DE60217112T2 - Fluorhaltige dreiphasen- und andere mehrphasensysteme - Google Patents

Fluorhaltige dreiphasen- und andere mehrphasensysteme Download PDF

Info

Publication number
DE60217112T2
DE60217112T2 DE60217112T DE60217112T DE60217112T2 DE 60217112 T2 DE60217112 T2 DE 60217112T2 DE 60217112 T DE60217112 T DE 60217112T DE 60217112 T DE60217112 T DE 60217112T DE 60217112 T2 DE60217112 T2 DE 60217112T2
Authority
DE
Germany
Prior art keywords
phase
compound
fluorous
fluorine
organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60217112T
Other languages
German (de)
English (en)
Other versions
DE60217112D1 (de
Inventor
P. Dennis Pittsburgh CURRAN
G. Stephen Pittsburgh WEBER
Hiroyuki Nakamura
Bruno Linclau
Lifang La Mesa SUN
Ilhyong Ryu
Hiroshi Matsubara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/877,944 external-priority patent/US6734318B2/en
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Application granted granted Critical
Publication of DE60217112D1 publication Critical patent/DE60217112D1/de
Publication of DE60217112T2 publication Critical patent/DE60217112T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/04Substitution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00Other general methods
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/32Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen
    • C07C1/325Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a metal atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/013Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/02Preparation of halogenated hydrocarbons by addition of halogens to unsaturated hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/46Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
DE60217112T 2001-06-08 2002-06-05 Fluorhaltige dreiphasen- und andere mehrphasensysteme Expired - Fee Related DE60217112T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US877944 1978-02-15
US94345 1987-09-08
US09/877,944 US6734318B2 (en) 2001-06-08 2001-06-08 Fluorous triphase and other multiphase systems
US10/094,345 US6897331B2 (en) 2001-06-08 2002-03-08 Fluorous triphase and other multiphase systems
PCT/US2002/017829 WO2002100802A2 (en) 2001-06-08 2002-06-05 Fluorous triphase and other multiphase systems

Publications (2)

Publication Number Publication Date
DE60217112D1 DE60217112D1 (de) 2007-02-08
DE60217112T2 true DE60217112T2 (de) 2007-06-06

Family

ID=26788749

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60217112T Expired - Fee Related DE60217112T2 (de) 2001-06-08 2002-06-05 Fluorhaltige dreiphasen- und andere mehrphasensysteme

Country Status (8)

Country Link
US (1) US6897331B2 (enExample)
EP (1) EP1404687B1 (enExample)
JP (1) JP2004529981A (enExample)
AT (1) ATE349453T1 (enExample)
AU (1) AU2002314930A1 (enExample)
CA (1) CA2449445C (enExample)
DE (1) DE60217112T2 (enExample)
WO (1) WO2002100802A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6897331B2 (en) 2001-06-08 2005-05-24 University Of Pittsburgh Fluorous triphase and other multiphase systems
US6734318B2 (en) 2001-06-08 2004-05-11 University Of Pittsburgh Fluorous triphase and other multiphase systems
WO2004007407A2 (en) * 2002-07-11 2004-01-22 Fluorous Technologies Incorporated Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
US7135598B2 (en) * 2002-09-06 2006-11-14 University Of Pittsburgh N-vinylformamide derivatives, polymers formed therefrom and synthesis thereof
US7875752B2 (en) * 2002-09-17 2011-01-25 Fluorous Technologies Incorporated Recovery method for catalysts, reagents and co-products
US7364908B2 (en) * 2004-06-17 2008-04-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Separation of fluorous compounds
US20060094866A1 (en) * 2004-11-02 2006-05-04 Gladysz John A Methods, processes and materials for dispensing and recovering supported fluorous reaction components
EP3177402A1 (en) * 2014-08-04 2017-06-14 Gencell Biosystems Limited Triphasic fluid handling
WO2016053186A1 (en) * 2014-09-30 2016-04-07 Agency For Science, Technology And Research Triphasic system for direct conversion of sugars to furandicarboxylic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2149313A1 (de) * 1971-10-02 1973-04-05 Bayer Ag Verfahren zur kontinuierlichen durchfuehrung chemischer reaktionen sowie eine dafuer geeignete vorrichtung
US4454233A (en) 1981-10-21 1984-06-12 Wang Associates Method of tagged immunoassay
US5401847A (en) 1990-03-14 1995-03-28 Regents Of The University Of California DNA complexes with dyes designed for energy transfer as fluorescent markers
US5463082A (en) 1993-07-08 1995-10-31 Exxon Research And Engineering Company Fluorous multiphase systems
US5798032A (en) 1994-06-02 1998-08-25 The Perkin-Elmer Corporation Method and apparatus for automated carbohydrate mapping and sequencing
US5777121A (en) 1996-06-28 1998-07-07 University Of Pittsburgh Fluorous reaction systems
JP4050321B2 (ja) 1996-06-28 2008-02-20 ユニヴァーシティ オブ ピッツバーグ フッ素系反応及び分離システム
US6897331B2 (en) 2001-06-08 2005-05-24 University Of Pittsburgh Fluorous triphase and other multiphase systems

Also Published As

Publication number Publication date
US20030125590A1 (en) 2003-07-03
EP1404687B1 (en) 2006-12-27
US6897331B2 (en) 2005-05-24
WO2002100802A2 (en) 2002-12-19
CA2449445A1 (en) 2002-12-19
CA2449445C (en) 2008-02-05
JP2004529981A (ja) 2004-09-30
DE60217112D1 (de) 2007-02-08
ATE349453T1 (de) 2007-01-15
EP1404687A2 (en) 2004-04-07
WO2002100802A3 (en) 2003-12-11
EP1404687A4 (en) 2004-10-27
AU2002314930A1 (en) 2002-12-23

Similar Documents

Publication Publication Date Title
DE60217112T2 (de) Fluorhaltige dreiphasen- und andere mehrphasensysteme
Kameyama et al. Asymmetric radical reaction in the coordination sphere. 2. Asymmetric addition of alkane-and arenesulfonyl chlorides to olefins catalyzed by a ruthenium (II)-phosphine complex with chiral ligands
DE102013203865A1 (de) Elektrochemische Kupplung zweier Phenole, welche sich in ihrem Oxidationspotential unterscheiden
DE60216815T2 (de) Perfluoradamantylacrylatverbindung und zwischenprodukt dafür
DE3629624A1 (de) Verfahren zur herstellung spiro(indolin)-artiger verbindungen
DE602004002812T2 (de) Alkyl- und Aryl-Trifluormethoxytetrafluorsulfurane
DE69102227T2 (de) Chromatographisches packungsmaterial und dessen herstellung.
DE69521605T2 (de) Optisch aktive diphosphine und herstellungsverfahren durch auftrennung der racematmischung
Underiner et al. Alkylation of allylic derivatives. 14. Relationship of double-bond configuration between reactant and product for cross-coupling reactions of Z-allylic carboxylates with organocopper reagents
EP0158875A2 (de) Chirale Rhodium-diphosphinkomplexe für asymmetrische Hydrierungen
DE60215824T2 (de) Fluorierte nukleophile substitution von alkoholen und reagenzien zur durchführung des verfahrens
DE69922395T2 (de) Verfahren zur herstellung von corrolen und einige solche neue verbindungen, einschliesslich chiraler derivate, sowie deren anwendung
US6734318B2 (en) Fluorous triphase and other multiphase systems
Hayen et al. 1, 3-Stereoinduction in radical reactions: Radical additions to dialkyl 2-alkyl-4-methyleneglutarates
WO2009052809A1 (de) Kupfer-sauerstoff-adduktkomplexe
EP0553778A1 (de) Asymmetrische Hydrierung
DE3207470C2 (enExample)
JP2872800B2 (ja) 光学活性ビフェニル誘導体及び光学分割方法
DE60004651T2 (de) Verfahren zur selektiven fluorierung von organischen verbindungen
DE102005030402B4 (de) Verfahren zur Herstellung von substituierten Halogenpyridinen
Ying et al. N-Fluoro-bis [(trifluoromethyl) sulfonyl] imide: interesting reactions involving nucleophilic attack on sulfonyl groups
EP3470401B1 (de) Verfahren zur photoredoxkatalytischen addition von schwefelhexafluorid an ungesättigte kohlenstoff-kohlenstoff-bindungen
Angle et al. Facile 1, 3-hydride transfer in a cycloheptyl cation
Slocum et al. Metalations utilizing aryllithiums; ortho-functionalization of p-bromoanisole (pBrA)
DE68906250T2 (de) Verfahren zur herstellung von ketonen durch acylierung von organo-manganverbindungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee