DE60234467D1 - Molekulare eigenschaften von nichtkleinzelligem lungenkrebs - Google Patents
Molekulare eigenschaften von nichtkleinzelligem lungenkrebsInfo
- Publication number
- DE60234467D1 DE60234467D1 DE60234467T DE60234467T DE60234467D1 DE 60234467 D1 DE60234467 D1 DE 60234467D1 DE 60234467 T DE60234467 T DE 60234467T DE 60234467 T DE60234467 T DE 60234467T DE 60234467 D1 DE60234467 D1 DE 60234467D1
- Authority
- DE
- Germany
- Prior art keywords
- sage
- small cell
- gene expression
- lung cancer
- cell lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31240001P | 2001-08-16 | 2001-08-16 | |
PCT/US2002/026027 WO2003015613A2 (en) | 2001-08-16 | 2002-08-16 | Molecular characteristics of non-small cell lung cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60234467D1 true DE60234467D1 (de) | 2009-12-31 |
Family
ID=23211260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60234467T Expired - Lifetime DE60234467D1 (de) | 2001-08-16 | 2002-08-16 | Molekulare eigenschaften von nichtkleinzelligem lungenkrebs |
Country Status (8)
Country | Link |
---|---|
US (2) | US7332590B2 (de) |
EP (1) | EP1453977B1 (de) |
JP (1) | JP2005503145A (de) |
AT (1) | ATE449187T1 (de) |
AU (1) | AU2002355963A1 (de) |
CA (1) | CA2456334A1 (de) |
DE (1) | DE60234467D1 (de) |
WO (1) | WO2003015613A2 (de) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003015613A2 (en) * | 2001-08-16 | 2003-02-27 | The United States Of America As Represented By The Secretrary Of Health And Human Services | Molecular characteristics of non-small cell lung cancer |
ATE331044T1 (de) * | 2003-03-04 | 2006-07-15 | Pamgene Bv | Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren |
GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
BRPI0410634A (pt) * | 2003-05-30 | 2006-06-13 | Astrazeneca Uk Ltd | processo |
CA3084542A1 (en) * | 2003-06-10 | 2005-01-06 | The Trustees Of Boston University | Gene expression analysis of airway epithelial cells for diagnosing lung cancer |
US20060003391A1 (en) * | 2003-08-11 | 2006-01-05 | Ring Brian Z | Reagents and methods for use in cancer diagnosis, classification and therapy |
WO2005032495A2 (en) * | 2003-10-03 | 2005-04-14 | Bayer Pharmaceuticals Corporation | Gene expression profiles and methods of use |
JP4938451B2 (ja) | 2004-03-23 | 2012-05-23 | オンコセラピー・サイエンス株式会社 | 非小細胞肺癌の診断のための方法 |
US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
WO2006056080A1 (en) * | 2004-11-29 | 2006-06-01 | Diagnocure Inc. | Gpx2 a specific and sensitive target for lung cancer diagnosis, prognosis and/or theranosis |
US20100035244A1 (en) | 2005-04-14 | 2010-02-11 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
US7504225B2 (en) | 2005-05-12 | 2009-03-17 | Applied Genomics, Inc. | Reagents and methods for use in cancer diagnosis, classification and therapy |
KR100710462B1 (ko) | 2005-08-24 | 2007-04-24 | 광주과학기술원 | 폐암 진단용 퍼옥시레독신-i자가항체 마커 및 이를 이용한진단키트 |
US20100137163A1 (en) | 2006-01-11 | 2010-06-03 | Link Darren R | Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors |
EP1999472A2 (de) | 2006-03-09 | 2008-12-10 | The Trustees Of Boston University | Diagnose- und prognoseverfahren für lungenerkrankungen mittels genexpressionsprofilen aus nasenepithelzellen |
US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
WO2007133710A2 (en) | 2006-05-11 | 2007-11-22 | Raindance Technologies, Inc. | Microfluidic devices and methods of use thereof |
WO2008021123A1 (en) | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
EA010352B1 (ru) * | 2006-10-09 | 2008-08-29 | Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) | Способ дифференциального анализа протеомов |
US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
CN101990577A (zh) | 2007-09-19 | 2011-03-23 | 波士顿大学理事会 | 鉴定肺病药物开发的新途径 |
JP5583117B2 (ja) * | 2008-05-14 | 2014-09-03 | ユニバーシティー ヘルス ネットワーク | 非小細胞肺癌およびアジュバント化学療法に関する予後診断的および予測的な遺伝子シグネチャー |
EP2145964A1 (de) * | 2008-07-17 | 2010-01-20 | Universität Zu Köln | Verfahren zur Früherkennung und Prognose von Lungenkrebs |
EP2315629B1 (de) | 2008-07-18 | 2021-12-15 | Bio-Rad Laboratories, Inc. | Tröpfchenbibliotheken |
US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
JP2012519290A (ja) | 2009-03-04 | 2012-08-23 | エフ.ホフマン−ラ ロシュ アーゲー | 肺の扁平上皮癌のためのマーカーとしてのセルピンb13 |
EP2411148B1 (de) | 2009-03-23 | 2018-02-21 | Raindance Technologies, Inc. | Manipulation von mikrofluidiktröpfchen |
EP2486409A1 (de) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Markiertes nanomaterial auf siliziumbasis mit verbesserten eigenschaften und seine verwendung |
EP2493916B1 (de) * | 2009-10-26 | 2016-06-08 | Externautics S.p.A. | Marker für lungentumore und deren verwendung |
EP2498778A1 (de) | 2009-11-13 | 2012-09-19 | The United States Of America, As Represented By The Secretary, Department of Health and Human Services | Diazeniumdiolatverbindungen, pharmazeutische zusammensetzungen und verfahren zur behandlung von krebs |
US10837883B2 (en) | 2009-12-23 | 2020-11-17 | Bio-Rad Laboratories, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
US8535889B2 (en) | 2010-02-12 | 2013-09-17 | Raindance Technologies, Inc. | Digital analyte analysis |
US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
EP3447155A1 (de) | 2010-09-30 | 2019-02-27 | Raindance Technologies, Inc. | Sandwichassays in tröpfchen |
EP3859011A1 (de) | 2011-02-11 | 2021-08-04 | Bio-Rad Laboratories, Inc. | Verfahren zur bildung gemischter tröpfchen |
WO2012112804A1 (en) | 2011-02-18 | 2012-08-23 | Raindance Technoligies, Inc. | Compositions and methods for molecular labeling |
US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
EP3216872B1 (de) | 2011-06-02 | 2020-04-01 | Bio-Rad Laboratories, Inc. | Enzymquantifizierung |
US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
WO2013120089A1 (en) | 2012-02-10 | 2013-08-15 | Raindance Technologies, Inc. | Molecular diagnostic screening assay |
WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
EP3626308A1 (de) | 2013-03-14 | 2020-03-25 | Veracyte, Inc. | Verfahren zur bewertung eines copd-status |
US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
EP2986762B1 (de) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digitale analyse von analyten |
US20150087728A1 (en) * | 2013-09-20 | 2015-03-26 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
US9594085B2 (en) | 2014-02-03 | 2017-03-14 | Integrated Diagnostics, Inc. | Integrated quantification method for protein measurements in clinical proteomics |
WO2016073768A1 (en) | 2014-11-05 | 2016-05-12 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
CN105154542B (zh) * | 2015-09-01 | 2018-04-17 | 杭州源清生物科技有限公司 | 一组用于肺癌分子分型的基因及其应用 |
US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
US10927417B2 (en) | 2016-07-08 | 2021-02-23 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
JP2022527972A (ja) * | 2019-04-02 | 2022-06-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 前悪性病変を有する患者において癌を予測及び予防する方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4445990A (en) * | 1981-11-12 | 1984-05-01 | General Electric Company | Electrolytic reactor for cleaning wastewater |
US5763165A (en) * | 1994-03-10 | 1998-06-09 | Ludwig Institute For Cancer Research | Method for determining lung adenocarcinomas by assaying for one or more of MAGE-1, MAGE-2 and MAGE-3 |
US6087102A (en) * | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
CA2323833A1 (en) * | 1998-03-31 | 1999-10-07 | Genzyme Corporation | Compositions and methods for the identification of lung tumor cells |
EP1082459A4 (de) | 1998-05-21 | 2002-09-25 | Diadexus Inc | Neue methode zur diagnose, überwachung und bestimmung des stadiums von lungenkrebs |
US20030065157A1 (en) * | 2001-04-04 | 2003-04-03 | Lasek Amy W. | Genes expressed in lung cancer |
WO2003015613A2 (en) * | 2001-08-16 | 2003-02-27 | The United States Of America As Represented By The Secretrary Of Health And Human Services | Molecular characteristics of non-small cell lung cancer |
US20060151337A1 (en) * | 2005-01-07 | 2006-07-13 | Gilmore F W | Electrocoagulation Reaction Chamber |
-
2002
- 2002-08-16 WO PCT/US2002/026027 patent/WO2003015613A2/en active Application Filing
- 2002-08-16 CA CA002456334A patent/CA2456334A1/en not_active Abandoned
- 2002-08-16 US US10/486,844 patent/US7332590B2/en not_active Expired - Fee Related
- 2002-08-16 DE DE60234467T patent/DE60234467D1/de not_active Expired - Lifetime
- 2002-08-16 JP JP2003520378A patent/JP2005503145A/ja active Pending
- 2002-08-16 AU AU2002355963A patent/AU2002355963A1/en not_active Abandoned
- 2002-08-16 AT AT02794901T patent/ATE449187T1/de not_active IP Right Cessation
- 2002-08-16 EP EP02794901A patent/EP1453977B1/de not_active Expired - Lifetime
-
2007
- 2007-07-27 US US11/829,483 patent/US7709202B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2456334A1 (en) | 2003-02-27 |
EP1453977A2 (de) | 2004-09-08 |
EP1453977B1 (de) | 2009-11-18 |
US20090270265A1 (en) | 2009-10-29 |
US20050136403A1 (en) | 2005-06-23 |
JP2005503145A (ja) | 2005-02-03 |
US7332590B2 (en) | 2008-02-19 |
WO2003015613A3 (en) | 2004-06-24 |
WO2003015613A2 (en) | 2003-02-27 |
ATE449187T1 (de) | 2009-12-15 |
EP1453977A4 (de) | 2005-04-20 |
AU2002355963A1 (en) | 2003-03-03 |
US7709202B2 (en) | 2010-05-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R082 | Change of representative |
Ref document number: 1453977 Country of ref document: EP Representative=s name: WINTER, BRANDL, FUERNISS, HUEBNER, ROESS, KAIS, DE |