DE60328212D1 - Verfahren zur herstellung von alpha herpes virus resistenten säugetieren, mit diesem verfahren hergestellte säugetiere sowie ihre nachkommen - Google Patents
Verfahren zur herstellung von alpha herpes virus resistenten säugetieren, mit diesem verfahren hergestellte säugetiere sowie ihre nachkommenInfo
- Publication number
- DE60328212D1 DE60328212D1 DE60328212T DE60328212T DE60328212D1 DE 60328212 D1 DE60328212 D1 DE 60328212D1 DE 60328212 T DE60328212 T DE 60328212T DE 60328212 T DE60328212 T DE 60328212T DE 60328212 D1 DE60328212 D1 DE 60328212D1
- Authority
- DE
- Germany
- Prior art keywords
- mammals
- herpes virus
- success
- manufactured
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000124008 Mammalia Species 0.000 title 2
- 241001529453 unidentified herpesvirus Species 0.000 title 1
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 108700019146 Transgenes Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 210000004602 germ cell Anatomy 0.000 abstract 1
- 230000006801 homologous recombination Effects 0.000 abstract 1
- 238000002744 homologous recombination Methods 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0212775A FR2845692A1 (fr) | 2002-10-15 | 2002-10-15 | Procede pour produire un mammifere rendu resistant a une infection par un alpha herpes virus par transgenese germinale ainsi que mammifere obtenu par la mise en oeuvre de ce procede |
| PCT/FR2003/003024 WO2004035775A2 (fr) | 2002-10-15 | 2003-10-14 | Procede pour produire un mammifere rendu resistant a une infection par un alpha herpes virus ainsi que mammifere obtenu par la mise en oeuvre de ce procede et descendant d'un tel mammifere |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60328212D1 true DE60328212D1 (de) | 2009-08-13 |
Family
ID=32039728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60328212T Expired - Fee Related DE60328212D1 (de) | 2002-10-15 | 2003-10-14 | Verfahren zur herstellung von alpha herpes virus resistenten säugetieren, mit diesem verfahren hergestellte säugetiere sowie ihre nachkommen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060272040A1 (de) |
| EP (1) | EP1551222B1 (de) |
| CN (1) | CN1705436A (de) |
| AT (1) | ATE434933T1 (de) |
| AU (1) | AU2003288321A1 (de) |
| BR (1) | BR0315394A (de) |
| CA (1) | CA2501340A1 (de) |
| DE (1) | DE60328212D1 (de) |
| FR (1) | FR2845692A1 (de) |
| MX (1) | MXPA05003322A (de) |
| WO (1) | WO2004035775A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102676580B (zh) * | 2012-05-30 | 2013-06-19 | 扬州大学 | 高免疫原性单纯疱疹病毒gG1转基因花生的制备方法 |
| CN105251000B (zh) * | 2014-09-30 | 2018-12-14 | 普莱柯生物工程股份有限公司 | 猪伪狂犬病病毒疫苗组合物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866755A (en) * | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| US6291207B1 (en) * | 1995-07-28 | 2001-09-18 | Northwestern University | Herpes virus entry receptor protein |
| EP0948543A1 (de) * | 1996-12-12 | 1999-10-13 | Genentech, Inc. | Hemv-polyptide und ihre verwendung |
| EP1002864A1 (de) * | 1998-11-10 | 2000-05-24 | Universita' degli studi di Bologna | HIgR und relatierte V Domäne zur Herstellung eines Arzneimittels zur Vorbeugung oder Behandlung von HSV-1, HSV-2 und BHV Infektionen |
| WO2001079496A2 (en) * | 2000-03-13 | 2001-10-25 | La Jolla Institute For Allergy And Immunology | Ligand for herpes simplex virus entry mediator and methods of use |
| JP2004528008A (ja) * | 2000-10-05 | 2004-09-16 | イミュネックス・コーポレーション | ネクチンポリペプチド、ポリヌクレオチド、該ポリペプチドおよびポリヌクレオチドを作成し、そして使用する方法 |
-
2002
- 2002-10-15 FR FR0212775A patent/FR2845692A1/fr active Pending
-
2003
- 2003-10-14 DE DE60328212T patent/DE60328212D1/de not_active Expired - Fee Related
- 2003-10-14 MX MXPA05003322A patent/MXPA05003322A/es not_active Application Discontinuation
- 2003-10-14 US US10/530,539 patent/US20060272040A1/en not_active Abandoned
- 2003-10-14 EP EP03780222A patent/EP1551222B1/de not_active Expired - Lifetime
- 2003-10-14 CN CNA2003801014942A patent/CN1705436A/zh active Pending
- 2003-10-14 BR BR0315394-0A patent/BR0315394A/pt not_active IP Right Cessation
- 2003-10-14 CA CA002501340A patent/CA2501340A1/fr not_active Abandoned
- 2003-10-14 WO PCT/FR2003/003024 patent/WO2004035775A2/fr not_active Application Discontinuation
- 2003-10-14 AT AT03780222T patent/ATE434933T1/de not_active IP Right Cessation
- 2003-10-14 AU AU2003288321A patent/AU2003288321A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05003322A (es) | 2006-02-10 |
| WO2004035775A3 (fr) | 2004-06-17 |
| EP1551222B1 (de) | 2009-07-01 |
| AU2003288321A8 (en) | 2004-05-04 |
| FR2845692A1 (fr) | 2004-04-16 |
| EP1551222A2 (de) | 2005-07-13 |
| AU2003288321A1 (en) | 2004-05-04 |
| CN1705436A (zh) | 2005-12-07 |
| US20060272040A1 (en) | 2006-11-30 |
| ATE434933T1 (de) | 2009-07-15 |
| WO2004035775A2 (fr) | 2004-04-29 |
| BR0315394A (pt) | 2005-10-11 |
| CA2501340A1 (fr) | 2004-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |