DE60221894D1 - Vollständige synthese der galanthamin, deren analogen und derivaten - Google Patents
Vollständige synthese der galanthamin, deren analogen und derivatenInfo
- Publication number
- DE60221894D1 DE60221894D1 DE60221894T DE60221894T DE60221894D1 DE 60221894 D1 DE60221894 D1 DE 60221894D1 DE 60221894 T DE60221894 T DE 60221894T DE 60221894 T DE60221894 T DE 60221894T DE 60221894 D1 DE60221894 D1 DE 60221894D1
- Authority
- DE
- Germany
- Prior art keywords
- galanthamine
- derivatives
- analog
- group
- complete synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0107859A FR2826005B1 (fr) | 2001-06-15 | 2001-06-15 | Synthese totale de la galanthamine, de ses analogues et de ses derives |
FR0107859 | 2001-06-15 | ||
PCT/FR2002/002045 WO2002102803A1 (fr) | 2001-06-15 | 2002-06-14 | Synthese totale de la galanthamine, de ses analogues et de ses derives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60221894D1 true DE60221894D1 (de) | 2007-09-27 |
DE60221894T2 DE60221894T2 (de) | 2008-04-30 |
Family
ID=8864355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60221894T Expired - Lifetime DE60221894T2 (de) | 2001-06-15 | 2002-06-14 | Totalsynthese von Galanthamin, von dessen Analoga und von dessen Derivaten |
Country Status (7)
Country | Link |
---|---|
US (2) | USRE41366E1 (de) |
EP (1) | EP1458724B1 (de) |
AT (1) | ATE370143T1 (de) |
DE (1) | DE60221894T2 (de) |
ES (1) | ES2292776T3 (de) |
FR (1) | FR2826005B1 (de) |
WO (1) | WO2002102803A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT414125B (de) * | 2003-09-29 | 2006-09-15 | Sanochemia Pharmazeutika Ag | Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln |
DE602006016441D1 (de) * | 2005-05-13 | 2010-10-07 | Alza Corp | Mehrlagiges arzneimittelausbringsystem mit sperre gegen reservoirmaterialfluss |
US20070104771A1 (en) * | 2005-09-23 | 2007-05-10 | Jay Audett | Transdermal galantamine delivery system |
CN104592243B (zh) * | 2014-12-19 | 2016-08-24 | 北京大学 | 加兰他敏和力克拉敏的不对称合成方法 |
-
2001
- 2001-06-15 FR FR0107859A patent/FR2826005B1/fr not_active Expired - Fee Related
-
2002
- 2002-06-14 AT AT02745535T patent/ATE370143T1/de not_active IP Right Cessation
- 2002-06-14 DE DE60221894T patent/DE60221894T2/de not_active Expired - Lifetime
- 2002-06-14 EP EP02745535A patent/EP1458724B1/de not_active Expired - Lifetime
- 2002-06-14 US US12/283,904 patent/USRE41366E1/en not_active Expired - Fee Related
- 2002-06-14 US US10/480,722 patent/US7109327B2/en not_active Ceased
- 2002-06-14 WO PCT/FR2002/002045 patent/WO2002102803A1/fr active IP Right Grant
- 2002-06-14 ES ES02745535T patent/ES2292776T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2002102803A1 (fr) | 2002-12-27 |
EP1458724A1 (de) | 2004-09-22 |
ATE370143T1 (de) | 2007-09-15 |
FR2826005A1 (fr) | 2002-12-20 |
ES2292776T3 (es) | 2008-03-16 |
USRE41366E1 (en) | 2010-06-01 |
US20050065338A1 (en) | 2005-03-24 |
US7109327B2 (en) | 2006-09-19 |
FR2826005B1 (fr) | 2004-07-16 |
EP1458724B1 (de) | 2007-08-15 |
DE60221894T2 (de) | 2008-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |