DE60225532D1 - Membran für eine einkapselungskammer von zellen die zumindestens einen wirkstoff erzeugen und bioartifizielles organ enthaltend diese membran - Google Patents

Membran für eine einkapselungskammer von zellen die zumindestens einen wirkstoff erzeugen und bioartifizielles organ enthaltend diese membran

Info

Publication number
DE60225532D1
DE60225532D1 DE60225532T DE60225532T DE60225532D1 DE 60225532 D1 DE60225532 D1 DE 60225532D1 DE 60225532 T DE60225532 T DE 60225532T DE 60225532 T DE60225532 T DE 60225532T DE 60225532 D1 DE60225532 D1 DE 60225532D1
Authority
DE
Germany
Prior art keywords
membrane
bioartific
active substance
organ containing
cells generating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60225532T
Other languages
English (en)
Other versions
DE60225532T2 (de
Inventor
Gilbert Legeay
Patrick Bertrand
Alain Belcourt
Laurence Kessler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Catholique de Louvain UCL
ASS POUR LES TRANSFERTS DE TEC
Centre Europeen dEtude du Diabete CEED
Original Assignee
Universite Catholique de Louvain UCL
ASS POUR LES TRANSFERTS DE TEC
Centre Europeen dEtude du Diabete CEED
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Catholique de Louvain UCL, ASS POUR LES TRANSFERTS DE TEC, Centre Europeen dEtude du Diabete CEED filed Critical Universite Catholique de Louvain UCL
Application granted granted Critical
Publication of DE60225532D1 publication Critical patent/DE60225532D1/de
Publication of DE60225532T2 publication Critical patent/DE60225532T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Laminated Bodies (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE60225532T 2001-01-30 2002-01-29 Membran für eine einkapselungskammer von zellen die zumindestens einen wirkstoff erzeugen und bioartifizielles organ enthaltend diese membran Expired - Lifetime DE60225532T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0101248 2001-01-30
FR0101248A FR2820057A1 (fr) 2001-01-30 2001-01-30 Membrane pour chambre d'encapsulation de cellules produisant au moins une substance biologiquement active et organe bio-artificiel comprenant une telle membrane
PCT/FR2002/000347 WO2002060409A1 (fr) 2001-01-30 2002-01-29 Membrane pour chambre d'encapsulation de cellules produisant au moins une substance biologiquement active et organe bio-artificiel comprenant une telle membrane.

Publications (2)

Publication Number Publication Date
DE60225532D1 true DE60225532D1 (de) 2008-04-24
DE60225532T2 DE60225532T2 (de) 2009-04-02

Family

ID=8859410

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60225532T Expired - Lifetime DE60225532T2 (de) 2001-01-30 2002-01-29 Membran für eine einkapselungskammer von zellen die zumindestens einen wirkstoff erzeugen und bioartifizielles organ enthaltend diese membran

Country Status (7)

Country Link
US (1) US7056726B2 (de)
EP (1) EP1357896B1 (de)
AT (1) ATE388694T1 (de)
DE (1) DE60225532T2 (de)
ES (1) ES2303852T3 (de)
FR (1) FR2820057A1 (de)
WO (1) WO2002060409A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10217440A1 (de) * 2002-04-18 2003-11-06 Basf Ag Verwendung hydrophob modifizierter Copolymere auf Basis von N-Vinylmonomeren zur Herstellung von Membranen
RU2007129779A (ru) * 2005-01-06 2009-02-20 Астразенека Аб (Se) Новые соединения пиридина
US7855070B2 (en) * 2005-07-08 2010-12-21 Georgia Tech Research Corporation Centimeter-scale, integrated diagnostics incubator for biological culturing
US20080312208A1 (en) * 2005-07-13 2008-12-18 Astrazeneca Ab Pyridine Analogues
TW200815426A (en) * 2006-06-28 2008-04-01 Astrazeneca Ab New pyridine analogues II 333
TW200811133A (en) * 2006-07-04 2008-03-01 Astrazeneca Ab New pyridine analogues III 334
KR20090020712A (ko) * 2006-07-04 2009-02-26 아스트라제네카 아베 신규한 피리딘 유도체
US20080032992A1 (en) * 2006-07-04 2008-02-07 Astrazeneca Ab New Pyridine Analogues V
JP2009542641A (ja) * 2006-07-04 2009-12-03 アストラゼネカ アクチボラグ 新規ピリジン類縁体
AR064867A1 (es) * 2007-01-12 2009-04-29 Astrazeneca Ab Analogos de piridina viii 518
UY30867A1 (es) * 2007-01-12 2008-09-02 Astrazeneca Ab Nuevos analogos de piridina vii 543
AU2008203953A1 (en) * 2007-01-12 2008-07-17 Astrazeneca Ab Pyridine compounds and their use as P2Y12 antagonists.
TW200902513A (en) * 2007-07-13 2009-01-16 Astrazeneca Ab New pyridine analogues
FR2960783B1 (fr) * 2010-06-04 2012-07-27 Ass Pour Les Transferts De Technologies Du Mans Membrane fonctionnalisee pour chambre d'encapsulation de cellules produisant au moins une substance d'interet therapeutique et organe bioartificiel comprenant une telle membrane
FR2962898B1 (fr) 2010-07-22 2012-08-17 Statice Sante Poche pour former un organe artificiel implantable
US20140114436A1 (en) * 2011-02-17 2014-04-24 Patrick A. Tresco Medical devices and methods for improving the biocompatibility of medical devices
WO2012113859A1 (en) 2011-02-23 2012-08-30 Université Catholique de Louvain Modified pig islets for diabetes treatment
FR3014316B1 (fr) 2013-12-10 2017-01-20 Defymed Organe bioartificiel
CA2945240C (en) 2014-04-11 2021-08-03 Universite Catholique De Louvain Transgenic pig islets and uses thereof for treating diabetes
EP3095509A1 (de) 2015-05-18 2016-11-23 Defymed Funktionalisierte membrane für biokünstliche organe
EP3318294A1 (de) 2016-11-08 2018-05-09 Defymed Kit zur in situ-ausgabe einer verbindung von interesse
EP3428264A1 (de) 2017-07-12 2019-01-16 Defymed Nicht faltbarer beutel zur formung eines implantierbaren künstlichen organs
JP2019097442A (ja) * 2017-11-30 2019-06-24 株式会社日立製作所 免疫隔離デバイス
EP3892259A1 (de) 2020-04-09 2021-10-13 Defymed Membranen für medizinische vorrichtungen
CA3179703A1 (en) 2020-04-09 2021-10-14 Defymed Membranes for medical devices
CN114949369B (zh) * 2021-02-19 2023-09-05 清华大学 一种人工组织器官的封装装置及其制备方法和应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL174020C (nl) * 1973-09-07 1984-04-16 Sumitomo Chemical Co Werkwijze voor het vervaardigen van een membraan voor het scheiden van stoffen, en het vervaardigde membraan.
JPS568645B2 (de) * 1974-09-05 1981-02-25
IL64967A0 (en) * 1981-03-17 1982-04-30 Aligena Ag Semipermeable membranes containing modified polysulfones,their manufacture and their use
US4906375A (en) * 1984-07-14 1990-03-06 Fresenius, Ag Asymmetrical microporous hollow fiber for hemodialysis
JPH064713B2 (ja) * 1988-07-22 1994-01-19 テルモ株式会社 生体適合性材料
AU4529289A (en) * 1988-10-17 1990-05-14 Sepracor, Inc. Process for the covalent surface modification of hydrophobic polymers and articles made therefrom
US5202025A (en) * 1989-04-12 1993-04-13 Terumo Kabushiki Kaisha Porous membrane and method for preparing the same
US4944879A (en) * 1989-07-27 1990-07-31 Millipore Corporation Membrane having hydrophilic surface
US5798261A (en) * 1989-10-31 1998-08-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Distributed pore chemistry in porous organic polymers
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5226902A (en) * 1991-07-30 1993-07-13 University Of Utah Pulsatile drug delivery device using stimuli sensitive hydrogel
US5266391A (en) * 1992-12-18 1993-11-30 Hoechst Celanese Corporation Composite porous membranes
WO1994018906A1 (en) * 1993-02-18 1994-09-01 New England Deaconess Hospital, Corp. Implantable artificial organ
US5620883A (en) * 1994-04-01 1997-04-15 The Johns Hopkins University Living cells microencapsulated in a polymeric membrane having two layers
WO1997010807A1 (en) * 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
EP0822857A1 (de) * 1996-02-23 1998-02-11 Circe Biomedical, Inc. Neuartige künstliche bauchspeicheldrüse
DK0889951T3 (da) * 1996-03-29 2004-07-26 Radiometer Medical As Sensor og modificeret menbran til denne sensor
AUPO251096A0 (en) * 1996-09-23 1996-10-17 Cardiac Crc Nominees Pty Limited Polysiloxane-containing polyurethane elastomeric compositions
AR009439A1 (es) * 1996-12-23 2000-04-12 Novartis Ag Un articulo que comprende un sustrato con un recubrimiento polimerico primario que porta grupos reactivos predominantemente en su superficie, unmetodo para preparar dicho articulo, un articulo que posee un recubrimiento de tipo hibrido y una lente de contacto
US5942120A (en) * 1997-12-04 1999-08-24 Wilkinson; Kenneth Composite microporous ultrafiltration membrane, method of making thereof, and separation methods
JP4605734B2 (ja) * 1999-06-21 2011-01-05 ザ ジェネラル ホスピタル コーポレイション 臓器補助装置のための細胞培養システム及び方法

Also Published As

Publication number Publication date
DE60225532T2 (de) 2009-04-02
ATE388694T1 (de) 2008-03-15
ES2303852T3 (es) 2008-09-01
US20040137063A1 (en) 2004-07-15
WO2002060409A8 (fr) 2002-10-24
WO2002060409A1 (fr) 2002-08-08
FR2820057A1 (fr) 2002-08-02
US7056726B2 (en) 2006-06-06
EP1357896A1 (de) 2003-11-05
EP1357896B1 (de) 2008-03-12

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