DE60326930D1 - Darreichungsformen für dna - Google Patents
Darreichungsformen für dnaInfo
- Publication number
- DE60326930D1 DE60326930D1 DE60326930T DE60326930T DE60326930D1 DE 60326930 D1 DE60326930 D1 DE 60326930D1 DE 60326930 T DE60326930 T DE 60326930T DE 60326930 T DE60326930 T DE 60326930T DE 60326930 D1 DE60326930 D1 DE 60326930D1
- Authority
- DE
- Germany
- Prior art keywords
- dna
- skin
- present
- devices
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000008177 pharmaceutical agent Substances 0.000 abstract 3
- 229920005862 polyol Polymers 0.000 abstract 2
- 150000003077 polyols Chemical class 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 108010041986 DNA Vaccines Proteins 0.000 abstract 1
- 229940021995 DNA vaccine Drugs 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000003413 degradative effect Effects 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 239000006104 solid solution Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0201736.6A GB0201736D0 (en) | 2002-01-25 | 2002-01-25 | DNA dosage forms |
| PCT/GB2003/000282 WO2003061636A2 (en) | 2002-01-25 | 2003-01-23 | Dna dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60326930D1 true DE60326930D1 (de) | 2009-05-14 |
Family
ID=9929749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60326930T Expired - Fee Related DE60326930D1 (de) | 2002-01-25 | 2003-01-23 | Darreichungsformen für dna |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050080028A1 (enExample) |
| EP (1) | EP1467720B1 (enExample) |
| JP (1) | JP2005526016A (enExample) |
| AT (1) | ATE427105T1 (enExample) |
| AU (1) | AU2003202685A1 (enExample) |
| CA (1) | CA2473679A1 (enExample) |
| DE (1) | DE60326930D1 (enExample) |
| ES (1) | ES2322572T3 (enExample) |
| GB (1) | GB0201736D0 (enExample) |
| WO (1) | WO2003061636A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| AU2004268616B2 (en) | 2003-08-25 | 2010-10-07 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
| CA2542874A1 (en) * | 2003-10-23 | 2005-05-12 | Alza Corporation | Compositions of stabilized dna for coating microprojections |
| US7591806B2 (en) * | 2004-05-18 | 2009-09-22 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| DE602005025138D1 (de) | 2004-08-16 | 2011-01-13 | Fuctional Microstructures Ltd | Verfahren zur herstellung einer mikronadel oder eines mikroimplantats |
| US8048017B2 (en) * | 2005-05-18 | 2011-11-01 | Bai Xu | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| US8043250B2 (en) * | 2005-05-18 | 2011-10-25 | Nanomed Devices, Inc. | High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances |
| JP2009502261A (ja) * | 2005-07-25 | 2009-01-29 | ナノテクノロジー ビクトリア ピーティーワイ リミテッド | マイクロアレイデバイス |
| CA2629193C (en) | 2005-11-18 | 2016-03-29 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
| US10525246B2 (en) | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
| US20080214987A1 (en) * | 2006-12-22 | 2008-09-04 | Nanomed Devices, Inc. | Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances |
| US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
| CN103717249B (zh) | 2011-06-15 | 2017-03-22 | 克洛恩泰克制药股份公司 | 注射针和装置 |
| KR101314091B1 (ko) * | 2011-07-26 | 2013-10-04 | 연세대학교 산학협력단 | 치료 부위내 경피 유전자 전달을 위한 일렉트로 마이크로니들 집적체 및 이의 제조방법 |
| JP2013052202A (ja) * | 2011-09-01 | 2013-03-21 | Kosumedei Seiyaku Kk | Ｄｎａワクチンマイクロニードル |
| WO2013076305A1 (en) * | 2011-11-25 | 2013-05-30 | Danmarks Tekniske Universitet | Formulation of solid nano-sized particles in a gel-forming system |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0832638B2 (ja) * | 1989-05-25 | 1996-03-29 | カイロン コーポレイション | サブミクロン油滴乳剤を含んで成るアジュバント製剤 |
| ATE235558T1 (de) * | 1989-06-26 | 2003-04-15 | Powderject Vaccines Inc | Transformation von tierischen somatischen zellen mittels partikeln |
| US5697901A (en) * | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| WO1994023738A1 (en) * | 1993-04-19 | 1994-10-27 | Medisorb Technologies International L.P. | Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression |
| US5804566A (en) * | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| AU705889B2 (en) * | 1993-08-26 | 1999-06-03 | Regents Of The University Of California, The | Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory peptides |
| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| DE69531992T2 (de) * | 1994-08-04 | 2004-07-22 | Elan Drug Delivery Ltd., Ruddington | Feste verabreichungssysteme zur gesteuerten freisetzung von darin eingebauten molekülen sowie verfahren zu deren herstellung |
| JP4386965B2 (ja) * | 1996-04-26 | 2009-12-16 | メルク エンド カンパニー インコーポレーテッド | Ｄｎａワクチン製剤 |
| EP1100579B1 (en) * | 1998-07-13 | 2015-09-02 | Inovio Pharmaceuticals, Inc. | Skin and muscle-targeted gene therapy by pulsed electrical field |
| CA2372409C (en) * | 1999-01-28 | 2005-03-29 | Alan D. King | Delivery of macromolecules into cells |
| US6713291B2 (en) * | 1999-01-28 | 2004-03-30 | Alan D. King | Electrodes coated with treating agent and uses thereof |
| US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6835184B1 (en) * | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
| US20020002136A1 (en) * | 2000-06-28 | 2002-01-03 | Hebert Rolland F. | Salts of glutathione |
| CA2414926A1 (en) * | 2000-07-07 | 2002-01-17 | Corixa Corporation | Microspheres and adjuvants for dna vaccine delivery |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| DE60233939D1 (de) * | 2001-04-20 | 2009-11-19 | Alza Corp | Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält |
-
2002
- 2002-01-25 GB GBGB0201736.6A patent/GB0201736D0/en not_active Ceased
-
2003
- 2003-01-23 DE DE60326930T patent/DE60326930D1/de not_active Expired - Fee Related
- 2003-01-23 WO PCT/GB2003/000282 patent/WO2003061636A2/en not_active Ceased
- 2003-01-23 EP EP03701595A patent/EP1467720B1/en not_active Expired - Lifetime
- 2003-01-23 AU AU2003202685A patent/AU2003202685A1/en not_active Abandoned
- 2003-01-23 ES ES03701595T patent/ES2322572T3/es not_active Expired - Lifetime
- 2003-01-23 AT AT03701595T patent/ATE427105T1/de not_active IP Right Cessation
- 2003-01-23 JP JP2003561581A patent/JP2005526016A/ja active Pending
- 2003-01-23 CA CA002473679A patent/CA2473679A1/en not_active Abandoned
- 2003-01-23 US US10/502,285 patent/US20050080028A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005526016A (ja) | 2005-09-02 |
| GB0201736D0 (en) | 2002-03-13 |
| CA2473679A1 (en) | 2003-07-31 |
| ATE427105T1 (de) | 2009-04-15 |
| ES2322572T3 (es) | 2009-06-23 |
| EP1467720B1 (en) | 2009-04-01 |
| WO2003061636A2 (en) | 2003-07-31 |
| AU2003202685A1 (en) | 2003-09-02 |
| US20050080028A1 (en) | 2005-04-14 |
| WO2003061636A3 (en) | 2003-11-27 |
| EP1467720A2 (en) | 2004-10-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60326930D1 (de) | Darreichungsformen für dna | |
| BRPI0707845A8 (pt) | dispositivo de envio de droga | |
| BR0212434A (pt) | Dispositivos médicos contendo análogos de rapamicina | |
| CY1121467T1 (el) | Συστημα οφθαλμικης αποδεσμευσης φαρμακου που περιεχει φωσφολιπιδιο και χοληστερολη | |
| IL258702B (en) | A pump system for use with organ care systems | |
| IL183606A0 (en) | Medical device | |
| WO2007019539A3 (en) | Methods and devices for delivering agents across biological barriers | |
| BRPI0416132A (pt) | sistema e método para liberação de vacina transdérmica | |
| BR0001919A (pt) | Composição de creme de limpeza de pele de modo que forme espuma, e, sistema de limpeza espumante de pele. | |
| ATE434983T1 (de) | Vorrichtung zur elastischen stabilisierung von wirbelkörpern | |
| BRPI0507175A (pt) | sistema e método para dispensa de droga adaptativa | |
| AR063561A1 (es) | Dispositivos oculares y metodos para fabricar y utilizar los mismos | |
| BRPI0516718B8 (pt) | formulação de liberação modificada de ibuprofeno fornecendo liberação imediata e prolongada do fármaco | |
| BRPI0817482B8 (pt) | uso de um anticorpo do receptor da interleucina-6 (il-6) no tratamento da doença do enxerto versus hospedeiro (gvhd) | |
| AU2003297848A8 (en) | High viscosity liquid controlled delivery system and medical or surgical device | |
| NO20093471L (no) | Kanyle- og avgivelsesanordning | |
| ITVA20110027A1 (it) | Composizioni per la cura della persona | |
| BRPI0415986A (pt) | método e aparelho para reduzir a incidência do uso de tabaco | |
| BRPI0407845A (pt) | formulação intranasal de rotigotina | |
| ITMI20000300A0 (it) | Nebulizzatore medico per liquido da utilizzare nella terapia respiratoria e altre applicazioni | |
| ATE509637T1 (de) | Temperaturgesteuerte verabreichungssysteme | |
| SE0202315L (sv) | Anordning för att medelst beninduktivt eller bioaktivt medel inducera ben och/eller öka stabiliteten för implantat i käkben samt implantat härför | |
| DK1663347T3 (da) | Afereseindretning | |
| SE0103276L (sv) | Anordning för administrering av salva till en hudyta | |
| AR054435A1 (es) | Agente para profilaxis o terapia contra la depresion o desorden de ansiedad |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |