DE60237607D1 - Verwendung von magnesium zur verhinderung der in-stent thrombose und komplikationen nach gefässinterner arterioplastik mit stent einführung - Google Patents

Verwendung von magnesium zur verhinderung der in-stent thrombose und komplikationen nach gefässinterner arterioplastik mit stent einführung

Info

Publication number
DE60237607D1
DE60237607D1 DE60237607T DE60237607T DE60237607D1 DE 60237607 D1 DE60237607 D1 DE 60237607D1 DE 60237607 T DE60237607 T DE 60237607T DE 60237607 T DE60237607 T DE 60237607T DE 60237607 D1 DE60237607 D1 DE 60237607D1
Authority
DE
Germany
Prior art keywords
stent
complications
magnesium
arterioplastics
prevent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60237607T
Other languages
English (en)
Inventor
Sanjay Kaul
Prediman K Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cedars Sinai Medical Center
Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Application granted granted Critical
Publication of DE60237607D1 publication Critical patent/DE60237607D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/921—Blood vessel
DE60237607T 2001-07-18 2002-07-10 Verwendung von magnesium zur verhinderung der in-stent thrombose und komplikationen nach gefässinterner arterioplastik mit stent einführung Expired - Lifetime DE60237607D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/908,342 US6692772B2 (en) 2001-07-18 2001-07-18 Prevention of in-stent thrombosis and complications after arterial angioplasty with stent placement using magnesium
PCT/US2002/021630 WO2003007970A2 (en) 2001-07-18 2002-07-10 Use of magnesium for preventing in-stent thrombosis and complications after arterial angioplasty with stent placement

Publications (1)

Publication Number Publication Date
DE60237607D1 true DE60237607D1 (de) 2010-10-21

Family

ID=25425625

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60237607T Expired - Lifetime DE60237607D1 (de) 2001-07-18 2002-07-10 Verwendung von magnesium zur verhinderung der in-stent thrombose und komplikationen nach gefässinterner arterioplastik mit stent einführung

Country Status (8)

Country Link
US (4) US6692772B2 (de)
EP (2) EP1406697B1 (de)
JP (1) JP2005500330A (de)
AT (1) ATE480298T1 (de)
AU (2) AU2002318284B2 (de)
CA (1) CA2454043A1 (de)
DE (1) DE60237607D1 (de)
WO (1) WO2003007970A2 (de)

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US20050267560A1 (en) * 2000-02-03 2005-12-01 Cook Incorporated Implantable bioabsorbable valve support frame
US6692772B2 (en) * 2001-07-18 2004-02-17 Cedars-Sinai Medical Center Prevention of in-stent thrombosis and complications after arterial angioplasty with stent placement using magnesium
DE10361941A1 (de) * 2003-12-24 2005-07-28 Restate Patent Ag Magnesiumhaltige Beschichtung
JP2006061381A (ja) * 2004-08-26 2006-03-09 Terumo Corp 血管内インプラント
US20060252830A1 (en) * 2005-05-06 2006-11-09 Brandon Stephen F Method for the treatment of magnesium and potassium deficiencies
US20060252831A1 (en) * 2005-05-06 2006-11-09 Christopher Offen Method for the treatment of magnesium and potassium deficiencies
US20070282432A1 (en) * 2006-05-31 2007-12-06 Stinson Jonathan S Implantable medical endoprostheses
US8273402B2 (en) * 2007-02-26 2012-09-25 Medtronic Vascular, Inc. Drug coated stent with magnesium topcoat
US8142803B2 (en) * 2007-03-22 2012-03-27 Magceutics, Inc. Magnesium compositions and uses thereof for neurological disorders
US8205317B2 (en) * 2007-07-16 2012-06-26 Medtronic Vascular, Inc. Method of manufacturing a controlled porosity stent
DE102008040791A1 (de) * 2008-07-28 2010-02-04 Biotronik Vi Patent Ag Endoprothese und Verfahren zur Herstellung derselben
US8377473B2 (en) * 2009-07-01 2013-02-19 Magceutics, Inc. Slow release magnesium composition and uses thereof
EP2540293A1 (de) * 2011-06-28 2013-01-02 Biotronik AG Erhöhung der effizienz der therapeutischen Wirkung pharmakologischer Wirsktoff-freissetzender medizinischer Vorrichtungen

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US3850211A (en) * 1973-06-07 1974-11-26 M Ganier Mortise tool
CH577461A5 (de) 1975-08-13 1976-07-15 Robins Co Inc A H
US4485857A (en) * 1983-01-03 1984-12-04 Norfield Manufacturing Co. Door processing machine
US4615654A (en) * 1984-08-31 1986-10-07 Amerock Corporation Portable router
US5140012A (en) * 1990-05-31 1992-08-18 E. R. Squibb & Sons, Inc. Method for preventing onset of restenosis after angioplasty employing pravastatin
DE4237560A1 (de) * 1992-11-06 1994-05-11 Salice Arturo Spa Adapter für Bohrmaschinen
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US5843996A (en) 1996-01-25 1998-12-01 Weglicki; William B. Intravenous magnesium gluconate for treatment of conditions caused by excessive oxidative stress due to free radical distribution
WO1997037670A1 (en) 1996-04-10 1997-10-16 Chronorx, Llc Unit dosage forms, containing magnesium, vitamin c, vitamin e, folate and selenium, for treatment of vasoconstriction and related conditions
US5725036A (en) * 1996-05-23 1998-03-10 Walter; Daniel L. Plunge router with precision adjustment mechanism and conversion kit
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5762115A (en) * 1997-02-25 1998-06-09 Shouse; Gary A. Door template for use with a drill and a router
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DE59913189D1 (de) * 1998-06-25 2006-05-04 Biotronik Ag Implantierbare, bioresorbierbare Gefässwandstütze, insbesondere Koronarstent
US6207218B1 (en) * 1998-09-15 2001-03-27 Isotis B.V. Method for coating medical implants
DE19855421C2 (de) * 1998-11-02 2001-09-20 Alcove Surfaces Gmbh Implantat
US6201028B1 (en) * 1998-12-08 2001-03-13 The Rockefeller University Methods and compositions for prevention and treatment of atherosclerosis and hyperlipidemia with non-steroidal anti-inflammatory drugs
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JP2000210380A (ja) 1999-01-26 2000-08-02 Nagase & Co Ltd 血液凝固阻止剤及びそれを収納した採血容器
EP1155418B1 (de) * 1999-02-25 2007-04-11 GE Healthcare Limited Medizinische instrumente und vorrichtungen mit verbesserter ultraschall-sichtbarkeit
US6692772B2 (en) * 2001-07-18 2004-02-17 Cedars-Sinai Medical Center Prevention of in-stent thrombosis and complications after arterial angioplasty with stent placement using magnesium

Also Published As

Publication number Publication date
US6692772B2 (en) 2004-02-17
US20040138739A1 (en) 2004-07-15
CA2454043A1 (en) 2003-01-30
ATE480298T1 (de) 2010-09-15
AU2006201961A1 (en) 2006-06-01
AU2002318284B2 (en) 2006-03-16
US7279183B2 (en) 2007-10-09
US20040247642A1 (en) 2004-12-09
EP1406697B1 (de) 2010-09-08
US7452373B2 (en) 2008-11-18
EP1406697A2 (de) 2004-04-14
WO2003007970A3 (en) 2003-11-20
US20040146586A1 (en) 2004-07-29
JP2005500330A (ja) 2005-01-06
WO2003007970A2 (en) 2003-01-30
US20030017188A1 (en) 2003-01-23
EP2216030A1 (de) 2010-08-11

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