DE60303169D1 - Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System - Google Patents

Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System

Info

Publication number
DE60303169D1
DE60303169D1 DE60303169T DE60303169T DE60303169D1 DE 60303169 D1 DE60303169 D1 DE 60303169D1 DE 60303169 T DE60303169 T DE 60303169T DE 60303169 T DE60303169 T DE 60303169T DE 60303169 D1 DE60303169 D1 DE 60303169D1
Authority
DE
Germany
Prior art keywords
acrylamide
alkyl
cationic
same
transfection system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60303169T
Other languages
English (en)
Other versions
DE60303169T2 (de
Inventor
Arjen Mike Funhoff
Nostrum Cornelis Franciscu Van
Wilhelmus Everhardus Hennink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OctoPlus Technologies BV
Original Assignee
OctoPlus Technologies BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OctoPlus Technologies BV filed Critical OctoPlus Technologies BV
Application granted granted Critical
Publication of DE60303169D1 publication Critical patent/DE60303169D1/de
Publication of DE60303169T2 publication Critical patent/DE60303169T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/60—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Polymerization Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DE60303169T 2003-08-07 2003-08-07 Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System Expired - Fee Related DE60303169T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03077473A EP1505089B1 (de) 2003-08-07 2003-08-07 Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System

Publications (2)

Publication Number Publication Date
DE60303169D1 true DE60303169D1 (de) 2006-04-06
DE60303169T2 DE60303169T2 (de) 2006-08-31

Family

ID=33547691

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60303169T Expired - Fee Related DE60303169T2 (de) 2003-08-07 2003-08-07 Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System

Country Status (4)

Country Link
EP (1) EP1505089B1 (de)
AT (1) ATE315591T1 (de)
DE (1) DE60303169T2 (de)
ES (1) ES2255659T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012118966A1 (en) * 2011-03-01 2012-09-07 Lanter Andrew Container system
EP2522689A1 (de) 2011-05-13 2012-11-14 Universität Bayreuth Nicht virale Transfektionssysteme
DE102011118018B4 (de) 2011-10-25 2017-10-26 Plasmidfactory Gmbh & Co. Kg Minicircles mit Transpositionskassetten und ihre Verwendung zur Transformation von Zellen
US9834695B2 (en) 2013-10-11 2017-12-05 Hercules Llc High efficiency rheology modifers with cationic components and use thereof
DE102013220859B4 (de) 2013-10-15 2016-09-08 Plasmidfactory Gmbh & Co. Kg Minicircles mit viralen Expressionskassetten und ihre Verwendung zur Transformation von Zellen zur Erzeugung rekombinanter Viren oder viraler Genvektoren
EP3344766B8 (de) 2015-09-01 2021-03-17 Dana-Farber Cancer Institute, Inc. Systeme und verfahren zur selektion von grns targeting strängen zur cas9 lokalisation
AU2017281706B2 (en) * 2016-06-23 2021-05-13 The Regents Of The University Of Colorado, A Body Corporate Control of polymer network structures via nanogels

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0463597A (ja) * 1990-06-29 1992-02-28 W R Grace & Co 細胞への遺伝子導入法およびそれに用いる細胞固定板
ATE294875T1 (de) * 1995-10-25 2005-05-15 Octoplus B V Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen
EP1022340A1 (de) * 1999-01-21 2000-07-26 OctoPlus B.V. Stabilisierung von Zusammensetzungen die nicht-virale nukeinsäure-Transfer-Zusammensetzungen enthalten

Also Published As

Publication number Publication date
DE60303169T2 (de) 2006-08-31
ES2255659T3 (es) 2006-07-01
EP1505089B1 (de) 2006-01-11
EP1505089A1 (de) 2005-02-09
ATE315591T1 (de) 2006-02-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee