DE60312682D1 - Methode zur behandlung von rosacea durch topische verabreichung eines cyclohexanderivats - Google Patents
Methode zur behandlung von rosacea durch topische verabreichung eines cyclohexanderivatsInfo
- Publication number
- DE60312682D1 DE60312682D1 DE60312682T DE60312682T DE60312682D1 DE 60312682 D1 DE60312682 D1 DE 60312682D1 DE 60312682 T DE60312682 T DE 60312682T DE 60312682 T DE60312682 T DE 60312682T DE 60312682 D1 DE60312682 D1 DE 60312682D1
- Authority
- DE
- Germany
- Prior art keywords
- rosacea
- cyclohexanediol
- cyclohexideerivate
- treatment
- topical administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 4
- 241001303601 Rosacea Species 0.000 title abstract 3
- 201000004700 rosacea Diseases 0.000 title abstract 3
- 238000011200 topical administration Methods 0.000 title 1
- 239000011149 active material Substances 0.000 abstract 2
- PFURGBBHAOXLIO-UHFFFAOYSA-N cyclohexane-1,2-diol Chemical compound OC1CCCCC1O PFURGBBHAOXLIO-UHFFFAOYSA-N 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 208000005141 Otitis Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- PMMYEEVYMWASQN-IMJSIDKUSA-N cis-4-Hydroxy-L-proline Chemical compound O[C@@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-IMJSIDKUSA-N 0.000 abstract 1
- RLMGYIOTPQVQJR-UHFFFAOYSA-N cyclohexane-1,3-diol Chemical compound OC1CCCC(O)C1 RLMGYIOTPQVQJR-UHFFFAOYSA-N 0.000 abstract 1
- 208000019258 ear infection Diseases 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38837302P | 2002-06-12 | 2002-06-12 | |
| US388373P | 2002-06-12 | ||
| US10/430,917 US6723755B2 (en) | 2002-06-12 | 2003-05-07 | Method of treating rosacea |
| US430917 | 2003-05-07 | ||
| PCT/US2003/017999 WO2003105816A1 (en) | 2002-06-01 | 2003-06-09 | Method of treating rosacea by topical application of a cyclohexane derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60312682D1 true DE60312682D1 (de) | 2007-05-03 |
| DE60312682T2 DE60312682T2 (de) | 2007-12-06 |
Family
ID=29740021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60312682T Expired - Lifetime DE60312682T2 (de) | 2002-06-12 | 2003-06-09 | Methode zur behandlung von rosacea durch topische verabreichung eines cyclohexanderivats |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6723755B2 (de) |
| EP (1) | EP1515710B1 (de) |
| JP (1) | JP2005533060A (de) |
| AT (1) | ATE357225T1 (de) |
| AU (1) | AU2003238940A1 (de) |
| CA (1) | CA2486663C (de) |
| DE (1) | DE60312682T2 (de) |
| DK (1) | DK1515710T3 (de) |
| ES (1) | ES2279954T3 (de) |
| IL (2) | IL165369A (de) |
| PT (1) | PT1515710E (de) |
| WO (1) | WO2003105816A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| US7812057B2 (en) * | 2004-08-25 | 2010-10-12 | Molecular Research Center, Inc. | Cosmetic compositions |
| DK1791791T3 (da) * | 2004-09-27 | 2019-08-26 | Special Water Patents B V | Fremgangsmåder og sammensætninger til behandling af vand |
| US9579298B2 (en) * | 2004-12-02 | 2017-02-28 | Piotr Chomczynski | Antioxidant dietary supplement compositions and methods for maintaining healthy skin |
| EP1948236B1 (de) | 2005-09-27 | 2021-03-03 | Special Water Patents B.V. | Methoden und zusammensetzungen zur behandlung der haut |
| JP2009511568A (ja) * | 2005-10-13 | 2009-03-19 | ワラタ ファーマシューティカルズ， インコーポレイテッド | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
| US20100247693A1 (en) * | 2009-03-24 | 2010-09-30 | Marini Jan L | Cosmetic formulation to treat rosacea telangiectasia |
| JP2015521161A (ja) | 2012-04-25 | 2015-07-27 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 抗微生物特性を有するジシクロヘキシルメタノール誘導体の使用 |
| CN104487047A (zh) * | 2012-05-08 | 2015-04-01 | 默克专利股份有限公司 | 具有抗微生物性能的环己醇醚的用途 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0625045A4 (de) | 1992-02-07 | 1995-01-18 | Albert M Kligman | Verfahren zur behandlung von entzündlichen dermatosen. |
| US5641809A (en) | 1992-12-18 | 1997-06-24 | Lansinoh Laboratories, Inc. | Lanolin/lanolin acid ester skin treatment composition |
| US6028118A (en) | 1996-08-08 | 2000-02-22 | Les Laboratoires Aeterna Inc. | Methods of using extracts of shark cartilage |
| DE4423669C1 (de) | 1994-06-23 | 1996-02-22 | Schering Ag | Cyclohexanon-Derivate, Verfahren zu deren Herstellung und Zwischenprodukte des Verfahrens |
| FR2728166A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Composition topique contenant un antagoniste de substance p |
| FR2728258A1 (fr) | 1994-12-19 | 1996-06-21 | Oreal | Utilisation d'un derive de l'ethylene diamine dans une composition cosmetique ou dermatologique et composition contenant notamment un produit a effet secondaire irritant |
| FR2732221B1 (fr) | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue |
| US6060604A (en) | 1995-03-31 | 2000-05-09 | Florida State University | Pharmaceutical compounds comprising polyamines substituted with electron-affinic groups |
| US5654312A (en) | 1995-06-07 | 1997-08-05 | Andrulis Pharmaceuticals | Treatment of inflammatory and/or autoimmune dermatoses with thalidomide alone or in combination with other agents |
| FR2741262B1 (fr) | 1995-11-20 | 1999-03-05 | Oreal | Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene |
| US5885595A (en) | 1996-05-13 | 1999-03-23 | Elizabeth Arden Co., Division Of Conopco, Inc. | Cosmetic composition with a retinol fatty acid ester |
| US6294585B1 (en) | 1996-09-18 | 2001-09-25 | Applied Genetics Incorporated Dermatics | Treatment of neurodegenerative diseases |
| FR2754818B1 (fr) | 1996-10-23 | 1999-03-05 | Cird Galderma | Nouveaux derives bi-aromatiques du dibenzofuranne et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetique |
| SI0941221T1 (en) | 1996-11-20 | 2003-10-31 | Altana Pharma Ag | Substituted dihydrobenzofurans as pde inhibitors |
| US5945410A (en) | 1997-03-17 | 1999-08-31 | Wisconsin Alumni Research Foundation | 2-alkyl-19-nor-vitamin D compounds |
| WO1998052894A1 (en) * | 1997-05-23 | 1998-11-26 | F.Hoffmann-La Roche Ag | Cyclohexanediol derivatives |
| US6184422B1 (en) | 1998-02-26 | 2001-02-06 | Hoffman-La Roche Inc. | Cyclohexanediol derivatives |
| US5972993A (en) | 1998-03-20 | 1999-10-26 | Avon Products, Inc. | Composition and method for treating rosacea and sensitive skin with free radical scavengers |
| US6071541A (en) | 1998-07-31 | 2000-06-06 | Murad; Howard | Pharmaceutical compositions and methods for managing skin conditions |
| US5952372A (en) | 1998-09-17 | 1999-09-14 | Mcdaniel; William Robert | Method for treating rosacea using oral or topical ivermectin |
| US5994330A (en) | 1998-11-09 | 1999-11-30 | El Khoury; Georges F. | Topical application of muscarinic agents such as neostigmine for treatment of acne and other inflammatory conditions |
| US6071955A (en) | 1999-02-25 | 2000-06-06 | The Regents Of The University Of California | FXR, PPARA and LXRA activators to treat acne/acneiform conditions |
| EP1242352A2 (de) * | 1999-12-23 | 2002-09-25 | University Of Georgia Research Foundation, Inc. | Chalcone und ihre analoge als hemmende wirkstoffe für angiogenese und verwandte krankheiten |
| EP1181866A1 (de) * | 2000-08-14 | 2002-02-27 | Givaudan SA | Antibakterielle Zusammensetzung enthaltend Sandela |
-
2003
- 2003-05-07 US US10/430,917 patent/US6723755B2/en not_active Expired - Lifetime
- 2003-06-09 AU AU2003238940A patent/AU2003238940A1/en not_active Abandoned
- 2003-06-09 ES ES03734461T patent/ES2279954T3/es not_active Expired - Lifetime
- 2003-06-09 DE DE60312682T patent/DE60312682T2/de not_active Expired - Lifetime
- 2003-06-09 JP JP2004512722A patent/JP2005533060A/ja active Pending
- 2003-06-09 PT PT03734461T patent/PT1515710E/pt unknown
- 2003-06-09 DK DK03734461T patent/DK1515710T3/da active
- 2003-06-09 CA CA2486663A patent/CA2486663C/en not_active Expired - Lifetime
- 2003-06-09 AT AT03734461T patent/ATE357225T1/de active
- 2003-06-09 EP EP03734461A patent/EP1515710B1/de not_active Expired - Lifetime
- 2003-06-09 WO PCT/US2003/017999 patent/WO2003105816A1/en active Application Filing
-
2004
- 2004-11-24 IL IL165369A patent/IL165369A/en active IP Right Grant
-
2008
- 2008-03-03 IL IL189901A patent/IL189901A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| PT1515710E (pt) | 2007-04-30 |
| ATE357225T1 (de) | 2007-04-15 |
| CA2486663C (en) | 2012-04-10 |
| EP1515710A1 (de) | 2005-03-23 |
| IL165369A (en) | 2011-10-31 |
| US20030232893A1 (en) | 2003-12-18 |
| WO2003105816A1 (en) | 2003-12-24 |
| ES2279954T3 (es) | 2007-09-01 |
| EP1515710B1 (de) | 2007-03-21 |
| JP2005533060A (ja) | 2005-11-04 |
| CA2486663A1 (en) | 2003-12-24 |
| AU2003238940A1 (en) | 2003-12-31 |
| IL165369A0 (en) | 2006-01-15 |
| US6723755B2 (en) | 2004-04-20 |
| DK1515710T3 (da) | 2007-05-21 |
| IL189901A (en) | 2015-08-31 |
| DE60312682T2 (de) | 2007-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |