DE60236722D1 - Vorrichtung und verfahren zur photodynamischen diagnose von tumorgewebe - Google Patents

Vorrichtung und verfahren zur photodynamischen diagnose von tumorgewebe

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Publication number
DE60236722D1
DE60236722D1 DE60236722T DE60236722T DE60236722D1 DE 60236722 D1 DE60236722 D1 DE 60236722D1 DE 60236722 T DE60236722 T DE 60236722T DE 60236722 T DE60236722 T DE 60236722T DE 60236722 D1 DE60236722 D1 DE 60236722D1
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DE
Germany
Prior art keywords
camera
telescopic device
proximal end
filter
surgical telescopic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60236722T
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English (en)
Inventor
James Mcgreevy
Charles B Grissom
Michelle Cannon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah Research Foundation UURF
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University of Utah Research Foundation UURF
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Publication of DE60236722D1 publication Critical patent/DE60236722D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
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    • A61B1/00186Optical arrangements with imaging filters
    • AHUMAN NECESSITIES
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    • A61B1/043Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
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    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
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    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
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    • A61K47/551Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds one of the codrug's components being a vitamin, e.g. niacinamide, vitamin B3, cobalamin, vitamin B12, folate, vitamin A or retinoic acid
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    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
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    • A61K49/0013Luminescence
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    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
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    • A61K49/0043Fluorescein, used in vivo
    • AHUMAN NECESSITIES
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    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052Small organic molecules
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    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/0012Surgical microscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0646Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements with illumination filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B1/313Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
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    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
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    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
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    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/64Fluorescence; Phosphorescence
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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DE60236722T 2001-03-16 2002-03-15 Vorrichtung und verfahren zur photodynamischen diagnose von tumorgewebe Expired - Lifetime DE60236722D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27603601P 2001-03-16 2001-03-16
US33631601P 2001-10-30 2001-10-30
PCT/US2002/007699 WO2002074339A1 (en) 2001-03-16 2002-03-15 Deveice and method for the photodynamic diagnosis of tumor tissue

Publications (1)

Publication Number Publication Date
DE60236722D1 true DE60236722D1 (de) 2010-07-29

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DE60236722T Expired - Lifetime DE60236722D1 (de) 2001-03-16 2002-03-15 Vorrichtung und verfahren zur photodynamischen diagnose von tumorgewebe

Country Status (7)

Country Link
EP (1) EP1370291B1 (de)
JP (1) JP2004525697A (de)
AT (1) ATE471157T1 (de)
CA (2) CA2441107C (de)
DE (1) DE60236722D1 (de)
NZ (1) NZ528920A (de)
WO (1) WO2002074339A1 (de)

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SE527164C2 (sv) 2003-05-14 2006-01-10 Spectracure Ab Anordning och metod för terapi och diagnostik innefattande optiska komponenter för distribution av strålning
JP4663258B2 (ja) * 2003-06-17 2011-04-06 オリンパス株式会社 内視鏡装置
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DE102007010046A1 (de) * 2007-03-01 2008-09-04 Siemens Ag PCa-Nachweisgerät
US8883723B2 (en) 2007-03-05 2014-11-11 Syracuse University Conjugate of insulin and vitamin B12 for oral delivery
CN101109699B (zh) * 2007-07-28 2010-09-15 中国科学院安徽光学精密机械研究所 大气成分垂直分布探测的多轴差分吸收光谱方法与装置
CN101609207B (zh) * 2009-07-17 2011-01-05 清华大学 可留置的荧光显微内窥成像系统及成像方法
EP2514357B1 (de) * 2011-04-18 2014-10-29 Karl Storz GmbH & Co. KG Exoskop
JP5889398B2 (ja) * 2012-04-05 2016-03-22 Sbiファーマ株式会社 センチネルリンパ節がん転移識別装置
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CA2441107A1 (en) 2002-09-26
JP2004525697A (ja) 2004-08-26
ATE471157T1 (de) 2010-07-15
EP1370291B1 (de) 2010-06-16
CA2441107C (en) 2012-06-05
EP1370291A1 (de) 2003-12-17
CA2771039A1 (en) 2002-09-26

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