DE60320770D1 - Verfahren zur verabreichung von buprenorphin zur behandlung von depression - Google Patents
Verfahren zur verabreichung von buprenorphin zur behandlung von depressionInfo
- Publication number
- DE60320770D1 DE60320770D1 DE60320770T DE60320770T DE60320770D1 DE 60320770 D1 DE60320770 D1 DE 60320770D1 DE 60320770 T DE60320770 T DE 60320770T DE 60320770 T DE60320770 T DE 60320770T DE 60320770 D1 DE60320770 D1 DE 60320770D1
- Authority
- DE
- Germany
- Prior art keywords
- depression
- buprenorphine
- administration
- treatment
- patients suffering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 title abstract 4
- 229960001736 buprenorphine Drugs 0.000 title abstract 4
- 208000020401 Depressive disease Diseases 0.000 title 1
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000037317 transdermal delivery Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36635802P | 2002-03-20 | 2002-03-20 | |
| PCT/US2003/008796 WO2003079945A1 (en) | 2002-03-20 | 2003-03-20 | Method of administering buprenorphine to treat depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60320770D1 true DE60320770D1 (de) | 2008-06-19 |
Family
ID=28454789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60320770T Expired - Lifetime DE60320770D1 (de) | 2002-03-20 | 2003-03-20 | Verfahren zur verabreichung von buprenorphin zur behandlung von depression |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20030181475A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1485051B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2005528359A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE394097T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003224742A1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1108217T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60320770D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1485051T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2305457T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1485051E (cg-RX-API-DMAC7.html) |
| SI (1) | SI1485051T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003079945A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| EP1913938A1 (en) * | 2002-12-13 | 2008-04-23 | Euro-Celtique S.A. | Transdermal buprenorphine dosage regimen for analgesia |
| US7270830B2 (en) * | 2002-12-13 | 2007-09-18 | Purdue Pharma L.P. | Transdermal buprenorphine dosage regimen for analgesia |
| US8790689B2 (en) | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| BRPI0409945A (pt) | 2003-04-30 | 2006-04-25 | Purdue Pharma Lp | forma de dosagem resistente à alteração |
| DE602004009449T2 (de) | 2003-07-25 | 2008-07-24 | Euro-Celtique S.A. | Behandlung von entzug |
| DE10340428B4 (de) * | 2003-09-02 | 2015-02-12 | Acino Ag | Opioides Analgetikum enthaltende transdermale Formulierung |
| FR2865650B1 (fr) * | 2004-01-30 | 2008-06-13 | Biocortech | Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil |
| DE102004045599A1 (de) * | 2004-09-17 | 2006-03-23 | Grünenthal GmbH | System zur sequentiellen, transdermalen Verabreichung von systemisch wirksamen Substanzen |
| DE102005007859A1 (de) * | 2005-02-21 | 2006-08-24 | Lts Lohmann Therapie-Systeme Ag | Vefahren für eine medikamentöse Kombinations-Behandlung, sowie hierfür geeignete Arzneimittel-Kombinationen |
| DE102006011340A1 (de) * | 2006-03-09 | 2007-09-20 | Grünenthal GmbH | Wirkstoffhaltige Pflaster mit verbesserter Handhabung |
| HUE043963T2 (hu) | 2009-12-04 | 2019-09-30 | Alkermes Pharma Ireland Ltd | Morfinán származékok gyógyszer-túladagolás kezelésére |
| EP2608670B1 (en) | 2010-08-23 | 2018-10-31 | Alkermes Pharma Ireland Limited | Methods for treating antipsychotic-induced weight gain |
| US10813925B2 (en) | 2011-09-19 | 2020-10-27 | Carmel—Haifa University Economic Corporation Ltd. | Buprenorphine for the treatment of acute suicidality |
| US10195191B2 (en) | 2011-12-15 | 2019-02-05 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| SMT201800664T1 (it) * | 2011-12-15 | 2019-01-11 | Alkermes Pharma Ireland Ltd | Samidorphan (alks 33) in combinazione con buprenorfina per il trattamento di disturbi depressivi |
| CA2858808C (en) * | 2011-12-15 | 2017-04-18 | Alkermes Pharma Ireland Limited | Samidorphan (alks 33) in combination with opioid agonists |
| US9656961B2 (en) | 2013-05-24 | 2017-05-23 | Alkermes Pharma Ireland Limited | Methods for treating depressive symptoms |
| ES2770978T3 (es) | 2013-05-24 | 2020-07-06 | Alkermes Pharma Ireland Ltd | Análogos de morfanos y morfinanos y métodos de uso |
| CA2933733A1 (en) | 2013-12-20 | 2015-06-25 | Connie Sanchez Morillo | Use of an opioid receptor antagonist with kappa-activity and vortioxetine for treatment of depressive disorder with melancholic features |
| WO2022101444A1 (en) | 2020-11-12 | 2022-05-19 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806341A (en) * | 1985-02-25 | 1989-02-21 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration |
| US5026556A (en) * | 1988-11-10 | 1991-06-25 | Norwich Eaton Pharmaceuticals, Inc. | Compositions for the transdermal delivery of pharmaceutical actives |
| US4956171A (en) * | 1989-07-21 | 1990-09-11 | Paco Pharmaceutical Services, Inc. | Transdermal drug delivery using a dual permeation enhancer and method of performing the same |
| US5240711A (en) * | 1989-11-29 | 1993-08-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system comprising as active component buprenorphine |
| AU637496B2 (en) * | 1990-04-24 | 1993-05-27 | Teijin Limited | Plaster |
| US5069909A (en) * | 1990-06-20 | 1991-12-03 | Cygnus Therapeutic Systems | Transdermal administration of buprenorphine |
| US5512593A (en) * | 1993-03-02 | 1996-04-30 | John S. Nagle | Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor |
| US5613958A (en) * | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
| ATE218328T1 (de) * | 1996-03-25 | 2002-06-15 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system mit geringer applikationsdicke und hoher flexibilität sowie herstellungsverfahren |
| US6787149B1 (en) * | 1996-12-12 | 2004-09-07 | El Khoury And Stein Ltd. | Topical application of opioid analgesic drugs such as morphine |
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
| DE19738855C2 (de) * | 1997-09-05 | 2001-01-04 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht |
| DE19746191C2 (de) * | 1997-10-18 | 2000-05-18 | Lohmann Therapie Syst Lts | Verfahren zur Anwendung eines Wirkstoff enthaltenden Pflasters zur Bekämpfung oder Linderung einer Sucht |
| EP1061924A1 (en) * | 1998-03-09 | 2000-12-27 | Trustees Of Tufts College | Treatment of compulsive behaviours in man and animals |
| DE19840758A1 (de) * | 1998-09-07 | 2000-03-09 | Liedtke Pharmed Gmbh | Systemische Therapie von Schmerz- und depressiver Befindlichkeit |
-
2003
- 2003-03-20 PT PT03721427T patent/PT1485051E/pt unknown
- 2003-03-20 DK DK03721427T patent/DK1485051T3/da active
- 2003-03-20 US US10/394,425 patent/US20030181475A1/en not_active Abandoned
- 2003-03-20 DE DE60320770T patent/DE60320770D1/de not_active Expired - Lifetime
- 2003-03-20 AT AT03721427T patent/ATE394097T1/de active
- 2003-03-20 JP JP2003577780A patent/JP2005528359A/ja active Pending
- 2003-03-20 EP EP03721427A patent/EP1485051B1/en not_active Expired - Lifetime
- 2003-03-20 ES ES03721427T patent/ES2305457T3/es not_active Expired - Lifetime
- 2003-03-20 AU AU2003224742A patent/AU2003224742A1/en not_active Abandoned
- 2003-03-20 WO PCT/US2003/008796 patent/WO2003079945A1/en not_active Ceased
- 2003-03-20 SI SI200331272T patent/SI1485051T1/sl unknown
-
2008
- 2008-07-28 CY CY20081100780T patent/CY1108217T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1485051A4 (en) | 2006-05-24 |
| SI1485051T1 (sl) | 2008-10-31 |
| DK1485051T3 (da) | 2008-09-08 |
| US20030181475A1 (en) | 2003-09-25 |
| JP2005528359A (ja) | 2005-09-22 |
| EP1485051A1 (en) | 2004-12-15 |
| ATE394097T1 (de) | 2008-05-15 |
| CY1108217T1 (el) | 2014-02-12 |
| EP1485051B1 (en) | 2008-05-07 |
| PT1485051E (pt) | 2008-07-09 |
| ES2305457T3 (es) | 2008-11-01 |
| AU2003224742A1 (en) | 2003-10-08 |
| WO2003079945A1 (en) | 2003-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |