DE60207811D1 - Zusammensetzungen zur entfernung von menschlichem cerumen - Google Patents

Zusammensetzungen zur entfernung von menschlichem cerumen

Info

Publication number
DE60207811D1
DE60207811D1 DE60207811T DE60207811T DE60207811D1 DE 60207811 D1 DE60207811 D1 DE 60207811D1 DE 60207811 T DE60207811 T DE 60207811T DE 60207811 T DE60207811 T DE 60207811T DE 60207811 D1 DE60207811 D1 DE 60207811D1
Authority
DE
Germany
Prior art keywords
cerumes
compositions
removing human
human
human cerumes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60207811T
Other languages
English (en)
Other versions
DE60207811T2 (de
Inventor
D Cagle
R Owen
Jimenez Ridruejo
Michael Wall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of DE60207811D1 publication Critical patent/DE60207811D1/de
Application granted granted Critical
Publication of DE60207811T2 publication Critical patent/DE60207811T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21004—Trypsin (3.4.21.4)
DE60207811T 2001-07-03 2002-06-21 Zusammensetzungen zur entfernung von menschlichem cerumen Expired - Lifetime DE60207811T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30295901P 2001-07-03 2001-07-03
US302959P 2001-07-03
PCT/US2002/019756 WO2003003976A2 (en) 2001-07-03 2002-06-21 Compositions for removing human cerumen

Publications (2)

Publication Number Publication Date
DE60207811D1 true DE60207811D1 (de) 2006-01-12
DE60207811T2 DE60207811T2 (de) 2006-06-29

Family

ID=23169972

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60207811T Expired - Lifetime DE60207811T2 (de) 2001-07-03 2002-06-21 Zusammensetzungen zur entfernung von menschlichem cerumen

Country Status (14)

Country Link
US (1) US20040126436A1 (de)
EP (1) EP1337228B1 (de)
KR (1) KR20040018416A (de)
AR (1) AR034713A1 (de)
AT (1) ATE311898T1 (de)
BR (1) BR0210493A (de)
CA (1) CA2447886A1 (de)
DE (1) DE60207811T2 (de)
DK (1) DK1337228T3 (de)
ES (1) ES2252478T3 (de)
MX (1) MXPA03010881A (de)
NZ (1) NZ530199A (de)
PL (1) PL367523A1 (de)
WO (1) WO2003003976A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2416125A (en) * 2004-07-15 2006-01-18 Michael James Hill Device for supplying fluid to an ear
MX2009005783A (es) * 2006-12-01 2009-10-28 Laclede Inc Uso de enzimas hidroliticas y oxidativas para disolver bio-peliculas en los oidos.
WO2009009156A2 (en) * 2007-07-06 2009-01-15 Laclede, Inc. Use of hydrolytic and oxidative enzymes to dissolve biofilm in airway passages
WO2011085155A2 (en) * 2010-01-07 2011-07-14 Ora, Inc. Formulations and methods for dissolving cerumen
WO2013065051A1 (en) 2011-11-01 2013-05-10 Naveh Pharma (1996) Ltd. Formulation and device for treating ceruminosis
US10154927B2 (en) 2012-06-14 2018-12-18 Earways Medical Ltd. Ear wax removal device and methods thereof
US9133420B2 (en) 2013-01-08 2015-09-15 Ecolab Usa Inc. Methods of using enzyme compositions
WO2014189478A2 (en) 2013-05-23 2014-11-27 Kapar Umut Ear cleaning mixture appliable as foam or in shampoo form
EP3076910B1 (de) * 2013-12-03 2020-09-16 Earways Medical Ltd Vorrichtung zur ohrwachsentfernung
CZ308891B6 (cs) 2014-10-01 2021-08-11 Wald Pharmaceuticals s.r.o Aplikační směs pro zvýšení účinnosti antiseptik a/nebo dezinficiens, aplikační prostředek obsahující aplikační směs, a použití této směsi
US10751295B2 (en) * 2016-11-09 2020-08-25 Specialty Drug and Device, LLC Compositions and methods for the removal of ear wax
WO2018172981A1 (en) 2017-03-24 2018-09-27 Earways Medical Ltd Apparatus and method for treating or/and refreshing an ear canal
US10667678B2 (en) 2018-04-10 2020-06-02 Anna J. Wujciak Ear instrument assembly

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2914442A (en) * 1957-08-27 1959-11-24 Synergistics Inc Novel otologic preparations and the process for their preparation
GB983130A (en) * 1962-08-06 1965-02-10 Mundipharma Ag Improvements in preparations for the removal of wax from the ear
GB1161192A (en) * 1967-01-03 1969-08-13 Burns Pharmaceuticals Inc Wound Debriding and Healing Composition
US3979339A (en) * 1975-03-18 1976-09-07 The Procter & Gamble Company Hard surface cleaning compositions
IT1209419B (it) * 1980-07-01 1989-07-16 Texcontor Ets Composti ad attivita' mucolitica non assimilabili, processo per laloro preparazione e composizioni terapeutiche che li comprendono come principio attivo.
US4556554A (en) * 1981-06-01 1985-12-03 Germaine Monteil Cosmetiques Corp. Immobilized enzymes
DE3606265A1 (de) * 1986-02-27 1987-09-03 Roehm Pharma Gmbh Wundauflage auf polysaccharidbasis als traeger therapeutisch wirksamer, nicht-immobilisierter enzyme und mit hoher saugfaehigkeit
US4921630A (en) * 1986-12-24 1990-05-01 Alcon Laboratories, Inc. Contact lens cleaning compositions containing an enzyme and a carboxy vinyl polymer
US4769171A (en) * 1987-05-11 1988-09-06 Harlmen, Inc. Liquid ear cleansing composition
US4895875A (en) * 1988-06-13 1990-01-23 Church & Dwight Co., Inc. Stabilized peroxide solutions
US5296472A (en) * 1991-12-05 1994-03-22 Vyrex Corporation Methods for delipidation of skin and cerumen removal
EP0546728A3 (en) * 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation
EP0577200B1 (de) * 1992-07-02 1996-07-03 Laboratorios Cusi, S.A. Behälter für pharmazeutische Produkte aus zwei gesonderten Komponenten, mit Mitteln zu deren Mischung und dosierter Ausgabe
US5480658A (en) * 1993-07-23 1996-01-02 Melman; Steven A. Ear and skin cleanser
US5604190A (en) * 1995-06-07 1997-02-18 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5605661A (en) * 1995-08-18 1997-02-25 Alcon Laboratories, Inc. Methods of using liquid enzyme compositions containing mixed polyols
ES2128220B1 (es) * 1995-12-04 1999-12-16 Cusi Lab Envase farmaceutico de dos sustancias separadas, con dispositivo de mezcla, aplicacion dosificada y su proceso de montaje.
US6358897B1 (en) * 1996-06-07 2002-03-19 Alcon Laboratories, Inc. Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
US5954682A (en) * 1996-09-25 1999-09-21 Advanced Medical Instruments Therapeutic applicator apparatus and method
US5897833A (en) * 1996-09-30 1999-04-27 Allergan Systems and methods for disinfecting contact lenses
US6228323B1 (en) * 1996-12-13 2001-05-08 Alcon Laboratories, Inc. Multi-purpose compositions containing an alkyl-trypsin and methods of use in contact lens cleaning and disinfecting
US6417179B1 (en) * 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution
US6309596B1 (en) * 1998-12-15 2001-10-30 Bausch & Lomb Incorporated Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine
US6093417A (en) * 1999-01-11 2000-07-25 Advanced Medical Instruments Composition to treat ear disorders

Also Published As

Publication number Publication date
EP1337228A2 (de) 2003-08-27
US20040126436A1 (en) 2004-07-01
EP1337228A4 (de) 2004-09-01
PL367523A1 (en) 2005-02-21
WO2003003976A2 (en) 2003-01-16
DK1337228T3 (da) 2006-03-20
CA2447886A1 (en) 2003-01-16
AR034713A1 (es) 2004-03-17
WO2003003976A3 (en) 2003-05-30
DE60207811T2 (de) 2006-06-29
NZ530199A (en) 2005-07-29
ES2252478T3 (es) 2006-05-16
EP1337228B1 (de) 2005-12-07
KR20040018416A (ko) 2004-03-03
MXPA03010881A (es) 2004-02-17
BR0210493A (pt) 2004-06-22
ATE311898T1 (de) 2005-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition