DE60223340D1 - Serpin-arzneistoffe zur behandlung einer hiv-infektion und verfahren zu deren verwendung - Google Patents

Serpin-arzneistoffe zur behandlung einer hiv-infektion und verfahren zu deren verwendung

Info

Publication number
DE60223340D1
DE60223340D1 DE60223340T DE60223340T DE60223340D1 DE 60223340 D1 DE60223340 D1 DE 60223340D1 DE 60223340 T DE60223340 T DE 60223340T DE 60223340 T DE60223340 T DE 60223340T DE 60223340 D1 DE60223340 D1 DE 60223340D1
Authority
DE
Germany
Prior art keywords
hiv infection
treatment
serpine
drugs
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60223340T
Other languages
English (en)
Other versions
DE60223340T2 (de
Inventor
Ralf Geiben Lynn
Bruce D Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE60223340D1 publication Critical patent/DE60223340D1/de
Publication of DE60223340T2 publication Critical patent/DE60223340T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60223340T 2001-01-26 2002-01-25 Serpin-arzneistoffe zur behandlung einer hiv-infektion und verfahren zu deren verwendung Expired - Lifetime DE60223340T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26433801P 2001-01-26 2001-01-26
US264338P 2001-01-26
PCT/US2002/002309 WO2002058638A2 (en) 2001-01-26 2002-01-25 Serpin drugs for treatment of hiv infection and method of use thereof

Publications (2)

Publication Number Publication Date
DE60223340D1 true DE60223340D1 (de) 2007-12-20
DE60223340T2 DE60223340T2 (de) 2008-08-28

Family

ID=23005599

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223340T Expired - Lifetime DE60223340T2 (de) 2001-01-26 2002-01-25 Serpin-arzneistoffe zur behandlung einer hiv-infektion und verfahren zu deren verwendung

Country Status (7)

Country Link
US (2) US20020127698A1 (de)
EP (1) EP1362127B1 (de)
AT (1) ATE377657T1 (de)
AU (1) AU2002248384A1 (de)
DE (1) DE60223340T2 (de)
ES (1) ES2296914T3 (de)
WO (1) WO2002058638A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10045047A1 (de) * 2000-09-12 2002-03-21 Beate Kehrel Arzneimittel enthaltend aktiviertes Antithrombin III
US20110008889A1 (en) * 2001-01-26 2011-01-13 Ralf Geiben-Lynn Serpin drugs for treatment of hiv infection and method of use thereof
US7326692B2 (en) * 2001-11-14 2008-02-05 The University Of Chicago Induction of immunity using inhibitors of granzymes
US7218948B2 (en) * 2003-02-24 2007-05-15 Qualcomm Incorporated Method of transmitting pilot tones in a multi-sector cell, including null pilot tones, for generating channel quality indicators
US9661519B2 (en) 2003-02-24 2017-05-23 Qualcomm Incorporated Efficient reporting of information in a wireless communication system
US8811348B2 (en) * 2003-02-24 2014-08-19 Qualcomm Incorporated Methods and apparatus for generating, communicating, and/or using information relating to self-noise
US9544860B2 (en) * 2003-02-24 2017-01-10 Qualcomm Incorporated Pilot signals for use in multi-sector cells
US7498130B2 (en) 2003-05-13 2009-03-03 Massachusetts General Hospital Method of reducing viral load
US20040229778A1 (en) * 2003-05-13 2004-11-18 Elmaleh David R. Pharmaceutical compositions of antithrombin III for the treatment of retroviral diseases
JP2008505912A (ja) * 2004-07-07 2008-02-28 ザ ジェネラル ホスピタル コーポレーション 全血及び血漿におけるａｔｉｉｉの直接的活性化法
US8503938B2 (en) * 2004-10-14 2013-08-06 Qualcomm Incorporated Methods and apparatus for determining, communicating and using information including loading factors which can be used for interference control purposes
US20060092881A1 (en) * 2004-10-14 2006-05-04 Rajiv Laroia Methods and apparatus for determining, communicating and using information which can be used for interference control purposes
KR100911087B1 (ko) * 2004-10-14 2009-08-06 콸콤 인코포레이티드 간섭 제어 목적으로 사용될 수 있는 정보를 결정, 통신, 및사용하기 위한 방법 및 장치
ES2565543T3 (es) * 2005-01-24 2016-04-05 Board Of Regents, The University Of Texas System Construcciones de fusión a Fc de unión a fosfatidilserina y su uso terapéutico
US9191840B2 (en) * 2005-10-14 2015-11-17 Qualcomm Incorporated Methods and apparatus for determining, communicating and using information which can be used for interference control
US8694042B2 (en) 2005-10-14 2014-04-08 Qualcomm Incorporated Method and apparatus for determining a base station's transmission power budget
US20090227518A1 (en) * 2005-12-02 2009-09-10 The Regents Of The University Of Colorado Compositions and methods for treating actin-mediated medical conditions
US9125093B2 (en) * 2005-12-22 2015-09-01 Qualcomm Incorporated Methods and apparatus related to custom control channel reporting formats
US9119220B2 (en) * 2005-12-22 2015-08-25 Qualcomm Incorporated Methods and apparatus for communicating backlog related information
US20070253449A1 (en) * 2005-12-22 2007-11-01 Arnab Das Methods and apparatus related to determining, communicating, and/or using delay information
US9572179B2 (en) 2005-12-22 2017-02-14 Qualcomm Incorporated Methods and apparatus for communicating transmission backlog information
US9148795B2 (en) * 2005-12-22 2015-09-29 Qualcomm Incorporated Methods and apparatus for flexible reporting of control information
US20070149132A1 (en) 2005-12-22 2007-06-28 Junyl Li Methods and apparatus related to selecting control channel reporting formats
US9451491B2 (en) * 2005-12-22 2016-09-20 Qualcomm Incorporated Methods and apparatus relating to generating and transmitting initial and additional control information report sets in a wireless system
US9473265B2 (en) 2005-12-22 2016-10-18 Qualcomm Incorporated Methods and apparatus for communicating information utilizing a plurality of dictionaries
US9125092B2 (en) 2005-12-22 2015-09-01 Qualcomm Incorporated Methods and apparatus for reporting and/or using control information
US8437251B2 (en) 2005-12-22 2013-05-07 Qualcomm Incorporated Methods and apparatus for communicating transmission backlog information
US9338767B2 (en) * 2005-12-22 2016-05-10 Qualcomm Incorporated Methods and apparatus of implementing and/or using a dedicated control channel
US9137072B2 (en) 2005-12-22 2015-09-15 Qualcomm Incorporated Methods and apparatus for communicating control information
US8514771B2 (en) * 2005-12-22 2013-08-20 Qualcomm Incorporated Methods and apparatus for communicating and/or using transmission power information
US20070243882A1 (en) * 2006-04-12 2007-10-18 Qualcomm Incorporated Method and apparatus for locating a wireless local area network associated with a wireless wide area network
RU2013113723A (ru) * 2010-09-14 2014-10-20 Ф.Хоффманн-Ля Рош Аг Гибридный полипептид с серпиновым "пальцем"

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE392038B (sv) * 1971-09-08 1977-03-14 Kabi Ab Forfarande for isolering av antitrombin ur blod eller blodprodukter
JPS597693B2 (ja) * 1978-01-07 1984-02-20 株式会社ミドリ十字 抗トロンビン製剤及びその製法
DE3170001D1 (en) * 1980-09-30 1985-05-23 Bayer Ag Method for the production of an antithrombin-heparin complex and pharmaceutical compositions containing the complex
EP0090505B1 (de) 1982-03-03 1990-08-08 Genentech, Inc. Menschliches Antithrombin III, DNS Sequenzen dafür, Expressions- und Klonierungsvektoren die solche Sequenzen enthalten und damit transformierte Zellkulturen, Verfahren zur Expression von Menschlichem Antithrombin III und diese enthaltende pharmazeutische Zusammensetzungen
US4689323A (en) * 1983-09-26 1987-08-25 Miles Laboratories, Inc. Covalently bound heparin--antithrombin-III complex
CA1341379C (en) 1988-04-28 2002-07-23 Welfide Corporation Purified antithrombin-iii and methods of producing the same
US5610286A (en) 1991-11-04 1997-03-11 The Regents Of The University Of California DNA's encoding natural killer cell enhancing factor
US5376633A (en) * 1992-09-30 1994-12-27 Lezdey; John Method for deactivating viruses in blood component containers
WO1996010638A1 (en) 1994-09-30 1996-04-11 Ppl Therapeutics (Scotland) Ltd. Alpha-1-antitrypsin and antithrombine-iii variants
WO1996039424A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Natural killer cell enhancing factor c
AU3719100A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of viral infections

Also Published As

Publication number Publication date
WO2002058638A2 (en) 2002-08-01
US7510828B2 (en) 2009-03-31
EP1362127A4 (de) 2004-09-22
DE60223340T2 (de) 2008-08-28
US20020127698A1 (en) 2002-09-12
EP1362127A2 (de) 2003-11-19
EP1362127B1 (de) 2007-11-07
WO2002058638A3 (en) 2002-09-26
US20050058637A1 (en) 2005-03-17
ES2296914T3 (es) 2008-05-01
ATE377657T1 (de) 2007-11-15
AU2002248384A1 (en) 2002-08-06

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