DE60326320D1 - Zusammensetzung zur inhalation - Google Patents

Zusammensetzung zur inhalation

Info

Publication number
DE60326320D1
DE60326320D1 DE60326320T DE60326320T DE60326320D1 DE 60326320 D1 DE60326320 D1 DE 60326320D1 DE 60326320 T DE60326320 T DE 60326320T DE 60326320 T DE60326320 T DE 60326320T DE 60326320 D1 DE60326320 D1 DE 60326320D1
Authority
DE
Germany
Prior art keywords
inhalation
composition
formoterol
budesonide
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60326320T
Other languages
German (de)
English (en)
Inventor
Nayna Govind
Maria Marlow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20286853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60326320(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60326320D1 publication Critical patent/DE60326320D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Networks Using Active Elements (AREA)
  • Pyrane Compounds (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
DE60326320T 2002-02-01 2003-01-29 Zusammensetzung zur inhalation Expired - Lifetime DE60326320D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0200312A SE0200312D0 (sv) 2002-02-01 2002-02-01 Novel composition
PCT/SE2003/000156 WO2003063842A1 (en) 2002-02-01 2003-01-29 Composition for inhalation

Publications (1)

Publication Number Publication Date
DE60326320D1 true DE60326320D1 (de) 2009-04-09

Family

ID=20286853

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60326320T Expired - Lifetime DE60326320D1 (de) 2002-02-01 2003-01-29 Zusammensetzung zur inhalation
DE60332067T Expired - Lifetime DE60332067D1 (de) 2002-02-01 2003-01-29 Neuartige Zusammensetzung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60332067T Expired - Lifetime DE60332067D1 (de) 2002-02-01 2003-01-29 Neuartige Zusammensetzung

Country Status (27)

Country Link
US (8) US7759328B2 (enExample)
EP (2) EP1474117B1 (enExample)
JP (2) JP2005521663A (enExample)
KR (2) KR100947168B1 (enExample)
CN (1) CN1287774C (enExample)
AT (2) ATE423552T1 (enExample)
AU (1) AU2003206289B2 (enExample)
BR (1) BR0307193A (enExample)
CA (1) CA2474479C (enExample)
CO (1) CO5611098A2 (enExample)
CY (2) CY1109030T1 (enExample)
DE (2) DE60326320D1 (enExample)
DK (2) DK1474117T3 (enExample)
ES (2) ES2321180T3 (enExample)
IL (1) IL163160A (enExample)
IS (2) IS7360A (enExample)
MX (1) MXPA04007295A (enExample)
NO (1) NO337006B1 (enExample)
NZ (1) NZ534452A (enExample)
PL (1) PL211836B1 (enExample)
PT (2) PT2036549E (enExample)
RU (1) RU2301673C2 (enExample)
SE (1) SE0200312D0 (enExample)
SI (2) SI2036549T1 (enExample)
UA (1) UA79445C2 (enExample)
WO (1) WO2003063842A1 (enExample)
ZA (1) ZA200406086B (enExample)

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SE0200312D0 (sv) * 2002-02-01 2002-02-01 Astrazeneca Ab Novel composition
BRPI0606736A2 (pt) * 2005-02-11 2009-07-21 Argenta Discovery Ltd combinação de compostos e esteróides de metilxantina para tratar doenças respiratórias crÈnicas
US9084799B2 (en) 2005-02-11 2015-07-21 Pulmagen Therapeutics (Synergy) Limited Inhaled combination therapy
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
GB0604141D0 (en) * 2006-03-01 2006-04-12 Arrow Int Ltd Nebulizer formulation
GB0712454D0 (en) * 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US20130160761A1 (en) * 2008-11-04 2013-06-27 Cipla Limited Pharmaceutical Aerosol Composition
NZ574666A (en) * 2009-02-05 2009-04-30 Nexus6 Ltd A medicament inhaler holder that uses optical means to count and display the number of doses used
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
AP3141A (en) 2009-11-25 2015-02-28 Boehringer Ingelheim Int Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
CN105412122A (zh) 2010-07-16 2016-03-23 希普拉有限公司 包含r(+)布地奈德和一种或多种支气管扩张剂的药物组合物
WO2012016845A2 (en) * 2010-08-03 2012-02-09 Chiesi Farmaceutici S.P.A. Pharmaceutical formulation comprising a phosphodiesterase inhibitor
EP2618816A4 (en) * 2010-09-22 2014-10-29 Map Pharmaceuticals Ltd AEROSOL COMPOSITION FOR THE ADMINISTRATION OF MEDICAMENTS
US20120204871A1 (en) 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
TWI399202B (zh) * 2011-03-17 2013-06-21 Intech Biopharm Ltd 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
MY171271A (en) 2011-08-19 2019-10-07 Intech Biopharm Ltd Method for preparing metered dose sprayed inhaler for treating respiratory disease
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
GB201321712D0 (en) 2013-12-09 2014-01-22 Pharmachemie Bv Dry Powder Inhaler
GB201321717D0 (en) 2013-12-09 2014-01-22 Pharmachemie Bv Inhalable Medicaments
CN106456913B (zh) 2014-05-07 2019-08-30 勃林格殷格翰国际有限公司 喷雾器和容器
DK3139979T3 (da) 2014-05-07 2023-10-09 Boehringer Ingelheim Int Enhed, forstøver og fremgangsmåde
EP3139984B1 (en) 2014-05-07 2021-04-28 Boehringer Ingelheim International GmbH Nebulizer
WO2016018892A1 (en) * 2014-07-29 2016-02-04 3M Innovative Properties Company Method of preparing a pharmaceutical composition
ES2796177T5 (es) 2015-12-04 2024-10-29 Mexichem Fluor Sa De Cv Composición farmacéutica
CN106581010B (zh) * 2016-12-28 2019-03-05 四川普锐特医药科技有限责任公司 一种气溶胶制剂及定量吸入气雾剂
CA3073195A1 (en) 2017-08-15 2019-02-21 Nephron Pharmaceuticals Corporation Aqueous nebulization composition
JP7470646B2 (ja) 2018-06-14 2024-04-18 アストラゼネカ・ユーケイ・リミテッド コルチコステロイド医薬組成物を用いて喘息の症状を治療および予防するための方法
JP7402631B2 (ja) 2018-08-27 2023-12-21 帝人株式会社 極細炭素繊維混合物、その製造方法、及び炭素系導電助剤
CN109464429B (zh) * 2018-12-13 2021-04-27 上海方予健康医药科技有限公司 一种吸入压力定量气雾剂药物组合物及其制备方法
CN112137957B (zh) 2019-06-26 2022-07-29 长风药业股份有限公司 一种药用吸入气雾剂及其制备方法
CN112972384B (zh) * 2019-12-02 2022-03-18 长风药业股份有限公司 一种格隆溴铵和茚达特罗原料药微粉混合物的制备方法
CN117357485B (zh) * 2023-11-01 2024-09-24 山东京卫制药有限公司 一种改良的可吸入的载体颗粒及应用

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SE9603669D0 (sv) 1996-10-08 1996-10-08 Astra Ab New combination
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SE9703407D0 (sv) 1997-09-19 1997-09-19 Astra Ab New use
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SE9802073D0 (sv) * 1998-06-11 1998-06-11 Astra Ab New use
ATE283033T1 (de) 1998-07-24 2004-12-15 Jago Res Ag Medizinische aerosolformulierungen
US6004537A (en) 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
SE9900834D0 (sv) 1999-03-09 1999-03-09 Astra Ab Novel combination
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009584D0 (en) 2000-04-18 2000-06-07 Glaxo Group Ltd Pharmaceutical compositions
GB0012260D0 (en) * 2000-05-19 2000-07-12 Astrazeneca Ab Novel composition
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SE0200312D0 (sv) * 2002-02-01 2002-02-01 Astrazeneca Ab Novel composition

Also Published As

Publication number Publication date
CY1109030T1 (el) 2014-07-02
US20210069215A1 (en) 2021-03-11
DK2036549T3 (da) 2010-07-12
CN1287774C (zh) 2006-12-06
JP2005521663A (ja) 2005-07-21
US20120216802A1 (en) 2012-08-30
CO5611098A2 (es) 2006-02-28
NO337006B1 (no) 2015-12-21
CA2474479A1 (en) 2003-08-07
AU2003206289B2 (en) 2007-09-06
SI1474117T1 (sl) 2009-06-30
US8143239B2 (en) 2012-03-27
RU2004122921A (ru) 2005-06-10
KR20090125857A (ko) 2009-12-07
DK1474117T3 (da) 2009-05-25
ES2321180T3 (es) 2009-06-03
WO2003063842A1 (en) 2003-08-07
EP2036549B1 (en) 2010-04-07
JP5259636B2 (ja) 2013-08-07
IS7360A (is) 2004-07-21
ES2342509T3 (es) 2010-07-07
HK1126684A1 (en) 2009-09-11
RU2301673C2 (ru) 2007-06-27
US10166247B2 (en) 2019-01-01
EP2036549A1 (en) 2009-03-18
CN1625392A (zh) 2005-06-08
KR100947168B1 (ko) 2010-03-12
DE60332067D1 (de) 2010-05-20
US8575137B2 (en) 2013-11-05
MXPA04007295A (es) 2004-10-29
PL211836B1 (pl) 2012-06-29
IS9028A (is) 2013-04-16
CY1110081T1 (el) 2015-01-14
CA2474479C (en) 2011-04-05
SI2036549T1 (sl) 2010-07-30
US20140286878A1 (en) 2014-09-25
IL163160A (en) 2013-12-31
US7759328B2 (en) 2010-07-20
ZA200406086B (en) 2006-01-25
PL372118A1 (en) 2005-07-11
US20170368078A1 (en) 2017-12-28
NO20043458L (no) 2004-08-19
JP2010132695A (ja) 2010-06-17
UA79445C2 (en) 2007-06-25
US20050089478A1 (en) 2005-04-28
EP1474117B1 (en) 2009-02-25
PT1474117E (pt) 2009-04-24
ATE463241T1 (de) 2010-04-15
BR0307193A (pt) 2004-11-03
US20100275913A1 (en) 2010-11-04
ATE423552T1 (de) 2009-03-15
US20160022703A1 (en) 2016-01-28
PT2036549E (pt) 2010-06-22
IS2960B (is) 2017-02-15
NZ534452A (en) 2006-01-27
US20190216828A1 (en) 2019-07-18
US11311558B2 (en) 2022-04-26
WO2003063842A9 (en) 2004-04-22
EP1474117A1 (en) 2004-11-10
SE0200312D0 (sv) 2002-02-01
KR20040081757A (ko) 2004-09-22

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