DE60318297D1 - Enon reduktase - Google Patents

Enon reduktase

Info

Publication number
DE60318297D1
DE60318297D1 DE60318297T DE60318297T DE60318297D1 DE 60318297 D1 DE60318297 D1 DE 60318297D1 DE 60318297 T DE60318297 T DE 60318297T DE 60318297 T DE60318297 T DE 60318297T DE 60318297 D1 DE60318297 D1 DE 60318297D1
Authority
DE
Germany
Prior art keywords
reductase
enon
nadph
producing
optimum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60318297T
Other languages
English (en)
Other versions
DE60318297T2 (de
Inventor
Michihiko Kataoka
Sakayu Shimizu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Application granted granted Critical
Publication of DE60318297D1 publication Critical patent/DE60318297D1/de
Publication of DE60318297T2 publication Critical patent/DE60318297T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60318297T 2002-02-22 2003-02-14 Enonreduktase Expired - Lifetime DE60318297T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02003967 2002-02-22
EP02003967 2002-02-22
PCT/EP2003/001473 WO2003070924A1 (en) 2002-02-22 2003-02-14 Enone reductase

Publications (2)

Publication Number Publication Date
DE60318297D1 true DE60318297D1 (de) 2008-02-07
DE60318297T2 DE60318297T2 (de) 2008-05-08

Family

ID=27741105

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60318297T Expired - Lifetime DE60318297T2 (de) 2002-02-22 2003-02-14 Enonreduktase

Country Status (10)

Country Link
US (1) US7202068B2 (de)
EP (1) EP1476544B1 (de)
JP (1) JP2005517442A (de)
KR (1) KR20040088511A (de)
CN (1) CN100523179C (de)
AT (1) ATE382081T1 (de)
AU (1) AU2003210271A1 (de)
CA (1) CA2474780A1 (de)
DE (1) DE60318297T2 (de)
WO (1) WO2003070924A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60313784D1 (de) * 2002-09-23 2007-06-21 Dsm Ip Assets Bv Enon reduktase gen und mikrobielle herstellung von levodion
WO2010075574A2 (en) 2008-12-25 2010-07-01 Codexis, Inc. Enone reductases
CN102559553B (zh) * 2012-01-08 2013-06-05 中国科学院成都生物研究所 一株无色杆菌及其不对称催化还原碳碳双键的方法
CN112143764B (zh) * 2020-09-24 2022-04-19 奥锐特药业股份有限公司 一种生物酶催化制备布瓦西坦中间体化合物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072715A (en) * 1974-08-21 1978-02-07 Hoffmann-La Roche Inc. Optically active cyclohexane derivatives
EP1074630B1 (de) * 1999-08-02 2012-01-18 DSM IP Assets B.V. Mikrobielle Herstellung von Levodione
JP4688313B2 (ja) * 2001-02-23 2011-05-25 ダイセル化学工業株式会社 新規なエノン還元酵素、その製造方法、およびこれを利用したα，β−不飽和ケトンの炭素−炭素２重結合を選択的に還元する方法

Also Published As

Publication number Publication date
US20050106696A1 (en) 2005-05-19
EP1476544A1 (de) 2004-11-17
KR20040088511A (ko) 2004-10-16
EP1476544B1 (de) 2007-12-26
JP2005517442A (ja) 2005-06-16
CN1636057A (zh) 2005-07-06
CN100523179C (zh) 2009-08-05
US7202068B2 (en) 2007-04-10
CA2474780A1 (en) 2003-08-28
ATE382081T1 (de) 2008-01-15
DE60318297T2 (de) 2008-05-08
WO2003070924A1 (en) 2003-08-28
AU2003210271A1 (en) 2003-09-09

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Legal Events

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