DE60231428D1 - Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff - Google Patents
Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoffInfo
- Publication number
- DE60231428D1 DE60231428D1 DE60231428T DE60231428T DE60231428D1 DE 60231428 D1 DE60231428 D1 DE 60231428D1 DE 60231428 T DE60231428 T DE 60231428T DE 60231428 T DE60231428 T DE 60231428T DE 60231428 D1 DE60231428 D1 DE 60231428D1
- Authority
- DE
- Germany
- Prior art keywords
- polyethylene glycol
- aerosol compositions
- functionalized polyethylene
- medical aerosol
- glycol agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34278701P | 2001-12-21 | 2001-12-21 | |
| PCT/US2002/041299 WO2003059317A2 (en) | 2001-12-21 | 2002-12-20 | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60231428D1 true DE60231428D1 (de) | 2009-04-16 |
Family
ID=23343270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60231428T Expired - Lifetime DE60231428D1 (de) | 2001-12-21 | 2002-12-20 | Medizinische aerosolzusammensetzungen mit einem funktionalisierten polyethylenglykol-hilfsstoff |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7718162B2 (https=) |
| EP (1) | EP1458357B1 (https=) |
| JP (1) | JP4959919B2 (https=) |
| AT (1) | ATE424186T1 (https=) |
| AU (1) | AU2002367032B8 (https=) |
| CA (1) | CA2470520A1 (https=) |
| DE (1) | DE60231428D1 (https=) |
| WO (1) | WO2003059317A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2470520A1 (en) | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
| JP2005514440A (ja) * | 2001-12-21 | 2005-05-19 | スリーエム イノベイティブ プロパティズ カンパニー | アミドおよび／またはエステルを含有する、賦形剤化合物を含む、医用エアロゾル組成物 |
| JP2005514437A (ja) * | 2001-12-21 | 2005-05-19 | スリーエム イノベイティブ プロパティズ カンパニー | イオン対複合体を含む医薬用エアロゾル製剤 |
| GB0614621D0 (en) | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
| GB0620700D0 (en) | 2006-10-19 | 2006-11-29 | 3M Innovative Properties Co | Metered dose valves and dispensers |
| DK2480197T3 (en) | 2009-09-25 | 2016-01-25 | Reddys Lab Ltd Dr | Compositions containing triptanforbindelser |
| US11337962B2 (en) | 2009-09-25 | 2022-05-24 | Upsher-Smith Laboratories, Llc | Formulations comprising triptan compounds |
| EP3020393B1 (en) | 2009-12-16 | 2020-10-07 | 3M Innovative Properties Company | Formulations and methods for controlling mdi particle size delivery |
| GB201118188D0 (en) | 2011-10-21 | 2011-12-07 | 3M Innovative Properties Co | Manufacture of medicinal aerosol canisters |
| GB201210580D0 (en) | 2012-06-14 | 2012-08-01 | 3M Innovative Properties Co | Metered dose dispensing valve |
| GB201221063D0 (en) | 2012-11-23 | 2013-01-09 | 3M Innovative Properties Co | Metered dose dispensing valve |
| US11981619B2 (en) | 2017-07-07 | 2024-05-14 | Basf Se | Alkoxylated esteramines and salts thereof |
| JP7657496B2 (ja) * | 2021-12-02 | 2025-04-07 | レジェロン，インコーポレイテッド | 多機能用途を有する天然賦形剤およびその調製プロセス |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1163028B (de) * | 1960-03-09 | 1964-02-13 | Hoechst Ag | Verfahren zur Polymerisation von Vinylchlorid |
| JPS63503304A (ja) | 1986-03-10 | 1988-12-02 | ブルグハルト，クルト | 医薬製剤およびその製造方法 |
| AU601176B2 (en) | 1986-03-10 | 1990-09-06 | Kurt Burghart | Benzodiazepine aerosols |
| US5225183A (en) | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5342940A (en) * | 1989-05-27 | 1994-08-30 | Sumitomo Pharmaceuticals Company, Limited | Polyethylene glycol derivatives, process for preparing the same |
| WO1992000061A1 (en) | 1990-06-29 | 1992-01-09 | Fisons Plc | Pressurised aerosol compositions |
| AU5171293A (en) | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
| ATE177941T1 (de) | 1992-12-09 | 1999-04-15 | Boehringer Ingelheim Pharma | Stabilisierte medizinische aerosollösungen |
| ES2122261T3 (es) | 1993-03-17 | 1998-12-16 | Minnesota Mining & Mfg | Formulacion de aerosol que contiene un adyuvante de dispersion derivado de un ester, una amida o un mercaptoester. |
| ES2107203T3 (es) | 1993-03-17 | 1997-11-16 | Minnesota Mining & Mfg | Una formulacion de aerosol que contiene un adyuvante de dispersion derivado de un diol-diacido. |
| US5492688A (en) | 1993-04-28 | 1996-02-20 | The Center For Innovative Technology | Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable suspending, solubilizing, wetting, emulsifying or lubricating agent |
| JPH09506097A (ja) | 1993-12-02 | 1997-06-17 | アボツト・ラボラトリーズ | 非ｃｆｃ噴射剤と共に用いるエアロゾル薬物調剤 |
| US5508023A (en) * | 1994-04-11 | 1996-04-16 | The Center For Innovative Technology | Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant |
| US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| ZA9711732B (en) * | 1996-12-31 | 1998-12-28 | Quadrant Holdings Cambridge | Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery |
| US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| US6218353B1 (en) | 1997-08-27 | 2001-04-17 | Micell Technologies, Inc. | Solid particulate propellant systems and aerosol containers employing the same |
| US6136294C1 (en) | 1998-09-22 | 2002-09-24 | Aeropharm Technology Inc | Amino acid stabilized medical aerosol formulation |
| BR9914799A (pt) | 1998-10-27 | 2001-07-10 | Alcon Lab Inc | Sistema conservante para composições farmacêuticas administráveis topicamente contendo um sabão de ácido graxo/aminoácido |
| US6258857B1 (en) | 1999-02-04 | 2001-07-10 | Kyowa Industrial Co., Ltd. | Internal liquid composition contained as internal liquid in a releasing container and releasing container product |
| GB0016876D0 (en) | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Novel formulation |
| US7217409B2 (en) | 2000-09-22 | 2007-05-15 | Smithkline Beecham Corporation | Alkanoic acid derivatives |
| CZ20033182A3 (cs) | 2001-05-21 | 2004-09-15 | Nektar Therapeutics | Inzulínový prostředek a způsob podávání inzulínu |
| GB0125127D0 (en) | 2001-10-19 | 2001-12-12 | Glaxo Group Ltd | Compounds |
| JP2005514440A (ja) | 2001-12-21 | 2005-05-19 | スリーエム イノベイティブ プロパティズ カンパニー | アミドおよび／またはエステルを含有する、賦形剤化合物を含む、医用エアロゾル組成物 |
| CA2470520A1 (en) | 2001-12-21 | 2003-07-24 | 3M Innovative Properties Company | Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient |
-
2002
- 2002-12-20 CA CA002470520A patent/CA2470520A1/en not_active Abandoned
- 2002-12-20 EP EP02806511A patent/EP1458357B1/en not_active Expired - Lifetime
- 2002-12-20 AU AU2002367032A patent/AU2002367032B8/en not_active Ceased
- 2002-12-20 DE DE60231428T patent/DE60231428D1/de not_active Expired - Lifetime
- 2002-12-20 JP JP2003559480A patent/JP4959919B2/ja not_active Expired - Fee Related
- 2002-12-20 WO PCT/US2002/041299 patent/WO2003059317A2/en not_active Ceased
- 2002-12-20 AT AT02806511T patent/ATE424186T1/de not_active IP Right Cessation
- 2002-12-20 US US10/327,200 patent/US7718162B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006502086A (ja) | 2006-01-19 |
| JP4959919B2 (ja) | 2012-06-27 |
| EP1458357A2 (en) | 2004-09-22 |
| AU2002367032B2 (en) | 2008-09-25 |
| AU2002367032B8 (en) | 2008-10-23 |
| WO2003059317A2 (en) | 2003-07-24 |
| ATE424186T1 (de) | 2009-03-15 |
| AU2002367032A1 (en) | 2003-07-30 |
| US7718162B2 (en) | 2010-05-18 |
| EP1458357B1 (en) | 2009-03-04 |
| CA2470520A1 (en) | 2003-07-24 |
| WO2003059317A3 (en) | 2003-11-20 |
| US20030152521A1 (en) | 2003-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |