DE60204791T2 - Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen - Google Patents

Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen Download PDF

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Publication number
DE60204791T2
DE60204791T2 DE60204791T DE60204791T DE60204791T2 DE 60204791 T2 DE60204791 T2 DE 60204791T2 DE 60204791 T DE60204791 T DE 60204791T DE 60204791 T DE60204791 T DE 60204791T DE 60204791 T2 DE60204791 T2 DE 60204791T2
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DE
Germany
Prior art keywords
formula
compound
solvent
acid
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60204791T
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German (de)
English (en)
Other versions
DE60204791D1 (de
Inventor
Wenxue Wu
Hongbiao Liao
J. David TSAI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
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Application filed by Schering Corp filed Critical Schering Corp
Publication of DE60204791D1 publication Critical patent/DE60204791D1/de
Application granted granted Critical
Publication of DE60204791T2 publication Critical patent/DE60204791T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60204791T 2001-10-15 2002-10-15 Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen Expired - Lifetime DE60204791T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32956101P 2001-10-15 2001-10-15
US329561P 2001-10-15
PCT/US2002/033118 WO2003033488A1 (en) 2001-10-15 2002-10-15 Synthesis of 4-(piperidyl) (2-pyridyl)methanone-(e)-o-methyloxime and its salts

Publications (2)

Publication Number Publication Date
DE60204791D1 DE60204791D1 (de) 2005-07-28
DE60204791T2 true DE60204791T2 (de) 2006-05-18

Family

ID=23285979

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60204791T Expired - Lifetime DE60204791T2 (de) 2001-10-15 2002-10-15 Synthese von 4-(piperidyl) (2-pyridyl)methanon-(e)-o-methyloxim und seinen salzen

Country Status (13)

Country Link
EP (1) EP1436282B1 (https=)
JP (1) JP4425632B2 (https=)
CN (2) CN100360520C (https=)
AR (1) AR036881A1 (https=)
AT (1) ATE298333T1 (https=)
CA (1) CA2463510A1 (https=)
DE (1) DE60204791T2 (https=)
DK (1) DK1436282T3 (https=)
ES (1) ES2240839T3 (https=)
MX (1) MXPA04003477A (https=)
PT (1) PT1436282E (https=)
WO (1) WO2003033488A1 (https=)
ZA (1) ZA200402070B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008008340A (es) * 2005-12-21 2008-09-03 Schering Corp Tratamiento de enfermedad de higado graso no alcoholica usando agentes reductores de colesterol y/o antagonista/agonista inverso de receptor de histamina 3.
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
CN109996793B (zh) * 2017-02-08 2022-02-25 日产化学株式会社 肟基化合物的几何异构体的制造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020507A1 (es) * 2000-10-17 2002-06-25 Schering Corp Compuestos no-imidazoles como antagonistas del receptor histamina h3

Also Published As

Publication number Publication date
DE60204791D1 (de) 2005-07-28
CN101157685A (zh) 2008-04-09
WO2003033488A1 (en) 2003-04-24
JP4425632B2 (ja) 2010-03-03
ES2240839T3 (es) 2005-10-16
PT1436282E (pt) 2005-10-31
EP1436282A1 (en) 2004-07-14
CA2463510A1 (en) 2003-04-24
HK1062683A1 (en) 2004-11-19
CN100360520C (zh) 2008-01-09
AR036881A1 (es) 2004-10-13
ATE298333T1 (de) 2005-07-15
JP2005506357A (ja) 2005-03-03
CN1678605A (zh) 2005-10-05
ZA200402070B (en) 2005-04-29
DK1436282T3 (da) 2005-07-11
MXPA04003477A (es) 2004-07-30
EP1436282B1 (en) 2005-06-22

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