DE60222672D1 - Verfahren zur herstellung von lipid ii - Google Patents

Verfahren zur herstellung von lipid ii

Info

Publication number
DE60222672D1
DE60222672D1 DE60222672T DE60222672T DE60222672D1 DE 60222672 D1 DE60222672 D1 DE 60222672D1 DE 60222672 T DE60222672 T DE 60222672T DE 60222672 T DE60222672 T DE 60222672T DE 60222672 D1 DE60222672 D1 DE 60222672D1
Authority
DE
Germany
Prior art keywords
cell wall
bacterial cell
wall biosynthesis
preparing lipid
lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60222672T
Other languages
English (en)
Other versions
DE60222672T2 (de
Inventor
Larry Chris Blaszczak
Scott Carl Mauldin
Michael Scott Vannieuwenhze
Mohammad Sadegh Zia-Ebrahimi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/833,647 external-priority patent/US7169919B2/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE60222672D1 publication Critical patent/DE60222672D1/de
Application granted granted Critical
Publication of DE60222672T2 publication Critical patent/DE60222672T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60222672T 2001-04-18 2002-04-18 Verfahren zur herstellung von lipid ii Expired - Fee Related DE60222672T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US833647 2001-04-18
US09/833,647 US7169919B2 (en) 2000-04-18 2001-04-18 Process for preparing lipid II
PCT/US2002/008266 WO2002085929A1 (en) 2001-04-18 2002-04-18 Process for preparing lipid ii

Publications (2)

Publication Number Publication Date
DE60222672D1 true DE60222672D1 (de) 2007-11-08
DE60222672T2 DE60222672T2 (de) 2008-07-24

Family

ID=25264939

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60222672T Expired - Fee Related DE60222672T2 (de) 2001-04-18 2002-04-18 Verfahren zur herstellung von lipid ii

Country Status (6)

Country Link
EP (1) EP1417223B8 (de)
JP (1) JP2005529838A (de)
AT (1) ATE374207T1 (de)
DE (1) DE60222672T2 (de)
ES (1) ES2292750T3 (de)
WO (1) WO2002085929A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1275731A1 (de) * 2001-07-09 2003-01-15 Universiteit Utrecht Holding B.V. Verfahren zur Herstellung von Lipid II und Verwendung des so hergestellten Lipid II
CN100554279C (zh) * 2003-09-17 2009-10-28 伊莱利利公司 用于疾病免疫干预的合成多糖抗原
CN113214335A (zh) * 2020-01-21 2021-08-06 上海医药工业研究院 Lipid X中间体及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7169919B2 (en) * 2000-04-18 2007-01-30 Eli Lilly And Company Process for preparing lipid II

Also Published As

Publication number Publication date
WO2002085929A1 (en) 2002-10-31
JP2005529838A (ja) 2005-10-06
ATE374207T1 (de) 2007-10-15
EP1417223A1 (de) 2004-05-12
EP1417223B1 (de) 2007-09-26
EP1417223B8 (de) 2008-02-13
ES2292750T3 (es) 2008-03-16
DE60222672T2 (de) 2008-07-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee