DE60310683D1 - Verfahren zur herstellung von 1-(mercaptomethyl)cyclopropan essigsäure - Google Patents

Verfahren zur herstellung von 1-(mercaptomethyl)cyclopropan essigsäure

Info

Publication number
DE60310683D1
DE60310683D1 DE60310683T DE60310683T DE60310683D1 DE 60310683 D1 DE60310683 D1 DE 60310683D1 DE 60310683 T DE60310683 T DE 60310683T DE 60310683 T DE60310683 T DE 60310683T DE 60310683 D1 DE60310683 D1 DE 60310683D1
Authority
DE
Germany
Prior art keywords
mercaptomethyl
cyclopropaneacetic acid
preparation
amide
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60310683T
Other languages
English (en)
Other versions
DE60310683T2 (de
Inventor
Wei Liu
Yuan Wang
Herika Marrugo
Sylvain Harper
D C Quan
Zhihong Nancy Zhou
Gregory Bydlinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delmar Chemicals Inc
Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2371048A external-priority patent/CA2371048C/en
Application filed by Delmar Chemicals Inc filed Critical Delmar Chemicals Inc
Application granted granted Critical
Publication of DE60310683D1 publication Critical patent/DE60310683D1/de
Publication of DE60310683T2 publication Critical patent/DE60310683T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
DE60310683T 2002-02-06 2003-02-05 Verfahren zur herstellung von 1-(mercaptomethyl)cyclopropan essigsäure Expired - Lifetime DE60310683T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US122541 1980-02-19
CA2371048A CA2371048C (en) 2002-02-06 2002-02-06 Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid
CA2371048 2002-02-06
US10/122,541 US6512140B1 (en) 2002-02-06 2002-04-15 Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid
PCT/CA2003/000165 WO2003066582A1 (en) 2002-02-06 2003-02-05 Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid

Publications (2)

Publication Number Publication Date
DE60310683D1 true DE60310683D1 (de) 2007-02-08
DE60310683T2 DE60310683T2 (de) 2007-10-11

Family

ID=27735483

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310683T Expired - Lifetime DE60310683T2 (de) 2002-02-06 2003-02-05 Verfahren zur herstellung von 1-(mercaptomethyl)cyclopropan essigsäure

Country Status (8)

Country Link
EP (1) EP1474386B1 (de)
JP (1) JP4308667B2 (de)
CN (1) CN1318400C (de)
AT (1) ATE349423T1 (de)
AU (1) AU2003244427A1 (de)
BR (1) BR0302902A (de)
DE (1) DE60310683T2 (de)
WO (1) WO2003066582A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110386888A (zh) * 2019-07-30 2019-10-29 上海红蓝医药科技有限公司 一种低成本、高收率的1-(巯甲基)环丙基乙酸生产工艺
CN111018756A (zh) * 2019-12-13 2020-04-17 山东益丰生化环保股份有限公司 一种2-2-二巯甲基-1-3-丙二硫醇的制备方法
CN114181121B (zh) * 2021-12-08 2024-04-26 江苏阿尔法药业股份有限公司 一种1-巯甲基环丙基乙酸的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0480717T3 (da) * 1990-10-12 1999-02-08 Merck Frosst Canada Inc Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister
CA2111372C (en) * 1992-12-22 2007-01-16 Robert N. Young Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists
CA2130723C (en) * 1993-09-03 2006-01-31 Wilhelm Quittmann Process for preparing y-mercaptocarboxylic acid derivatives
TW448160B (en) * 1993-12-28 2001-08-01 Merck & Co Inc Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists
US5523477A (en) * 1995-01-23 1996-06-04 Merck & Co., Inc. Process for the preparation of 1-(thiomethyl)-cyclopropaneacetic acid
CA2371048C (en) * 2002-02-06 2011-01-04 Delmar Chemicals Inc. Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid

Also Published As

Publication number Publication date
JP2005517009A (ja) 2005-06-09
EP1474386A1 (de) 2004-11-10
JP4308667B2 (ja) 2009-08-05
AU2003244427A1 (en) 2003-09-02
CN1628096A (zh) 2005-06-15
ATE349423T1 (de) 2007-01-15
CN1318400C (zh) 2007-05-30
EP1474386B1 (de) 2006-12-27
WO2003066582A1 (en) 2003-08-14
DE60310683T2 (de) 2007-10-11
BR0302902A (pt) 2004-07-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition