DE60235875D1 - Herstellungsverfahren zur kontrolle der teilchengrösse von albumin macroaggregaten - Google Patents

Herstellungsverfahren zur kontrolle der teilchengrösse von albumin macroaggregaten

Info

Publication number
DE60235875D1
DE60235875D1 DE60235875T DE60235875T DE60235875D1 DE 60235875 D1 DE60235875 D1 DE 60235875D1 DE 60235875 T DE60235875 T DE 60235875T DE 60235875 T DE60235875 T DE 60235875T DE 60235875 D1 DE60235875 D1 DE 60235875D1
Authority
DE
Germany
Prior art keywords
serum albumin
reaction mixture
albumine
manufacturing
particle size
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235875T
Other languages
English (en)
Inventor
Ernst Schramm
Rama K Narra
Bruce Kuczynski
Julius P Zodda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Diagnostics Inc
Original Assignee
Bracco Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Diagnostics Inc filed Critical Bracco Diagnostics Inc
Application granted granted Critical
Publication of DE60235875D1 publication Critical patent/DE60235875D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1255—Granulates, agglomerates, microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicinal Preparation (AREA)
DE60235875T 2001-02-28 2002-02-27 Herstellungsverfahren zur kontrolle der teilchengrösse von albumin macroaggregaten Expired - Lifetime DE60235875D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/795,272 US6730286B2 (en) 2001-02-28 2001-02-28 Manufacturing process to control particle size
PCT/US2002/006023 WO2002067997A1 (en) 2001-02-28 2002-02-27 Manufacturing process to control particle size

Publications (1)

Publication Number Publication Date
DE60235875D1 true DE60235875D1 (de) 2010-05-20

Family

ID=25165150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235875T Expired - Lifetime DE60235875D1 (de) 2001-02-28 2002-02-27 Herstellungsverfahren zur kontrolle der teilchengrösse von albumin macroaggregaten

Country Status (7)

Country Link
US (1) US6730286B2 (de)
EP (1) EP1370300B1 (de)
JP (1) JP2004521920A (de)
AT (1) ATE463262T1 (de)
CA (1) CA2438902C (de)
DE (1) DE60235875D1 (de)
WO (1) WO2002067997A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005318697A1 (en) * 2004-12-22 2006-06-29 Novozymes A/S Recombinant production of serum albumin
WO2006119280A2 (en) * 2005-05-03 2006-11-09 Handylab, Inc. Lyophilized pellets
EP2471557A1 (de) 2010-12-27 2012-07-04 Università degli Studi di Genova Konjugat von Humanalbumin und 2-(4-Isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecan-1,4,7,10-tetraessigsäure zur Lokalisierung von Radionukliden zu diagnostischen und therapeutischen Zwecken

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674900A (en) 1967-01-03 1972-07-04 Lloyd M Thompson Radioactive macroaggregates of serum albumin
US3758678A (en) * 1968-09-26 1973-09-11 Minnesota Mining & Mfg Biodegradable radioactive polysaccharide particles
FR2088139B1 (de) * 1970-05-22 1973-06-08 Philips France
US3862299A (en) 1970-09-23 1975-01-21 Squibb & Sons Inc Technetium-99m albumin aggregates
BE786566A (fr) 1971-07-20 1973-01-22 Squibb & Sons Inc Agregats a base de tc-99m et d'albumine
US3863004A (en) 1972-03-20 1975-01-28 Mallinckrodt Chemical Works Denatured macroprotein with divalent tin for tagging with technetium-99m and method of preparation
US3875299A (en) * 1972-05-05 1975-04-01 Medi Physics Inc Technetium labeled tin colloid radiopharmaceuticals
US4024233A (en) 1972-06-05 1977-05-17 Medi-Physics, Inc. 99M-technetium labeled macroaggregated human serum albumin pharmaceutical
US4042677A (en) * 1974-08-29 1977-08-16 Union Carbide Corporation Technetium-99m labeled radiodiagnostic agents and method of preparation
US3987157A (en) 1974-08-29 1976-10-19 Union Carbide Corporation Technetium 99-m labeled radio-diagnostic agents employing stannous tartrate and method of preparation
FR2288477A1 (fr) 1974-10-22 1976-05-21 Manche Union Coop Agr Laiti Procede de production d'acide sialique et de glycoproteines a partir de lactoserum de fromagerie
US4094965A (en) 1977-04-01 1978-06-13 New England Nuclear Corporation Diagnostic agents containing albumin and method for making same
US4187285A (en) 1977-12-16 1980-02-05 E. R. Squibb & Sons, Inc. Microaggregated albumin
CA1112162A (en) * 1978-04-20 1981-11-10 Eugene L. Saklad Albumin microaggregates for radioactive scanning of reticuloendothelial systems
JPS5659716A (en) 1979-10-22 1981-05-23 Toyo Soda Mfg Co Ltd Separating method of gamma-globulin aggregate with membrane
CH652599A5 (de) * 1981-08-28 1985-11-29 Solco Basel Ag Verfahren zur herstellung physiologisch abbaubarer kolloidaler, human-serumalbumin enthaltender produkte und ihre verwendung.
US5096696A (en) * 1990-02-05 1992-03-17 The Research Foundation Of State University Of New York Binding of radiolabeled albumin fragments to fibrin clots
US5232828A (en) * 1992-03-09 1993-08-03 Becton, Dickinson And Company Coating agents for cell recovery
US5521287A (en) 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
US5589189A (en) * 1994-09-14 1996-12-31 Nexstar Pharmaceuticals, Inc. Liposome dispersion

Also Published As

Publication number Publication date
WO2002067997A1 (en) 2002-09-06
EP1370300A1 (de) 2003-12-17
JP2004521920A (ja) 2004-07-22
CA2438902C (en) 2010-01-05
EP1370300A4 (de) 2008-03-05
US6730286B2 (en) 2004-05-04
ATE463262T1 (de) 2010-04-15
CA2438902A1 (en) 2002-09-06
US20020182148A1 (en) 2002-12-05
EP1370300B1 (de) 2010-04-07

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Legal Events

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