DE60221883D1 - Screeningverfahren für einen auf die zellwand wirkenden arzneistoff - Google Patents
Screeningverfahren für einen auf die zellwand wirkenden arzneistoffInfo
- Publication number
- DE60221883D1 DE60221883D1 DE60221883T DE60221883T DE60221883D1 DE 60221883 D1 DE60221883 D1 DE 60221883D1 DE 60221883 T DE60221883 T DE 60221883T DE 60221883 T DE60221883 T DE 60221883T DE 60221883 D1 DE60221883 D1 DE 60221883D1
- Authority
- DE
- Germany
- Prior art keywords
- cell wall
- reporter protein
- targeting site
- screening method
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001323293 | 2001-10-22 | ||
JP2001323293 | 2001-10-22 | ||
PCT/JP2002/010932 WO2003035898A1 (fr) | 2001-10-22 | 2002-10-22 | Methode de criblage d'un medicament agissant sur la paroi cellulaire |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60221883D1 true DE60221883D1 (de) | 2007-09-27 |
DE60221883T2 DE60221883T2 (de) | 2008-04-30 |
Family
ID=19140207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60221883T Expired - Lifetime DE60221883T2 (de) | 2001-10-22 | 2002-10-22 | Screeningverfahren für einen auf die zellwand wirkenden arzneistoff |
Country Status (9)
Country | Link |
---|---|
US (1) | US7459268B2 (de) |
EP (1) | EP1445327B1 (de) |
JP (1) | JP4204471B2 (de) |
AT (1) | ATE370243T1 (de) |
CA (1) | CA2464396A1 (de) |
DE (1) | DE60221883T2 (de) |
ES (1) | ES2294172T3 (de) |
NO (1) | NO20042089L (de) |
WO (1) | WO2003035898A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4204471B2 (ja) | 2001-10-22 | 2009-01-07 | 第一三共株式会社 | 細胞壁作用性薬剤のスクリーニング方法 |
JP4954203B2 (ja) * | 2005-09-22 | 2012-06-13 | サントリーホールディングス株式会社 | 細胞壁マンノプロテインをコードする遺伝子及びその用途 |
TWI428091B (zh) * | 2007-10-23 | 2014-03-01 | Du Pont | 殺真菌劑混合物 |
US11643438B2 (en) | 2018-07-20 | 2023-05-09 | The Board Of Regents Of The University Of Oklahoma | Antimicrobial peptides and methods of use |
CN115094142B (zh) * | 2022-07-19 | 2024-05-28 | 中国医学科学院肿瘤医院 | 用于诊断肺肠型腺癌的甲基化标志物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0673427T3 (da) | 1992-07-08 | 2003-07-21 | Unilever Nv | Enzymatisk proces under anvendelse af enzymer immobiliseret på cellevæggen af en eukaryotisk mikrobiel celle ved fremstilling af et fusionsprotein |
JPH0956384A (ja) * | 1995-08-25 | 1997-03-04 | Toray Ind Inc | 細胞の標識方法 |
EP0916726A1 (de) * | 1997-11-13 | 1999-05-19 | Rijksuniversiteit te Groningen | Befestigungs-Substanzen an Mikroorganismen |
AU4566699A (en) * | 1998-06-25 | 2000-01-10 | Collaborative Group, Ltd., The | Beta(1,6)-glucan synthesis and cell wall assembly assay |
JP2000102387A (ja) | 1998-09-29 | 2000-04-11 | Daicel Chem Ind Ltd | 発光蛋白質発現組換えベクター、及びこの組換えベクターにより形質転換された酵母 |
DE60135215D1 (de) | 2000-05-01 | 2008-09-18 | Daiichi Sankyo Co Ltd | Verfahren zum screening von auf zellwände wirkenden arzneistoffen |
JP4204471B2 (ja) | 2001-10-22 | 2009-01-07 | 第一三共株式会社 | 細胞壁作用性薬剤のスクリーニング方法 |
-
2002
- 2002-10-22 JP JP2003538398A patent/JP4204471B2/ja not_active Expired - Fee Related
- 2002-10-22 ES ES02775378T patent/ES2294172T3/es not_active Expired - Lifetime
- 2002-10-22 WO PCT/JP2002/010932 patent/WO2003035898A1/ja active IP Right Grant
- 2002-10-22 CA CA002464396A patent/CA2464396A1/en not_active Abandoned
- 2002-10-22 EP EP02775378A patent/EP1445327B1/de not_active Expired - Lifetime
- 2002-10-22 US US10/492,202 patent/US7459268B2/en not_active Expired - Fee Related
- 2002-10-22 AT AT02775378T patent/ATE370243T1/de not_active IP Right Cessation
- 2002-10-22 DE DE60221883T patent/DE60221883T2/de not_active Expired - Lifetime
-
2004
- 2004-05-21 NO NO20042089A patent/NO20042089L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1445327A4 (de) | 2005-09-14 |
ATE370243T1 (de) | 2007-09-15 |
DE60221883T2 (de) | 2008-04-30 |
US20050069965A1 (en) | 2005-03-31 |
WO2003035898A1 (fr) | 2003-05-01 |
JPWO2003035898A1 (ja) | 2005-02-10 |
NO20042089L (no) | 2004-05-21 |
EP1445327B1 (de) | 2007-08-15 |
ES2294172T3 (es) | 2008-04-01 |
US7459268B2 (en) | 2008-12-02 |
JP4204471B2 (ja) | 2009-01-07 |
CA2464396A1 (en) | 2003-05-01 |
EP1445327A1 (de) | 2004-08-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |