | 2021-06-18 | 上海交通大学医学院附属瑞金医院 | 一种温敏靶向荧光探针及其制备方法和应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5091206A (en) * | 1987-10-26 | 1992-02-25 | Baxter Diagnostics Inc. | Process for producing magnetically responsive polymer particles and application thereof |
WO1992021032A1 (en) * | 1991-05-24 | 1992-11-26 | The Regents Of The University Of California | Methods for the detection of bcr-abl and abnormal abl proteins in leukemia patients |
US5514340A (en) * | 1994-01-24 | 1996-05-07 | Magnetix Biotechnology, Inc. | Device for separating magnetically labelled cells |
US6107457A (en) * | 1995-02-16 | 2000-08-22 | Board Of Regents, The University Of Texas System | Bcr-Abl directed compositions and uses for inhibiting Philadelphia chromosome stimulated cell growth |
US6159748A (en) * | 1995-03-13 | 2000-12-12 | Affinitech, Ltd | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry |
CA2290656C (en) | 1997-05-20 | 2008-01-15 | Erasmus Universiteit Rotterdam | Recognition of tumour-specific gene products in cancer |
US6686165B2 (en) | 1997-05-20 | 2004-02-03 | Erasmus Universiteit Rotterdam | Recognition of tumor-specific gene products in cancer |
JP3513068B2 (ja) * | 1999-05-12 | 2004-03-31 | 浜松ホトニクス株式会社 | 生細胞の細胞質内標的核酸を検出する方法 |
JP2004512012A (ja) * | 2000-04-04 | 2004-04-22 | メディカル リサーチ カウンシル | 細胞検出法 |
US7595202B2 (en) * | 2001-04-23 | 2009-09-29 | Teruyuki Nagamune | Analysis method using reporter (label) intermolecular interaction |
CA2411392C (en) * | 2001-11-07 | 2012-10-16 | Stemcell Technologies Inc. | Tetrameric antibody complexes for blocking non-specific binding of antigens |
PT1565746E (pt) | 2002-11-07 | 2010-12-07 | Univ Erasmus | Método e sondas para a detecção de uma proteína de fusão específica a um tumor |
EP1507147A1 (de) | 2003-08-12 | 2005-02-16 | Erasmus University Medical Center Rotterdam | Verfahren zum Nachweiss von niedrigem Gehalt an Fusionsprotein |
-
2003
- 2003-11-06 PT PT03772958T patent/PT1565746E/pt unknown
- 2003-11-06 CN CNA2003801083641A patent/CN1735805A/zh active Pending
- 2003-11-06 CA CA2505509A patent/CA2505509C/en not_active Expired - Fee Related
- 2003-11-06 DE DE60334144T patent/DE60334144D1/de not_active Expired - Lifetime
- 2003-11-06 ES ES03772958T patent/ES2352050T3/es not_active Expired - Lifetime
- 2003-11-06 AU AU2003279618A patent/AU2003279618B2/en not_active Ceased
- 2003-11-06 EP EP03772958A patent/EP1565746B1/de not_active Expired - Lifetime
- 2003-11-06 WO PCT/NL2003/000776 patent/WO2004042398A1/en active Application Filing
- 2003-11-06 NZ NZ540218A patent/NZ540218A/en unknown
- 2003-11-06 JP JP2004549717A patent/JP4594733B2/ja not_active Expired - Fee Related
- 2003-11-06 DK DK03772958.9T patent/DK1565746T3/da active
- 2003-11-06 AT AT03772958T patent/ATE480774T1/de active
-
2005
- 2005-05-05 US US11/122,775 patent/US7575874B2/en active Active
-
2009
- 2009-08-06 US US12/462,637 patent/US7993850B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20090305305A1 (en) | 2009-12-10 |
US7993850B2 (en) | 2011-08-09 |
WO2004042398A1 (en) | 2004-05-21 |
AU2003279618A1 (en) | 2004-06-07 |
US20050260684A1 (en) | 2005-11-24 |
US7575874B2 (en) | 2009-08-18 |
DK1565746T3 (da) | 2011-01-10 |
JP2006505774A (ja) | 2006-02-16 |
EP1565746A1 (de) | 2005-08-24 |
NZ540218A (en) | 2009-03-31 |
ATE480774T1 (de) | 2010-09-15 |
JP4594733B2 (ja) | 2010-12-08 |
AU2003279618B2 (en) | 2009-07-16 |
ES2352050T3 (es) | 2011-03-18 |
CA2505509A1 (en) | 2004-05-21 |
EP1565746B1 (de) | 2010-09-08 |
PT1565746E (pt) | 2010-12-07 |
ES2352050T5 (es) | 2011-02-15 |
CN1735805A (zh) | 2006-02-15 |
CA2505509C (en) | 2013-08-20 |
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