DE60226327T2 - Reinigungsverfahren zur grossmassstabigen produktion von gc-globulin, damit erhaltenes produkt und dessen verwendung in medizin - Google Patents

Reinigungsverfahren zur grossmassstabigen produktion von gc-globulin, damit erhaltenes produkt und dessen verwendung in medizin Download PDF

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Publication number
DE60226327T2
DE60226327T2 DE60226327T DE60226327T DE60226327T2 DE 60226327 T2 DE60226327 T2 DE 60226327T2 DE 60226327 T DE60226327 T DE 60226327T DE 60226327 T DE60226327 T DE 60226327T DE 60226327 T2 DE60226327 T2 DE 60226327T2
Authority
DE
Germany
Prior art keywords
globulin
exchange chromatography
anion exchange
virus
diafiltration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60226327T
Other languages
German (de)
English (en)
Other versions
DE60226327D1 (de
Inventor
Charlotte Svaerke Jorgensen
Inga Laursen
Gunnar Houen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut
Original Assignee
Statens Serum Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Statens Serum Institut filed Critical Statens Serum Institut
Application granted granted Critical
Publication of DE60226327D1 publication Critical patent/DE60226327D1/de
Publication of DE60226327T2 publication Critical patent/DE60226327T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE60226327T 2001-08-14 2002-08-12 Reinigungsverfahren zur grossmassstabigen produktion von gc-globulin, damit erhaltenes produkt und dessen verwendung in medizin Expired - Fee Related DE60226327T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101217 2001-08-14
DK200101217 2001-08-14
PCT/DK2002/000531 WO2003016348A2 (en) 2001-08-14 2002-08-12 A purification process for large scale production of gc-globulin, product obtained thereby and their use in medicine

Publications (2)

Publication Number Publication Date
DE60226327D1 DE60226327D1 (de) 2008-06-12
DE60226327T2 true DE60226327T2 (de) 2009-07-09

Family

ID=8160667

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60226327T Expired - Fee Related DE60226327T2 (de) 2001-08-14 2002-08-12 Reinigungsverfahren zur grossmassstabigen produktion von gc-globulin, damit erhaltenes produkt und dessen verwendung in medizin

Country Status (9)

Country Link
EP (1) EP1419177B1 (enExample)
JP (1) JP2005508892A (enExample)
AT (1) ATE393780T1 (enExample)
AU (1) AU2002321012B2 (enExample)
CA (1) CA2456843A1 (enExample)
DE (1) DE60226327T2 (enExample)
DK (1) DK1419177T3 (enExample)
ES (1) ES2305272T3 (enExample)
WO (1) WO2003016348A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1778301A2 (en) * 2004-06-29 2007-05-02 Reliance Life Sciences Pvt., Ltd. Process for improvement of virus-safe biological fluids
CN100354301C (zh) * 2005-10-13 2007-12-12 南京工业大学 化学合成多肽的新型大规模分离制备技术
US8129139B2 (en) 2009-07-13 2012-03-06 Allergan, Inc. Process for obtaining botulinum neurotoxin
SG10201503899SA (en) * 2010-05-18 2015-06-29 Abbvie Inc Apparatus And Process Of Purification Of Proteins
JP5860401B2 (ja) 2010-09-03 2016-02-16 森田薬品工業株式会社 新規Ｇｃグロブリンガラクトース脱糖体の製造方法
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
PL3081221T3 (pl) 2013-12-13 2021-12-27 Saisei Pharma Co., Ltd. Kompozycja farmaceutyczna zawierająca produkt obróbki enzymatycznej siary bydlęcej
CN111632167B (zh) * 2014-04-15 2021-12-28 勃林格殷格翰国际公司 在制造生物制品期间连续灭活病毒的方法、装置和系统
PL3290043T3 (pl) * 2015-06-01 2023-07-03 Saisei Pharma Co., Ltd. Produkt mleczny poddany obróbce enzymatycznej, sposób jego wytwarzania, kompozycja i produkt

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177002A (en) * 1989-11-20 1993-01-05 Nobuto Yamamoto In vitro enzymatic conversion of glycosylated human vitamin D binding protein to a potent macrophage activating factor
ES2124702T3 (es) * 1990-04-11 1999-02-16 Brigham & Womens Hospital Usos terapeuticos de compuestos que se unen a actina.
US6268478B1 (en) * 1996-02-12 2001-07-31 Cedars-Sinai Medical Center Intracellular vitamin D binding protein

Also Published As

Publication number Publication date
WO2003016348A3 (en) 2004-03-04
ES2305272T3 (es) 2008-11-01
EP1419177B1 (en) 2008-04-30
EP1419177A2 (en) 2004-05-19
DE60226327D1 (de) 2008-06-12
DK1419177T3 (da) 2008-08-25
JP2005508892A (ja) 2005-04-07
WO2003016348A2 (en) 2003-02-27
CA2456843A1 (en) 2003-02-27
ATE393780T1 (de) 2008-05-15
AU2002321012B2 (en) 2008-07-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee