CA2449445C - Fluorous triphase and other multiphase systems - Google Patents

Fluorous triphase and other multiphase systems Download PDF

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Publication number
CA2449445C
CA2449445C CA002449445A CA2449445A CA2449445C CA 2449445 C CA2449445 C CA 2449445C CA 002449445 A CA002449445 A CA 002449445A CA 2449445 A CA2449445 A CA 2449445A CA 2449445 C CA2449445 C CA 2449445C
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CA
Canada
Prior art keywords
fluorous
phase
compound
organic
interface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002449445A
Other languages
English (en)
French (fr)
Other versions
CA2449445A1 (en
Inventor
Dennis P. Curran
Stephen G. Weber
Hiroyuki Nakamura
Bruno Linclau
Lifang Sun
Ilhyong Ryu
Hiroshi Matsubara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/877,944 external-priority patent/US6734318B2/en
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Publication of CA2449445A1 publication Critical patent/CA2449445A1/en
Application granted granted Critical
Publication of CA2449445C publication Critical patent/CA2449445C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/04—Substitution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/32—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen
    • C07C1/325—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a metal atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/02—Preparation of halogenated hydrocarbons by addition of halogens to unsaturated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
CA002449445A 2001-06-08 2002-06-05 Fluorous triphase and other multiphase systems Expired - Fee Related CA2449445C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/877,944 2001-06-08
US09/877,944 US6734318B2 (en) 2001-06-08 2001-06-08 Fluorous triphase and other multiphase systems
US10/094,345 2002-03-08
US10/094,345 US6897331B2 (en) 2001-06-08 2002-03-08 Fluorous triphase and other multiphase systems
PCT/US2002/017829 WO2002100802A2 (en) 2001-06-08 2002-06-05 Fluorous triphase and other multiphase systems

Publications (2)

Publication Number Publication Date
CA2449445A1 CA2449445A1 (en) 2002-12-19
CA2449445C true CA2449445C (en) 2008-02-05

Family

ID=26788749

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002449445A Expired - Fee Related CA2449445C (en) 2001-06-08 2002-06-05 Fluorous triphase and other multiphase systems

Country Status (8)

Country Link
US (1) US6897331B2 (enExample)
EP (1) EP1404687B1 (enExample)
JP (1) JP2004529981A (enExample)
AT (1) ATE349453T1 (enExample)
AU (1) AU2002314930A1 (enExample)
CA (1) CA2449445C (enExample)
DE (1) DE60217112T2 (enExample)
WO (1) WO2002100802A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6897331B2 (en) 2001-06-08 2005-05-24 University Of Pittsburgh Fluorous triphase and other multiphase systems
US6734318B2 (en) 2001-06-08 2004-05-11 University Of Pittsburgh Fluorous triphase and other multiphase systems
WO2004007407A2 (en) * 2002-07-11 2004-01-22 Fluorous Technologies Incorporated Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
US7135598B2 (en) * 2002-09-06 2006-11-14 University Of Pittsburgh N-vinylformamide derivatives, polymers formed therefrom and synthesis thereof
US7875752B2 (en) * 2002-09-17 2011-01-25 Fluorous Technologies Incorporated Recovery method for catalysts, reagents and co-products
US7364908B2 (en) * 2004-06-17 2008-04-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Separation of fluorous compounds
US20060094866A1 (en) * 2004-11-02 2006-05-04 Gladysz John A Methods, processes and materials for dispensing and recovering supported fluorous reaction components
KR20170038059A (ko) * 2014-08-04 2017-04-05 젠셀 바이오시스템즈 리미티드 3상 유체의 처리
US20170298039A1 (en) * 2014-09-30 2017-10-19 Agency For Science, Technology And Research Triphasic system for direct conversion of sugars to furandicarboxylic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2149313A1 (de) * 1971-10-02 1973-04-05 Bayer Ag Verfahren zur kontinuierlichen durchfuehrung chemischer reaktionen sowie eine dafuer geeignete vorrichtung
US4454233A (en) * 1981-10-21 1984-06-12 Wang Associates Method of tagged immunoassay
US5401847A (en) * 1990-03-14 1995-03-28 Regents Of The University Of California DNA complexes with dyes designed for energy transfer as fluorescent markers
US5463082A (en) * 1993-07-08 1995-10-31 Exxon Research And Engineering Company Fluorous multiphase systems
US5798032A (en) * 1994-06-02 1998-08-25 The Perkin-Elmer Corporation Method and apparatus for automated carbohydrate mapping and sequencing
US5777121A (en) * 1996-06-28 1998-07-07 University Of Pittsburgh Fluorous reaction systems
AU3581897A (en) * 1996-06-28 1998-01-21 University Of Pittsburgh Fluorous reaction and separation systems
US6897331B2 (en) 2001-06-08 2005-05-24 University Of Pittsburgh Fluorous triphase and other multiphase systems

Also Published As

Publication number Publication date
WO2002100802A2 (en) 2002-12-19
EP1404687A2 (en) 2004-04-07
WO2002100802A3 (en) 2003-12-11
EP1404687B1 (en) 2006-12-27
DE60217112D1 (de) 2007-02-08
EP1404687A4 (en) 2004-10-27
AU2002314930A1 (en) 2002-12-23
US20030125590A1 (en) 2003-07-03
US6897331B2 (en) 2005-05-24
JP2004529981A (ja) 2004-09-30
ATE349453T1 (de) 2007-01-15
CA2449445A1 (en) 2002-12-19
DE60217112T2 (de) 2007-06-06

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