DE60225844D1 - Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator - Google Patents

Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator

Info

Publication number
DE60225844D1
DE60225844D1 DE60225844T DE60225844T DE60225844D1 DE 60225844 D1 DE60225844 D1 DE 60225844D1 DE 60225844 T DE60225844 T DE 60225844T DE 60225844 T DE60225844 T DE 60225844T DE 60225844 D1 DE60225844 D1 DE 60225844D1
Authority
DE
Germany
Prior art keywords
photosensibilizer
phospholipides
compositions contain
micelle compositions
contain pegylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60225844T
Other languages
English (en)
Other versions
DE60225844T2 (de
Inventor
Theresa Mary Allen
Ronald Erwin Boch
Anthony S K Boey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
Novelion Therapeutics Inc
Original Assignee
University of Alberta
QLT Inc
Quadra Logic Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Alberta, QLT Inc, Quadra Logic Technologies Inc filed Critical University of Alberta
Publication of DE60225844D1 publication Critical patent/DE60225844D1/de
Application granted granted Critical
Publication of DE60225844T2 publication Critical patent/DE60225844T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
DE60225844T 2001-11-02 2002-11-01 Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator Expired - Lifetime DE60225844T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33788401P 2001-11-02 2001-11-02
US337884P 2001-11-02
PCT/CA2002/001690 WO2003037295A2 (en) 2001-11-02 2002-11-01 Micelle compositions containing pegylated phospholipids and a photosensitizer

Publications (2)

Publication Number Publication Date
DE60225844D1 true DE60225844D1 (de) 2008-05-08
DE60225844T2 DE60225844T2 (de) 2009-04-09

Family

ID=23322426

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60225844T Expired - Lifetime DE60225844T2 (de) 2001-11-02 2002-11-01 Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator

Country Status (8)

Country Link
US (1) US20040013717A1 (de)
EP (1) EP1465590B1 (de)
AT (1) ATE390121T1 (de)
AU (1) AU2002336867A1 (de)
CA (1) CA2466103C (de)
DE (1) DE60225844T2 (de)
ES (1) ES2306785T3 (de)
WO (1) WO2003037295A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005351A1 (en) * 2002-03-29 2004-01-08 Kwon Glen S. Polymeric micelle formulations of hydrophobic compounds and methods
US20040116360A1 (en) * 2002-10-15 2004-06-17 Kwon Glen S. Encapsulation and deaggregation of polyene antibiotics using poly(ethylene glycol)-phospholipid micelles
CN101861143B (zh) * 2007-11-15 2015-09-09 拜莱泰克制药市场有限公司 用于炎性疾病的光动力治疗的聚乙二醇化脂质体制剂
US20100255080A1 (en) * 2009-04-02 2010-10-07 Sesvalia Usa, Llc Liposomal ALA pharmaceutical and cosmeceutical compositions and methods of treatment
BR112014007033A2 (pt) * 2011-09-22 2017-04-11 3M Innovative Properties Co componentes termicamente isolados para uso com sistema de exaustão
US20140377180A1 (en) * 2013-06-24 2014-12-25 Canon Kabushiki Kaisha Photoacoustic contrast agent having lipid particle containing silicon naphthalocyanine analog
KR101554564B1 (ko) 2013-11-22 2015-09-21 한국과학기술원 암 질환의 진단 또는 치료용 마이셀 구조의 나노 제제 및 이의 제조방법
HUE047912T2 (hu) 2013-12-27 2020-05-28 Bilix Co Ltd Bilirubin részecskék és elõállításuk terápia során történõ alkalmazásra
EP3509569A1 (de) 2016-09-07 2019-07-17 Cadila Healthcare Limited Injizierbare sterile zusammensetzungen mit wirkstoffmizellen

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
US4837028A (en) * 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5095030A (en) * 1987-01-20 1992-03-10 University Of British Columbia Wavelength-specific cytotoxic agents
US4920143A (en) * 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US4883790A (en) * 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US5527528A (en) * 1989-10-20 1996-06-18 Sequus Pharmaceuticals, Inc. Solid-tumor treatment method
US5620689A (en) * 1989-10-20 1997-04-15 Sequus Pharmaceuuticals, Inc. Liposomes for treatment of B-cell and T-cell disorders
CA2087902C (en) * 1992-02-05 2006-10-17 Narendra Raghunathji Desai Liposome compositions of porphyrin photosensitizers
GB9502065D0 (en) * 1995-02-02 1995-03-22 Nycomed Imaging As Contrast media
US5707608A (en) * 1995-08-02 1998-01-13 Qlt Phototherapeutics, Inc. Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer
US6375930B2 (en) * 1996-06-04 2002-04-23 Board Of Regents, The University Of Texas System Membrane incorporation of texaphyrins
CZ299790B6 (cs) * 1996-08-22 2008-11-26 Skyepharma Canada Inc. Kompozice mikrocástic ve vode nerozpustné látky, farmaceutická kompozice, zpusob prípravy stabilních cástic, mikrocástice ve vode nerozpustné nebo slabe rozpustné slouceniny, kompozice obsahující tyto mikrocástice a zpusob prípravy mikrocástic
US6043237A (en) * 1996-12-10 2000-03-28 Qlt Phototherapeutics, Inc. Use of photodynamic therapy for prevention of secondary cataracts
CN1120166C (zh) * 1997-05-07 2003-09-03 不列颠哥伦比亚省大学 新一类的苯并卟啉光活性化合物
IL132066A (en) * 1997-05-07 2008-06-05 Quadra Logic Tech Inc History of monohydrobenzoporphyrin-bite (ethylene glycol) tetraalkyl esters as light-acting agents
US20050025819A1 (en) * 1997-07-14 2005-02-03 Hayat Onyuksel Materials and methods for making improved micelle compositions
EP1206288B1 (de) * 1999-08-02 2007-01-10 The Regents Of The University Of Michigan Zielgerichtete fiberlose radiative effektoren
DE60109745T2 (de) * 2000-01-26 2006-02-23 Japan Science And Technology Agency, Kawaguchi Polymere micellenartige struktur
EP1274399B1 (de) * 2000-01-28 2005-04-13 Alza Corporation Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung
CA2408323C (en) * 2000-05-08 2012-06-12 The University Of British Columbia Drug delivery systems for photodynamic therapy
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
US20060216342A1 (en) * 2003-04-18 2006-09-28 Torchilin Vladimir P Micelle delivery system loaded with a pharmaceutical agent
US20060251795A1 (en) * 2005-05-05 2006-11-09 Boris Kobrin Controlled vapor deposition of biocompatible coatings for medical devices

Also Published As

Publication number Publication date
US20040013717A1 (en) 2004-01-22
ES2306785T3 (es) 2008-11-16
EP1465590B1 (de) 2008-03-26
WO2003037295A2 (en) 2003-05-08
WO2003037295A3 (en) 2004-07-29
EP1465590A2 (de) 2004-10-13
ATE390121T1 (de) 2008-04-15
CA2466103C (en) 2010-06-15
CA2466103A1 (en) 2003-05-08
AU2002336867A1 (en) 2003-05-12
DE60225844T2 (de) 2009-04-09

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