DE60221883D1 - Screeningverfahren für einen auf die zellwand wirkenden arzneistoff - Google Patents

Screeningverfahren für einen auf die zellwand wirkenden arzneistoff

Info

Publication number
DE60221883D1
DE60221883D1 DE60221883T DE60221883T DE60221883D1 DE 60221883 D1 DE60221883 D1 DE 60221883D1 DE 60221883 T DE60221883 T DE 60221883T DE 60221883 T DE60221883 T DE 60221883T DE 60221883 D1 DE60221883 D1 DE 60221883D1
Authority
DE
Germany
Prior art keywords
cell wall
reporter protein
targeting site
screening method
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60221883T
Other languages
English (en)
Other versions
DE60221883T2 (de
Inventor
Akihiro Kitamura
Ryohei Nakajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60221883D1 publication Critical patent/DE60221883D1/de
Publication of DE60221883T2 publication Critical patent/DE60221883T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60221883T 2001-10-22 2002-10-22 Screeningverfahren für einen auf die zellwand wirkenden arzneistoff Expired - Lifetime DE60221883T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001323293 2001-10-22
JP2001323293 2001-10-22
PCT/JP2002/010932 WO2003035898A1 (fr) 2001-10-22 2002-10-22 Methode de criblage d'un medicament agissant sur la paroi cellulaire

Publications (2)

Publication Number Publication Date
DE60221883D1 true DE60221883D1 (de) 2007-09-27
DE60221883T2 DE60221883T2 (de) 2008-04-30

Family

ID=19140207

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60221883T Expired - Lifetime DE60221883T2 (de) 2001-10-22 2002-10-22 Screeningverfahren für einen auf die zellwand wirkenden arzneistoff

Country Status (9)

Country Link
US (1) US7459268B2 (de)
EP (1) EP1445327B1 (de)
JP (1) JP4204471B2 (de)
AT (1) ATE370243T1 (de)
CA (1) CA2464396A1 (de)
DE (1) DE60221883T2 (de)
ES (1) ES2294172T3 (de)
NO (1) NO20042089L (de)
WO (1) WO2003035898A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4204471B2 (ja) 2001-10-22 2009-01-07 第一三共株式会社 細胞壁作用性薬剤のスクリーニング方法
JP4954203B2 (ja) * 2005-09-22 2012-06-13 サントリーホールディングス株式会社 細胞壁マンノプロテインをコードする遺伝子及びその用途
TWI428091B (zh) * 2007-10-23 2014-03-01 Du Pont 殺真菌劑混合物
US11643438B2 (en) 2018-07-20 2023-05-09 The Board Of Regents Of The University Of Oklahoma Antimicrobial peptides and methods of use
CN115094142B (zh) * 2022-07-19 2024-05-28 中国医学科学院肿瘤医院 用于诊断肺肠型腺癌的甲基化标志物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0673427T3 (da) 1992-07-08 2003-07-21 Unilever Nv Enzymatisk proces under anvendelse af enzymer immobiliseret på cellevæggen af en eukaryotisk mikrobiel celle ved fremstilling af et fusionsprotein
JPH0956384A (ja) * 1995-08-25 1997-03-04 Toray Ind Inc 細胞の標識方法
EP0916726A1 (de) * 1997-11-13 1999-05-19 Rijksuniversiteit te Groningen Befestigungs-Substanzen an Mikroorganismen
AU4566699A (en) * 1998-06-25 2000-01-10 Collaborative Group, Ltd., The Beta(1,6)-glucan synthesis and cell wall assembly assay
JP2000102387A (ja) 1998-09-29 2000-04-11 Daicel Chem Ind Ltd 発光蛋白質発現組換えベクター、及びこの組換えベクターにより形質転換された酵母
DE60135215D1 (de) 2000-05-01 2008-09-18 Daiichi Sankyo Co Ltd Verfahren zum screening von auf zellwände wirkenden arzneistoffen
JP4204471B2 (ja) 2001-10-22 2009-01-07 第一三共株式会社 細胞壁作用性薬剤のスクリーニング方法

Also Published As

Publication number Publication date
EP1445327A4 (de) 2005-09-14
ATE370243T1 (de) 2007-09-15
DE60221883T2 (de) 2008-04-30
US20050069965A1 (en) 2005-03-31
WO2003035898A1 (fr) 2003-05-01
JPWO2003035898A1 (ja) 2005-02-10
NO20042089L (no) 2004-05-21
EP1445327B1 (de) 2007-08-15
ES2294172T3 (es) 2008-04-01
US7459268B2 (en) 2008-12-02
JP4204471B2 (ja) 2009-01-07
CA2464396A1 (en) 2003-05-01
EP1445327A1 (de) 2004-08-11

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